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College basketball picks for the 2025/26 season. Get college basketball expert picks against the spread and totals for the best matchups throughout college basketball every day. We also have you covered for the best action throughout March Madness 2026. Check out our College Basketball Best Bets for our top plays on today’s games.

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12:10 PM ET
Today
CBS
Saint Louis Billikens - NCAAB
Michigan Wolverines - NCAAB
St. Louis
Michigan
Point Spread Pick
Saint Louis Win +12.5(-115)

The Saint Louis Billikens meet the Michigan Wolverines in a Midwest Region second-round game at KeyBank Center in Buffalo, N.Y. on Saturday to kick off the day. Saint Louis cruised past Georgia 102-77 in the opening round, cashing as a 1.5-point favorite as the Over (167.5) cashed. Prior to that cover, SLU was just 1-5 against the spread (ATS) in the previous six, however. The Billikens have cashed the Over in two of the past three games in the postseason, including the Atlantic 10 Conference tournament. However, the Under has a 3-2 edge in five neutral-site games this season, while going 3-1 in four games against teams in the NCAA Tournament, with the lone exception for rout of UGA.

Michigan pounded 16-seed Howard 101-80, but failed to cover as a 30.5-point favorite as the Over (151.5) easily cashed. However, the Under was 2-1 in the Big Ten tournament for Dusty May’s bunch, while the Under is 5-3 in the past eight neutral-site games for the Wolverines. Michigan has also failed to cover the past six games, while going 1-8 ATS in the previous nine outings. If you’re looking for a same-game parlay (SGP) opportunity, going Under on the total, coupled with Saint Louis is the way to go. If you’re looking for just a singular play, the Billikens catching double digits is the play. Michigan is 0-6 ATS in the past six tries as a favorite of 9.5 or more points.

Saint Louis +12.5 (-115) at time of publishing. Playable to +11.5.

2:00 PM ET
Today
CBS
Louisville Cardinals - NCAAB
Michigan State Spartans
Louisville
Michigan State
Money Line PickBest Bet
Louisville Win(+140)

If you bet the Cardinals on Thursday, you likely suffered one of the worst beats in recordable memory. Let’s run it back. South Florida was the trendy underdog in the Thursday slate as a popular choice for a 6 vs. 11 upset and were bet down to as low as -3.5, before the market stabilized at -4.5. Remember that. The Cardinals led by as much as 19 deep into the second half before somehow the Bulls would surge and get to within four points. And here we go.

With ticks left on the clock, Louisville was sent to the line for two free throws. One basket fosters a UL cover and erases the backdoor. The Cards would miss both free throws and win by four. What does that do for anyone eyeing Louisville in their follow up? Avoid at all costs. Michigan State meanwhile academically handled North Dakota State in a 25-point rout and generated an easy win for those that layed the lumber with Sparty. Put this all together and you have the perfect opportunity to back the Cards. Had Louisville routed South Florida, there would have been a zig-zag and the market would have more interest in the Cardinals, especially with points. The line also would have been shorter, inside a basket. As a result of the contrasting outcomes between MSU and The Ville, we get the Cardinals at an enhanced price in a game they can still clearly win. Take Louisville outright.

Louisville vs Michigan State prediction: Louisville ML (+140) available at time of publishing. Playable to the number.

Vote on who will win!

2:00 PM ET
Today
CBS
Point Spread Pick
TCU +11.5(-115)

#9 seed TCU Horned Frogs will take on the #1 seed Duke Blue Devils on Saturday, with both teams looking to deliver a stronger performance than they showed in the first round. TCU narrowly escaped Ohio State, needing a game-winning layup from Xavier Edmonds with just four seconds remaining. Duke also had a sluggish start, only pulling away from #16 seed Siena in the final minutes. Both teams enter this matchup with a defensive identity. According to KenPom, TCU ranks 22nd in adjusted defensive efficiency (97.5 points allowed per 100 possessions) and Duke leads the nation with 89.8. 

For Duke, the key will be establishing control inside. TCU struggled in the paint against Ohio State, getting outscored 34-24, and that’s an area where Duke typically thrives. Even in their win over Siena, the Blue Devils held a 36-30 edge in the paint. However, they haven’t been as dominant inside as usual in recent games, especially with Patrick Ngongba II and Caleb Foster out of the lineup. TCU has the offensive firepower to keep pace with the Blue Devils, with four players averaging double figures. That balance should help them match up against Duke’s top options like the Boozer brothers and Isaiah Evans. The Horned Frogs have also proven they can compete with high-level teams, picking up wins over Cincinnati, Texas Tech, and Iowa State during the regular season while keeping other top-25 matchups close. While TCU may not have enough to pull off the upset, their physicality and defensive toughness should keep this game close. If Duke controls the glass and consistently scores in the paint, they’ll create separation – but I expect TCU to battle inside and keep this one within single digits. 

TCU vs Duke prediction: TCU +11.5 (-115) available at time of publishing. Playable at that number.

6:10 PM ET
Today
TNT
Texas A&M Aggies
Houston Cougars - NCAAB
Texas A&M
Houston
Point Spread Pick
Houston -9.5(-110)

After a highly entertaining opening day of March Madness action that featured plenty of compelling college hoops, Friday’s slate was largely a letdown. However, we should get plenty of compelling matchups in the Round of 32 this weekend, including a battle between the Texas A&M Aggies and Houston Cougars. Based off what we just saw on Thursday, I can understand the case for backing Texas A&M at this number. After all, the Houston offense can be prone to extended scoring droughts and the Aggies are fresh off a dominant victory over a Saint Mary’s team that plays a somewhat similar defense-focused style to what the Cougars focus on. However, that performance was more about Saint Mary’s and the Gaels’ complete lack of athleticism than what the Aggies were bringing to the table, specifically on the defensive side of the ball.

Compared to most of its opponents this season, Houston is a much tougher matchup for this Texas A&M. The Aggies thrive on outworking the opponent and creating chaos, but they won’t be able to accomplish that against a Cougars team that is elite at taking care of the basketball (5th in turnover rate) and generating offense late in the shot clock. More importantly, Kelvin Sampson’s team consistently dominates the glass and should hold a massive edge on the offensive boards against an Aggies defense that is 280th in defensive rebounding percentage (BartTorvik). Ultimately, Texas A&M is well outside the top 200 in 2-point percentage defense, and we can expect Kingston Flemings and the Houston offense to have enough to win this game by double digits.

Texas A&M vs Houston prediction: Houston -9.5 available at time of publishing. Playable to Houston -10.5

7:10 PM ET
Today
TBS
Texas Longhorns
Gonzaga Bulldogs
Texas
Gonzaga
Point Spread Pick
Gonzaga Win -6.5(-110)

The Round of 32 matchup between the Texas Longhorns and Gonzaga Bulldogs sets up as one of the more intriguing games of the weekend, featuring two teams coming off impressive opening round wins. Texas advanced with a 79-71 victory over the BYU Cougars, showcasing a balanced offensive attack and strong guard play. The Longhorns enter averaging 75.2 points per game while shooting 45.8% from the field, and they’ve been particularly effective when controlling tempo and limiting turnovers. Defensively, Texas allows 70.4 points per game, and their ability to contest shots on the perimeter has been key, holding opponents under 34% from three point range. Guard play remains the backbone of this team, with multiple contributors capable of initiating offense and creating late clock scoring opportunities.

Gonzaga enters this matchup in strong form after a 73-64 win over Kennesaw State Owls, continuing their trend as one of the most efficient offensive teams in the country. The Bulldogs average 83.6 points per game while shooting an impressive 50.6% from the field, ranking among the top teams nationally in offensive efficiency. They also dominate the glass, pulling down 40.7 rebounds per game, which creates consistent second chance opportunities. Gonzaga’s offensive structure is built on ball movement and interior scoring, complemented by efficient perimeter shooting at 37.8% from three. Defensively, they allow 69.1 points per game, and their size inside often forces opponents into difficult half court possessions. While Texas has the defensive discipline and guard play to keep this competitive early, Gonzaga’s offensive consistency, rebounding edge, and ability to generate high percentage looks should allow them to gradually create separation. If the Bulldogs control tempo and win the battle on the boards, they are well positioned to advance to the Sweet 16.

Texas vs Gonzaga prediction: Gonzaga -6.5 (-110) available at time of publishing. Playable to -7.5.

7:50 PM ET
Today
CBS
VCU Rams - NCAAB
Illinois Fighting Illini
VCU
Illinois
Game Totals Pick
Over 151.5(-115)

The VCU Rams and the Illinois Fighting will meet on Saturday in the round of 32 of the NCAA Tournament. VCU is coming off an improbable comeback against North Carolina last game to move onto the next round. They are one of two 11 seeds to upset a six seed in the first round and have a chance to win again here. Illinois is coming off a blowout win against Penn in the first round and will look to make their second Sweet 16 in three years. The Rams are an 11.5-point underdog, but I am backing the over in this game.

I like the over in this game because VCU will look to push the pace as much as possible and Illinois has one of the best offenses in the country. According to KenPom, VCU is ranked #59 nationally in average offensive possession length and #117 in adjusted tempo. To compete with Illinois, I expect VCU to try to speed up the game and make the Illini uncomfortable. Illinois plays slow but have the second ranked offensive efficiency at KenPom, which should help drive the total over. Illinois offense is ranked #36 in effective field goal percentage, #6 in offensive rebounding percentage and #20 in two-point percentage. Take the over here.

*Over 151.5 available at time of publishing. Playable at 152*  

Vote on who will win!

8:45 PM ET
Today
TNT
Vanderbilt Commodores - NCAAB
Nebraska Cornhuskers - NCAAB
Vanderbilt
Nebraska
Money Line Pick
Nebraska Win(-104)

The #3 Nebraska Cornhuskers face the #6 Vanderbilt Commodores on Saturday night. Vanderbilt has been red hot down the stretch, although it was not easy bouncing McNeese St on Thursday. The Huskers got off the trivia list as the last remaining major conference team to never win a tournament game; they smoked Troy by nearly 30 to do it. The contrast in styles will be interesting in this one, as Vanderbilt has elite guards and a top-notch offense, while Nebraska is an elite defense that also makes a lot of 3s. Vandy opened as the favorite, despite being the lower seed, but I like Nebraska to win this game outright. I’ll take Nebraska on the Money Line.

The difference in this game ought to be the Cornhusker defense. They rank in the top 10 in the nation in 3-pt percentage allowed, and Vandy lives on that arc. If Nebraska suppresses those outside shooters, the ‘Dores will have trouble. Nebraska is also the better team on the boards, and they can more than hold their own offensively. The Vanderbilt defense is the weakest link in this game, and while this is likely to be a high-scoring shootout, Nebraska seems to just enough of an edge for me to back them.

Vanderbilt vs Nebraska Prediction: Nebraska ML (-105) available at the time of publishing. Playable at that number.

Vote on who will win!

9:45 PM ET
Today
truTV/TBS
High Point Panthers
Arkansas Razorbacks
High Point
Arkansas
Game Totals Pick
Over 168.5(-115)

The scoreboard operator better limber up his/her fingers, because they’re going to be busy. Arkansas averaged 90.1 points per game (PPG) this season, ranking No. 3 in the nation. Right on its heels, High Point averaged 89.8 PPG, ranking No. 4 in the country. This game figures to be a track meet. High Point had the late-game heroics to surprise Wisconsin 83-82 as a 10.5-point underdog in Round 1, pulling off a 12-5 upset as the Over (161.5) cashed. The Over also cashed against Winthrop in the Big South Tournament Championship Game, while going 4-2 in the past six outings, 7-3 in the past 10 games, and 12-5 across the previous 17 contests.

For Arkansas, it cruised by Hawaii 97-78 in the first round, cashing as a 13.5-point favorite, avoiding the 13-4 upset with ease. The Over (158.5) cashed, too, which was a frequent happening with Coach John Calipari’s squad. The Over is just 2-2 in four postseason games, including the SEC Tournament, but the total has gone high in eight of the past 10 games since Feb. 18. In addition, Arkansas has scored at least 82 points in six consecutive outings, while hitting that mark in 12 of the past 13 contests. Arkansas has also allowed at least 75 points in 11 in a row. Look for a track meet in Portland to wrap up the Saturday second-round action.

Over 168.5 (-110) at time of publishing. Playable to 169.5.

Vote on who will win!

The Home Of Free College Basketball Expert Picks For The 2025/26 Season

College basketball picks for the 2025/26 season. Our experts crunch the numbers, betting trends, injury reports, and much more to produce the best free college basketball picks and every day throughout the season and into March Madness itself. 

Unlike many places, here at Pickswise, we have you covered all season long, whether it’s non-conference play, conference play, championship week, or March Madness, our NCAA basketball picks have you covered. Our College Basketball picks include a pick against the spread as well as on the points totals market, and both come with expert analysis and the key stats and trends. Check out our free college basketball picks today, and get all the latest College Basketball Odds

Free College Basketball Picks Explained

With 353 Division I college basketball teams there are plenty of opportunities to find good value college basketball picks. With so many games played each day it is impossible for sportsbooks to get the lines correct for every single match. As sports bettors, this gives us a great opportunity to research the games, and find those edges to better serve our chances of long-term wagering success. That’s precisely what we do here at Pickswise. Our dedicated college basketball team covers every morsel of NCAAB action, leaving no stone unturned in the search for the best value picks for the top CBB action, and NCAA Basketball Futures, all of which are accompanied with full analysis, for free, only here at Pickswise. 

Free College Basketball Picks Against The Spread (ATS)

One of the more popular college basketball wagers is betting against the spread (ATS). Against the spread betting isn’t just picking a winner of the basketball game, it’s about picking the team who will win by a set margin, known as covering the spread.

Let’s say you bet your money that Team A covers the spread (wins by a certain amount of points), Duke -6.5 for example. Or that Team B will cover the spread (keep the game closer than oddsmakers expect), Kentucky +6.5. If Duke beat Kentucky 64-60, then Kentucky would cover the spread, and underdog backers will cash their tickets on Kentucky +6.5 points.

The disparity is a big thing in many college basketball matchups and as such Moneyline betting will often see small odds about a favorite. Betting against the spread is very common, for this reason. It allows bettors to wager on the big favorites, who are expected to win,  at better odds, but also the opportunity to bet the underdog. These are the main reasons why college basketball against the spread betting is so popular, but it is also  one of our most popular college basketball picks on Pickswise. This is because knowing when an underdog might keep a game close or when potentially evenly matched teams might have blowout is very hard to predict without all the research, expertise, analysis and data our team has at its disposal. 

Free College Basketball Totals Picks (Over/Under)

The other main NCAAB wager is the totals which are simply betting over or under a set number of points in a game. This market is seen to be one of the easier markets to beat the book if you can get to grips with some of the most important statistics which contribute to how many points will be scored in a ball game.

Some of the most important factors to consider when handicapping totals in basketball are the number of possessions per team in a game and the pace of play. Our experts at Pickswise consider these key angles as well as matchups, injuries, and betting trends to determine which side of the line has the best chance of hitting, and we have a strong record of getting this right.

CBB Picks

All of our CBB picks are posted right here on the college basketball picks page, all season long. Our experts post their top CBB picks, along with a detailed analysis including the key stats and matchups ahead of that game. Our CBB picks include a pick on the money line, spread, and totals for every match we cover, check them out today. we also have reliable College Basketball Predictions daily throughout the season.

College Basketball Parlay Picks

With so many games available to bet on there’s always great potential for College Basketball Parlays. You could make it a multi-game pick combining different money line or against the spread bets or you might want to get creative with other bet types within a single game parlay. Remember when you parlay you need all included bets to win to cash your wager, but with all those odds multiplied it can be very lucrative.

The statistical method for NCAA Basketball Picks

Just like pro sport teams, the college basketball teams that have success often take a very statistical approach to their decision making, so why wouldn’t you do the same for your bets on them?

At Pickswise we don’t believe in chance bets, our expert team comb through all the data, do all the analysis and provide all their research so you can have confidence in our College basketball picks.

Andrew Wilsher, Pickswise Managing Editor

More Than Just College Basketball Picks

At Pickswise we don’t just cover College Basketball Picks, collegiate sports fans will be pleased to know we also have free weekly expert College Football Picks too.

We also have expert handicappers for each of the professional sports in North America including our NFL Picks, MLB Picks, NBA Picks, and NHL Picks. Check out all of our sports betting picks today.