Arizona State Sun Devils vs Iowa State Cyclones Prediction, Odds and Picks for Today, 03/11/26

The first game on the slate for the Big 12 on Wednesday is the Arizona State Sun Devils vs the Iowa State Cyclones. ASU played on Tuesday and dispatched Baylor with some hot shooting out of the gates. Iowa State will play their first game of the tournament. Their last game was, coincidentally, against this same Arizona State bunch, whom the Cyclones beat 86-65. I anticipate a fairly similar result, so even though the number is large, I am backing Iowa State here at -11.5.

There really wasn’t anything unexpected about the outcome when these teams met a few days ago. Most of the stats were in line with the teams’ statistical profiles. The obvious difference in the game was the turnovers, as the Sun Devils not only turned it over a ton, but also gave up transition points. But Iowa State is a top 5 defensive team in terms of creating turnovers, so that is more or less expected. There is a lot going on with the Sun Devils these days, including reports that the school will move on from coach Hurley when this tournament finishes. I think Iowa State delivers in this spot.

Arizona State vs Iowa State Prediction: Iowa State -11.5 (-110) available at the time of publishing. Playable at that number.