Butler Bulldogs vs Connecticut Huskies Prediction, Odds and Picks for Today, 12/16/25

Butler heads into this Big East matchup as a sizable underdog, but the Bulldogs’ early season profile suggests they’re capable of staying competitive against elite opponents. Butler has leaned into a disciplined, half court approach, averaging around 72 points per game while emphasizing ball security and shot selection. Their offense runs largely through a balanced backcourt, with multiple guards averaging double figures, and they’ve shown a willingness to grind possessions rather than trade quick shots. Defensively, Butler has been solid in the half court, holding opponents under 44% shooting, and they’ve done a respectable job limiting transition chances—an important factor when facing a team like UConn that thrives when games open up. While Butler doesn’t overwhelm teams with athleticism, their structure and patience often allow them to hang around longer than expected.

UConn, meanwhile, continues to look every bit like a national title contender. The Huskies average over 82 points per game, pairing elite offensive efficiency with physical defense that wears teams down over 40 minutes. Their frontcourt depth and rebounding edge are major strengths, as UConn routinely controls the glass and turns missed shots into second chance points. Defensively, they allow just around 66 points per game, using size and switching ability to contest shots without fouling. Still, UConn’s dominance doesn’t always translate to runaway margins, particularly against conference opponents that know how to slow the game and execute in the half court. The Huskies are just 1-6 ATS at home this year and I expect another close one in Connecticut tonight.

Butler vs UConn Prediction: Butler +15.5 (-110) available at time of publishing. Playable to +13