Butler Bulldogs vs Creighton Bluejays Prediction, Odds and Picks for Today, 12/30/25

It’s a Big East showdown as the Butler Bulldogs make their way to Omaha Nebraska to take on the Creighton Blue Jays. The Bulldogs enter this matchup with a 10-3 record and are 1-1 in Big East play this season. The Blue Jays sit at 8-5 overall and are a perfect 2-0 in conference action. Creighton appears to have found its groove, winning three straight games while averaging 91.3 points per game and holding opponents to just 63 points during that stretch. Butler is coming off back-to-back wins as well, but they narrowly escaped against Northwestern, where they shot 38% from the floor. 

Offensively, Butler holds a slight edge, averaging 86.4 points per game compared to Creighton’s 78.5. Leading the Bulldogs is Michael Ajayi who is averaging 16.6 points, 12.2 rebounds, and 3.0 assists per game and the Blue Jays are going to need to find a way to slow him down if they want to win this matchup. The Blue Jays just have one player averaging double digits this season, Josh Dix, who is averaging 12.2 points, 3.5 rebounds, and 2.9 assists per game. Home-court advantage could be a major factor here. Butler is 0-2 on the road this season, while Creighton has been dominant at home with a 6-1 record. This should be a competitive matchup, and you could make a case for either side, but Creighton’s recent form and strong play at home gives them the edge. Taking everything into consideration, look for the Blue Jays to take care of business on their home court against their Big East rivals.

Butler vs Creighton prediction: Creighton -5.5 (-110) available at time of publishing. Playable at that number.