DePaul Blue Demons vs Connecticut Huskies Prediction, Odds and Picks for Today, 01/10/26

We kick off the early slate of college basketball with the DePaul Blue Demons vs the UConn Huskies. UConn is clearly the class of the Big East, although they did need overtime to survive at Providence earlier this week. DePaul is riding a modest 2-game winning streak, beating Georgetown and Xavier. DePaul is better than they have been in the past, but a trip to Storrs is just not likely to be successful. I’ll take the Huskies to cover -19.5.

These two teams faced off in December with UConn winning on the road, 72-54. I do not expect Depaul to do much better in this game. While DePaul is certainly better than they have been in recent years, this is still a team that struggles mightily on the offensive end of the floor. They play slowly, and they sit outside the top 200 in offensive efficiency. They consistently struggle to get above 60 points, and that would seem like the absolutely ceiling against a team like UConn with a top-5 defensive team. I just don’t see the path for the Blue Demons, particularly on offense, and I expect UConn to roll. It’s a big number, but it is the wiser play.

DePaul vs UConn Prediction: UConn -19.5 (-110) available at the time of publishing. Playable at that number.

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