Florida Gators vs Arizona Wildcats Prediction, Odds and Picks for Today, 11/03/25

It is opening night for college basketball, and the headliner is a battle of 2 of the top teams in the country in the gambling capital of the world, as the Florida Gators take on the Arizona Wildcats in Las Vegas. The Gators are, of course, the defending national champs, and their roster is still plenty loaded. The Wildcats are consistently one of the best teams in the nation, and this year should be no different for head coach Tommy Lloyd’s bunch. Both the Big 12 and the SEC are every bit as loaded from top to bottom as they were a season ago, and each of these teams is among the upper cut of those conferences. Which way shall we play it? I am going to take the points with the Wildcats, as I am looking for a close, up-tempo battle between 2 of the nation’s best.

Let’s start with the Gators. The big loss is Walter Clayton, who was not only the most talented player but also the spiritual and emotional leader of last year’s championship team. The roster does, however, return big man Alex Condon inside and they lured Boogie Fland away from Arkansas to lead this backcourt. They were active in the portal and probably have as much depth as anyone in the country. As for Arizona, the key players are veteran Jaden Bradley at PG and Koa Peat, a 6’8” freshman who should be a future lottery pick. Lloyd also brought in 5-star freshman guard Brayden Burries, a top-10 national recruit.

Florida is a veteran team that might need to learn one another in the season’s opening weeks. Arizona is a young team with sky-high talent and potential, if it is not overwhelmed by the moment. We never really know how teams will come out of the gates, so I don’t want to hammer anything in this spot, but I do like the chances of the Wildcats giving a formidable test to the defending champs right out of the gate. I’ll take the points with the Wildcats.

Florida vs Arizona prediction: Arizona +3.5 (-110) available at time of publishing. Playable at that number.

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