Georgetown Hoyas vs Villanova Wildcats Prediction, Odds and Picks for Today, 01/21/26

Georgetown and Villanova as a rivalry is second to none. However, the market is putting too much weight on the mechanics of animosity more than the teams on the floor. The Wildcats are significantly better than the Hoyas and that is why they are favored as they are here.

The Hoyas are in free-fall. Georgetown has lost five straight. The market will point out that three of these losses were close defeats against UConn, at Creighton, and at DePaul but that’s all fodder. The Hoyas struggle to close games and they invent new ways to lose. This is a team that cannot sustain defensive or offensive pressure for two full halves. Nova meanwhile is 7-2 SU in their last nine outings. Over this span, the Cats have knocked off Wisconsin, Butler, and Seton Hall all on the road. These are three teams that are bubble teams for March and Villanova handled them in their own barns. Add in that the Wildcats are 8-2 in their own stead and this is a contest that very quickly could get away from Georgetown. The Hoyas may have won the last two between these rivals but that all changes tonight. Lay the points and don’t look back.

Georgetown vs Villanova prediction: Villanova -9.5 (-110) available at time of publishing. Playable to -10.