Iona Gaels vs St. John's Red Storm Prediction, Odds and Picks for Today, 12/13/25

This is simply too many points to ignore with an Iona team that has shown it can score with anyone. The market price here has far less to do with matchup specifics and far more to do with branding. St. John’s is a regional power, a ranked program with March upside, and when you back teams like that, you pay a premium. That premium is fully baked into this number. Iona, meanwhile, gets taxed in the opposite direction. Before the Gaels even take the floor, they’re handed an inflated spread simply because they don’t carry the same logo equity. But this isn’t a plucky, low-scoring underdog that needs everything to go right. Iona owns a top-50 offense nationally, averaging north of 80 points per game, and that matters immensely when you’re catching this kind of margin.

Even if St. John’s controls the game — which is entirely possible — Iona’s offense doesn’t shut down when trailing. They continue to push pace, take shots, and score late, which is exactly how large numbers get threatened. That’s why the Gaels haven’t been blown out by anything close to this margin all season. To cover, the Johnnies would need to flirt with triple digits while also clamping down for a full 40 minutes, and that’s asking a lot. This isn’t about predicting an upset or even a competitive game throughout. It’s about math. It’s about possessions. And it’s about an offense capable of keeping the backdoor wide open. Gaels plus the points.

Iona vs St. John’s prediction: Iona +27.5 (-110) available at time of publishing. Playable to +27.