Missouri Tigers vs Kansas Jayhawks Prediction, Odds and Picks for Today, 12/07/25

No. 21 Kansas welcomes Missouri as the Jayhawks look to rebound from their tough loss against No. 5 UConn earlier in the week. Kansas started fast in that matchup, but the offense stalled in the second half, managing just 23 points. MIsouri, meanwhile, is coming off a 76-71 loss to Notre Dame – a team Kansas beat by 10. This is a step up in competition for the Tigers, and the Jayhawks have the edge in this matchup and here’s why. 

According to KenPom, the Jayhawks rank 10th in Adjusted Defensive Efficiency compared to Missouri who ranks 70th in that category. Neither team likes to play at a fast pace, and the Jayhawks will look to cool off a Missouri team that’s averaging 90.4 points per game this season. Kansas managed to hold UConn to just 61 points, Tennessee to 76, and Duke to 78, and all three of them have a very dangerous and deep offense. Flory Bidunga will be a nightmare for the Tigers –  the sophomore is averaging 15.2 points and 8.8 rebounds per game. Shawn Phillips Jr. is a 7 ‘0 senior for Missouri who’s averaging 9.1 points and 6.4 rebounds per game, and he’ll try to box out Bidunga in this matchup, but he won’t have much success. The Jayhawks’ defense should be able to cool down the Tigers offensively, and Melvin Council Jr., Bidunga, and Tre White should help their team pick up a much-needed win at home on Sunday afternoon. 

Missouri vs Kansas prediction: Kansas -6.5 (-105) available at time of publishing. Playable at that number.

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