Northwestern Wildcats vs Indiana Hoosiers Prediction, Odds and Picks for Today, 03/11/26

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#15 seed Northwestern took care of business yesterday against #18 seed Penn State, shooting 50.9% from the floor and outrebounding the Nittany Lions 28-22. The Wildcats weren’t as sharp defensively as they would’ve liked, allowing Penn State to shoot 51% from the field. However, they did pressure the Nittany Lions into 17 turnovers, converting those into 24 points. Taking a look at today’s matchup against #10 seed Indiana, these two teams last met on February 24th where Northwestern won 72-68. The Wildcats held the Hoosiers to 46% shooting, and they were able to slow down Lamar Wilkerson who went 5-17 from the field. Northwestern’s defense did a great job shutting down the driving lane for Indiana, forcing the Hoosiers to rely more on perimeter shooting. Expect to see that same defensive pressure from the Wildcats again as they look to advance past Indiana. 

On paper, both teams are fairly similar. Northwestern is averaging 73.3 points per game compared to Indiana’s 78.7. Defensively, the Wildcats are giving up 72 points per game compared to the Hoosiers 72.1. Indiana does have a slight rebounding advantage, averaging 36 per game compared to Northwestern’s 34, and Tre Singleton could be an issue inside for the Hoosiers. Nick Martinelli leads this Wildcats team with 22.8 points and 6.3 rebounds per game. For Indiana, Lamar Wilkerson leads with 21 points per game. This should be a great matchup between two evenly matched teams, and we’ve seen how efficient Northwestern’s offense can be, but they’ll need to shut down the driving lanes and control the boards if they want to stay in this game. Indiana comes into this matchup rested, but they’ve struggled down the stretch, losing five of their last six games. Northwestern, on the other hand, has played better basketball late in the season, winning four of their last six. The Wildcats have been a tough opponent all season long, and I expect Martinelli to lead the way again and help Northwestern keep this game close against Indiana.

Northwestern vs Indiana prediction: Northwestern +4.5 (-115) available at time of publishing. Playable at that number.

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