Oregon Ducks vs Purdue Boilermakers Prediction, Odds and Picks for Today, 02/07/26

The Purdue Boilermakers host the Oregon Ducks in a B1G matchup on Saturday afternoon. The Boilermakers are one of the nation’s elite teams, but they have hit a rough patch lately. They have dropped 3 of their last 4 games, which also coincides with a heavy stretch of road games (4 of their last 5). They will look to get back on track against the beat-up and struggling Ducks, who have lost 8 straight and have fallen to 1-10 in the conference standings. For Oregon, the problem has been injuries. This is a giant spread, and it is hard to feel really confident about playing a spread this large in a conference game, but I think it is the most likely outcome on Saturday. Give me Purdue -20.5.

For Oregon, the injuries have wrecked the season. Guard Jackson Shelstad remains out, among other players, and while leading scorer Nate Bittle is officially listed as questionable, it would be a surprise to see him return in this spot. Without those guys, this Oregon team is in shambles, and they really don’t do anything well. Purdue, on the other hand, does seemingly everything well. They rebound the heck out of the ball, and they defend everything. They do not play fast, but their offense is ruthlessly efficient. They just blasted Maryland by 30 on the road, and assuming Bittle doesn’t return for this matchup, the Boilermakers may do the same thing to the Ducks here. This is a bad spot for Oregon, and they will probably just end up taking their medicine.

Oregon vs Purdue Prediction: Purdue -20.5 (-110) available at the time of publishing. Playable at that number.