Purdue Boilermakers vs Alabama Crimson Tide Prediction, Odds and Picks for Today, 11/13/25

Despite defeating Oakland in its last game, Purdue dropped from No.1 to No.2 in the AP Polls ahead of its trip to Tuscaloosa to take on No.8 Alabama. This will be the toughest test for Purdue this season, and even though Purdue is without the great Zach Edey, the Boilermakers have Oscar Cluff – who’s 6’11, averaging 11.5 points and 9.5 rebounds per game. The Boilermakers weren’t sharp against Oakland, allowing 44.1% shooting while hitting just 47.1% themselves. Alabama dominated North Dakota 91-62 to open the season, then outlasted No.5 St. John’s and walked away with a 103-96 victory after shooting 48.1% from the field.

According to KenPom, Purdue ranks 44th in adjusted defensive efficiency (98.1), while Alabama sits slightly higher at 38th (97.5). Purdue will look to slow down the tempo, but Alabama plays at such a fast pace, it’s going to be tough. According to KenPom, Alabama ranks 2nd nationally in adjusted tempo, and freshman Labaron Philon leads this Crimson Tide team with 23.5 points and 5.5 assists per game. He’s just 1 of 5 players averaging double figures. For Purdue, senior Fletcher Loyer leads with 22.5 points and 1.0 assists per game, but the Boilermakers haven’t looked sharp in their first 2 games. The Tide have played like they should be No.1 in the country, and I expect them to rally behind their home crowd and take down No.2 Purdue in tonight’s matchup.

Purdue vs Alabama prediction: Alabama Crimson Tide -4 (-110) available at time of publishing. Playable at that number.

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