South Carolina Gamecocks vs Clemson Tigers Prediction, Odds and Picks for Today, 12/16/25

South Carolina enters this rivalry matchup at 7-3, averaging 80.1 points per game while allowing 68.2 PPG, and they’ve shown flashes of offensive efficiency when their shooting is on. The Gamecocks hit 45.7% from the field and protect the ball well, committing fewer than 10 turnovers per game, which helps them stay competitive in most contests. Their scoring is fairly balanced, and when they find rhythm early, they can push pace and hang with quality opponents. However, consistency remains an issue — South Carolina’s performance tends to swing based on shooting variance, and they’ve struggled to maintain efficiency for a full 40 minutes against more structured, physical teams.

Clemson, on the other hand, has been the steadier and more reliable side at 8-3, especially at home where they remain unbeaten. The Tigers average 81.8 PPG and give up just 66.4 PPG, pairing efficient offense with a disciplined defensive approach. One of Clemson’s biggest edges is on the glass, pulling down over 41 rebounds per game, which often translates into extra possessions and easier scoring opportunities. Their balanced scoring and ability to control tempo allow them to gradually wear teams down, particularly in home environments where their defensive intensity ramps up. Against a South Carolina team prone to offensive lulls, Clemson’s rebounding advantage, defensive consistency, and home court edge create a clear path to separation.

South Carolina vs Clemson Prediction: Clemson -12.5 (-110) available at time of publishing. Playable to that number

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