Western Michigan Broncos vs Ohio State Buckeyes Prediction, Odds and Picks for Thursday, 11/20/25

Western Michigan will travel to Columbus Ohio on Thursday night to take on undefeated Ohio State. The Broncos are coming off a loss against South Dakota in which they shot an impressive 53.3% from the field, but their turnovers were costly. Western Michigan turned the ball over 13 times, which South Dakota capitalized on, scoring 21 points. So far this season, Western Michigan averages 16.4 turnovers per game, and that’s something Ohio State will take note of and will look to apply pressure, hoping they can force the Broncos to turn it over. 

Ohio State is coming off a narrow 64-63 win over Notre Dame and will look to improve its shooting after finishing just 38% from the field in that game. The Buckeyes have 4 players scoring in double figures this year, led by senior Bruce Thornton, who averages 25.3 points, 3.5 assists, and 4.3 rebounds per game. Western Michigan can score as well, averaging 80 points per game, and a big part of its offense is Jayden Brewer, who averages 17.2 points and 9 rebounds per game. However, the Buckeyes are averaging 87.8 points per game, and they should be able to capitalize against this Broncos defense, which allows 80.2 points per game. Ohio State has the better offense and defense in this matchup, and I expect them to overpower the Broncos and move to 5-0 on the season. 

Western Michigan vs Ohio State prediction: Ohio State Buckeyes -27.5 (-110) available at time of publishing. Playable at that number.

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