College Football Picks

Get free college football picks for the best action throughout 2025-26 season, including college football picks against the spread, straight-up, money line picks, and total picks (over/under). Our data-devouring experts find you the best betting trends and NCAAF picks this week.

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7:00 PM ET
Today
ESPNU
Central Michigan Chippewas
Kent State Golden Flashes
Central Michigan
Kent State
Point Spread Pick
Central Michigan -9.5(-110)

Part of this week’s MACtion takes us to Kent State where the Golden Flashes will host the Central Michigan Chippewas. The visiting Chippewas are very much in the hunt for the MAC title game, sitting at 4-2 in the conference standings in a logjam of 5 teams. Oddly enough, Kent State is only a game back in the standings after upending Akron last week. Kent State, as a reminder, did not win a game last year, fired its coach in April and was fully expected to finish last in the conference again this year. Yet the Golden Flashes have found a lot of success. I’ll admit that they have beaten me more than once in these MACtion games, but I just don’t see how they are successful — and this one seems like a bad matchup for Kent State. Give me Central Michigan -9.5.

Central Michigan is a run-first offensive scheme. The Chippewas are very effective on the ground, and Kent State is outside the top 100 in terms of rushing defense. They should to be able to run the ball at will in this spot. Also, it is going to be cold on Wednesday — probably in the upper 30s most of the game. In that kind of weather, you want to be the team that can run effectively. As far as Kent State goes, just a reminder that it ranks 131 (out of 134) in the nation in terms of total offense — I don’t see how this team ever scores. Understanding that midweek MACtion games are just plain weird sometimes. The Chipps should be able to control this game on the ground against a bad rush defense, setting them up nicely to win by 2 scores.

Central Michigan vs Kent State prediction: CMU -9.5 (-110) available at time of publishing. Playable at that number.

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7:00 PM ET
Today
ESPN2
Miami (OH) Redhawks
Buffalo Bulls
Miami Ohio
Buffalo
Game Totals Pick
Under 40.5(-110)

Midweek MACtion rolls right along on Wednesday of Week 13. With just 1 team at 5-1 in conference and 5 teams at 4-2, the MAC race feels wide open. Wednesday’s matchup between the Miami RedHawks and the Buffalo Bulls will go a long way toward deciding who plays for a MAC title given both teams are among the gaggle of 4-2 teams. However, that somehow may not even be the biggest headline coming into this game. Miami QB Dequan Finn decided to leave the program in the middle of a conference title race. Points may be hard to come by in this matchup, especially for the RedHawks. Taking over for Finn will be Henry Hesson, who simply hasn’t proven to be much of an asset at the quarterback position in his limited time under center. He was given the start last week against Finn’s former team and proceeded to complete just 28.9% of his passes for 147 yards, 0 touchdowns, 3 interceptions and 4 turnover-worthy plays. Prior to that, he completed just 44.4% of his 18 pass attempts against UNLV — although he was able to have some success against FCS Lindenwood.

Without much of a passing attack, Miami figures to be fairly one-dimensional offensively. The RedHawks will likely keep the ball on the ground for a majority of the game, which plays right into the strength of Buffalo’s defense. The Bulls yield fewer than 3.5 yards per attempt this season and rank eighth in PPA per rush outside of garbage time since Week 8. They also rank top-25 in standard downs PPA and 10th in points per quality drive allowed in that span. On the other side of the ball, Buffalo has started to fall off offensively, ranking outside the top 125 in PPA per play and points per quality drive. The Bulls haven’t been able to establish a ground game, so it’s hard to trust them to march up and down the field against a solid Miami defense that held arguably the 2 best MAC quarterbacks in check over the last 2 weeks. Buffalo QB Ta’Quan Roberson is a walking turnover, so don’t be surprised if the RedHawks continue to generate havoc in this matchup. Frankly, unless you’re someone that absolutely loves ugly football, this game may be tough to watch. I’ll lean to the under without much conviction, as it wouldn’t surprise me if a special teams or defensive touchdown pushed this game over the total.

Miami (OH) vs Buffalo prediction: Under 40.5 (-110) at the time of publishing. Playable to 39. 

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7:30 PM ET
Tomorrow
ESPN
Louisiana Ragin' Cajuns
Arkansas State Red Wolves
UL Lafayette
Arkansas State
Point Spread Pick
Arkansas State -2.5(-115)

The Louisiana Ragin’ Cajuns travel to meet the Arkansas State Red Wolves in Jonesboro in the standalone game Thursday night. Both of these teams need victories, as they each try to keep their hopes alive for a bowl game. Those extra weeks of practice, and paydays for a bowl, are important to these smaller programs. Louisiana has rebounded from a 2-6 record to win at South Alabama and home to Texas State, getting back into the mix for a bowl. It has scored 36.5 PPG in the past two games, and the offense is good for 31 or more points in four of the past seven outings. They’re 4-2 ATS in the past six games, too.

Ark State has two chances to get a sixth win, punching its ticket to the postseason. It lost to Southern Miss last week, but that halted a four-game win streak. And, Ark State has covered five in a row. The Red Wolves are looking to exorcise some demons against the Ragin’ Cajuns, as Louisiana has won six of the past seven games, while holding a 4-3 ATS edge in that span. Louisiana has scored 27 or more points in each of those six wins, too, so it won’t be easy for the Red Wolves. But, Arkansas State is playing much better football lately, and it should finally be able to get over the hump.

Louisiana vs Arkansas State prediction: Arkansas State -2.5 (-110) available at time of publishing. Playable to -4.

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8:00 PM ET
Fri Nov 21
ESPN
Florida State Seminoles
NC State Wolfpack
Florida State
NC State
Point Spread Pick
NC State +4.5(-110)

The Florida State Seminoles hit the road for Raleigh on Friday night, and this battle against NC State will come with bowl eligibility for the winner. Both teams enter with five victories, one short of bowl eligibility. FSU has had its issues on the road this season. It all started with a stunning 46-38 loss in overtime at Virginia, and the season has spiraled from that point. It is 0-3 straight up (SU) and against the spread (ATS) in three game away from home, including a 20-13 loss at Stanford on Oct. 18 as a 17.5-point favorite, and a 24-10 loss at Clemson in the most recent trip on Nov. 8. That’s just 11.5 PPG scored on offense, with 22.0 PPG allowed on defense.

For NC State, it was humbled 41-7 at Miami last Saturday, a disappointing result after two weeks off following a massive 48-36 win in Raleigh against previously unbeaten Georgia Tech on Nov. 1 as a 5.5-point underdog. Still, NC State is just 1-3 SU and ATS in the past four games, but at home it is 4-1 SU, and 3-1 ATS in the past four. Florida State hasn’t shown an ability to win on the road, so let’s keep rolling with the opponent in those spots, especially since the Wolfpack are catching points at home. NC State is 5-2 ATS in the past seven in the series, too, winning each of the past three meetings in Raleigh since Nov. 3, 2018.

Florida State vs NC State prediction: NC State +4.5 (-110) available at time of publishing. Playable to +3.5.

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10:30 PM ET
Fri Nov 21
FS1
Hawaii Rainbow Warriors
UNLV Rebels
Hawaii
UNLV
Point Spread Pick
Hawaii +3.0(-115)

San Diego State is currently in the driver seat in the Mountain West, but the second spot in the conference title game is still up for grabs. Two of the teams competing for that spot are the Hawaii Rainbow Warriors and the UNLV Runnin’ Rebels, both of whom sit at 4-2 in conference play ahead of their matchup on Friday night. Due to the lack of tiebreakers, both of these teams have to win out to have a chance to play for a conference title – assuming the Aztecs also win out.

The Rainbow Warriors have greatly exceeded expectations this season, especially in conference play. Each of their 4 conference wins came when they were in the underdog role, with a 5th cover in the 2-point loss to Fresno back in September. UNLV, on the other hand, has been all over the place. The Rebels are in the midst of a 2-game winning streak after their 2-game losing streak, but they’ve failed to cover in 4 of their last 5 overall. Three of those 4 non-covers were in the favorite role. When you peel back the curtain even further, you will notice that UNLV hasn’t beaten anyone of note. The Rebels lost to the 2 best conference opponents they played and haven’t beaten a single Mountain West team with a winning record. In fact, they haven’t beaten any team with a winning record this year (at the time of writing, ahead of midweek MACtion). 

UNLV’s struggles against good competition stem from its very poor defense. It ranks 114th in scoring, 130th in total defense, and 132nd in yards per play, and opponents typically find the end zone against this unit once crossing into the red zone more often than not. That will likely spell trouble against the 3rd-most efficient red zone offense in the country in Hawaii. 

A win over the top team in the conference on November 8 restored Hawaii’s chances in the Mountain West, so the Rainbow Warriors should be fired up for this trip to the mainland following a bye that UNLV did not share last week. With a rest and preparation advantage, as well as a defensive advantage, give me Hawaii with that ever-appealing + next to its price. 

Hawaii vs UNLV prediction: Hawaii +3 (-115) at the time of publishing. Playable to +2. 

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12:00 PM ET
Sat Nov 22
ACC
Delaware Fightin' Blue Hens
Wake Forest Demon Deacons
Delaware
Wake Forest
Game Totals Pick
Over 51.5(-110)

The Wake Forest Demon Deacons have had a solid year in the ACC up to this date. They will get a break from conference action this week when they go head-to-head against the Delaware Blue Hens out of Conference USA. Wake Forest has won five of their last six games. They won their last game 28-12 against North Carolina. The offense looked good against a North Carolina team that is starting to find their footing defensively. Wake Forest ran the ball 39 times for 223 and 3 touchdowns, and quarterback Robby Ashford threw for another 191 yards and 1 touchdown. Delaware has a record of 5-5 this season, and they will be looking to bounce back from a 26-23 loss against Sam Houston last week. Quarterback Nick Minicucci threw for 338 yards and 1 touchdown in this game, but the Blue Hens could not slow down Sam Houston’s running game, allowing 139 yards rushing and 2 touchdowns.

 

Delaware has had competition this season against a Power Four school. Earlier this season they fell short against Colorado 31-7. Following the loss to Colorado back in the beginning of September, Delaware’s offense has scored 23 or more points in each game. Delaware’s offense is powered by one of the top passers in college football, Nick Minicucci. Minicucci is second in all of college football with 3063 yards passing this season. His favorite targets this season have been Sean Wilson and Kyre Duplessis, who have combined for 1353 yards receiving and 7 touchdowns. Wake Forest’s running game should be able to pick up where it left off, and if the Blue Hens’ defense plays like they did against Sam Houston, should be able to break loose for a couple long runs. Wake Forest should be able to take this game, but I think the Delaware offense does enough to push this game over.

 

Over 51.5 is available at the time of publishing. Playable at that number.

Vote on who will win!

12:00 PM ET
Sat Nov 22
FS1
Kansas Jayhawks
Iowa State Cyclones
Kansas
Iowa State
Point Spread Pick
Kansas +4.0(-110)

A midwestern, Big 12 matchup is set for this Saturday when the Kansas Jayhawks take on the Iowa State Cyclones. Kansas has a record of 5-5 this season and a conference record of 3-4. The Jayhawks have lost three of their last four games, including their last loss against Arizona 24-20. Quarterback Jalon Daniels led Kansas in passing and rushing yards. He threw for 199 yards and 1 touchdown, and he also ran for 74 yards and 1 touchdown. Iowa State has a record this season of 6-4 and a conference record of 3-4. The Cyclones were able to break a four game losing streak last game with a 20-17 win against TCU. Quarterback Rocco Becht was not his best, throwing for only 111 yards and 2 interceptions, but Iowa State was able to pull ahead late thanks to a punt return for a touchdown late in the 4th quarter. 

 

Both of these teams have fallen below expectations for this season. Iowa State was eyeing a Big 12 championship at the beginning of the season, and Kansas was looking to make more improvements from their disappointing 2024 season. As these teams are both looking to even up their conference records, I’m looking at the level of quarterback play from each team. Kansas is led by senior quarterback Jalon Daniels. Daniels has again put up a stellar season, throwing for 2190 yards, 21 touchdowns and only 3 interceptions. Daniels has been dynamic on offense, limited turnovers, and has looked great in recent games. Iowa State’s quarterback, Rocco Becht, has been the opposite. He has thrown for 2230 yards, 12 touchdowns, and 9 interceptions. Becht has been playing his worst football in recent games. Becht has thrown 7 interceptions in his last four games. Neither defense has played well, with both units allowing more than 28 points per game in their last five games, but right now I am trusting Daniels more with the football than I am Becht.

 

Kansas +4 is available at the time of publishing. Playable at that number.

12:00 PM ET
Sat Nov 22
BTN
Minnesota Golden Gophers
Northwestern Wildcats
Minnesota
Northwestern
Point Spread Pick
Northwestern -3.5(-110)

The Minnesota Golden Gophers will travel this Saturday to take on the Northwestern Wildcats in a Big 10 matchup. The Gophers have a record of 6-4, but all four losses have come on the road. They will try to get their first road win of the season against Northwestern. Minnesota’s last loss came at the hands of Oregon 42-13. Quarterback Drake Lindsey threw for 138 yards and 1 touchdown, but the Gophers defense allowed a recently struggling Oregon offense to explode for 42 points. Like Oregon, Northwestern will be looking to turn around their recent struggles. The Wildcats have lost their last three games, including their last loss 24-22 against Michigan. Northwestern led this game late, but they could not hold on as Michigan took the lead on a late field goal. Northwestern’s defense did force two interceptions, and will be looking to create more turnovers this week against Minnesota.

 

This should be a good opportunity where Northwestern’s defense can carry them to victory. Northwestern’s defense has been their strength all season, ranking in the top half of the FBS in yards and points allowed per game. They flexed their muscles against Michigan, but came up just short. Now they get a second chance on their home field against a Minnesota team that has really struggled away from home. The Gophers have only averaged 8.3 points per game when playing on the road this season. Against Oregon, they were able to break an 11-quarter drought where their offense was left without a touchdown. The defense has also been Minnesota’s strength, but they have also shown inconsistencies on the road, allowing over 40 points scored in all of their last three road games. Quarterback Preston Stone has seemingly done just enough all season, and he should have the opportunity to get enough things done against a Gophers defense that ranks 64th against the pass. I like for Northwestern to break their losing streak against a Minnesota team that has not shown any life away from their home field.

 

Northwestern -3.5 is available at the time of publishing. Playable at that number.

12:00 PM ET
Sat Nov 22
FOX
Rutgers Scarlet Knights
Ohio State Buckeyes
Rutgers
Ohio State
Game Totals Pick
Over 55.5(-110)

The Rutgers Scarlet Knights hit the road for Columbus to battle the top-ranked Ohio State Buckeyes at The Horseshoe. It’s the penultimate game of the season for both teams. Rutgers has five victories this season, and it needs a win against the Buckeyes, or home against Penn State next Saturday, to qualify for a bowl game. Rutgers has won two of the past three games to keep its postseason hopes alive, while also going 2-1 against the spread (ATS). The Under has cashed in each of the past three games, too, while going 4-1 in the past five outings. The Scarlet Knights have scored 19 or fewer points in three of the past five games.

For the Buckeyes, they’ve allowed 10 or more points in three straight games, but they’re still allowed 75 points all season, or 7.5 points per game (PPG). The Under is 3-2 in the past five games, and 5-3 across the past eight outings. However, at home, the Over is 3-0 in the past three conference games at the Horseshoe, and 4-1 in the past five home games dating back to Sept. 6. Ohio State has dominated this series since Rutgers joined the Big Ten, winning all 10 meetings since Oct. 18, 2014, while the Over has connected in five straight outings. Ohio State has scored 49 or more points in nine of the past 10 meetings, with the lone exception a 35-16 victory in the most recent battle on Nov. 4, 2023 in Piscataway. Go high, and feel confident in doing so.

Over 55.5 (-110) at time of publishing. Playable to 56.5.

Vote on who will win!

12:00 PM ET
Sat Nov 22
SECN
Samford Bulldogs - NCAAF
Texas A&M Aggies
Samford
Texas A&M
Point Spread Pick
Samford +55.5(-110)

Anytime a team is laying north of 50 points in mid-November, bettors should immediately ask a simple question: What is the motivation for the favorite to run up the score? In this case, Texas A&M has every reason not to. The Aggies are days away from the biggest game of their season — a Thanksgiving weekend showdown in Austin against Texas. That matchup is not just about rivalry pride; it’s effectively A&M’s ticket to Atlanta. If the Aggies go into Austin and beat the Longhorns, they’ll position themselves to play for the SEC Championship and perhaps even grab a seat inside the top four of the College Football Playoff. Everything they’ve worked for funnels directly into next weekend.

Which leads us to this: What benefit is there for A&M to empty the tank against Samford? The honest answer is none. The Bulldogs are essentially a live-action scrimmage for the Aggies — a tune-up at best. There is no incentive to put anything meaningful on tape, risk injuries to starters, or burn high-value plays that Texas could scout. This is a pure manage-and-move-on spot for the home side. And that opens multiple pathways for Samford to cover. First, A&M has to actually score 56 just to push this number to the threshold. That’s no small ask, even against an FCS opponent, especially when the second team — and likely the third team — will play the majority of the second half. A&M may get into the 40’s, maybe the low 50’s at most, but surpassing 55.5 requires both aggression and intention, neither of which align with where the Aggies are mentally right now. Second, if Samford even scratches the scoreboard — a field goal, a broken play, a late touchdown against A&M’s deep reserves — the Aggies would need close to 60 to beat this number. That’s probably not going to happen here. There is no reason for the Aggies to get cute.

Samford vs. Texas A&M prediction: Samford +55.5 (-110) available at time of publishing. Playable at the number.

12:45 PM ET
Sat Nov 22
SECN
Charlotte 49ers
Georgia Bulldogs
Charlotte
Georgia
Point Spread Pick
Georgia -43.5(-110)

Georgia enters this matchup looking every bit like the best team in the nation, and this spot against Charlotte sets up as another opportunity for the Bulldogs to show how far ahead they are of most opponents. Last week’s 35–10 dismantling of Texas in Athens was another indication that this team is hitting its stride, particularly on the defensive side of the ball, where they continue to generate short fields and even direct scoring opportunities. The week prior, they handled Mississippi State by 21 on the road, controlling every phase from start to finish.

Laying this many points is never comfortable, and Georgia has no incentive to run up the score unnecessarily. But the danger with fading the Bulldogs comes from the fact that they score in all three phases. Their defense pressures every snap, creates turnovers, and often converts those into points. Their special teams consistently flip the field and have the talent to break a return at any moment. When you combine that with an offense that’s improving weekly and a coaching staff emphasizing continued growth, the margin can escalate naturally. Charlotte simply doesn’t have the personnel to hold up for four quarters, and Georgia’s depth ensures the level rarely drops when backups rotate in. Even without forcing the issue, Georgia can get into the high 40s, and if the defense sets up or produces a score or two, covering becomes very realistic.

Charlotte 49ers vs Georgia Bulldogs prediction: Bulldogs -43.5 (-110) available at time of publishing. Playable to -44.

1:00 PM ET
Sat Nov 22
ESPN+
Washington State Cougars
James Madison Dukes
Washington State
James Madison
Point Spread Pick
Washington State +13.5(-105)

James Madison enters this matchup riding a wave of momentum and national recognition. At 9–1 overall and perfect at home, the Dukes have put themselves squarely in position to become the potential Group of Five representative in the College Football Playoff if the AAC continues cannibalizing itself. They’re 7–3 against the spread, consistent, efficient, and well-coached—everything you want from a team pushing for a major postseason berth. But that success brings pressure, and this is the part of the season where teams in JMU’s position can tighten up. With their division already clinched and a season-ending showdown with Coastal Carolina on deck, the mental landscape becomes complicated.

Washington State, meanwhile, is the classic volatility team. Their ceiling is high, and their floor is bottomless. They lost to an Oregon State team that hadn’t beaten an FBS opponent all year. They gave up 59 to North Texas. They narrowly avoided disaster against Idaho. Yet they also pushed Ole Miss to the brink in Oxford, nearly won at Virginia, and blasted San Diego State 36–13. You never know which version is showing up, but when the Cougars are engaged, they’re a genuine threat. The number offered here suggests the dangerous iteration of the Cougs show up. Upset potential is high here, grab the points.

Washington State vs James Madison prediction: Washington State +13.5 (-105) available at time of publishing. Playable to +13.

Game Totals Pick
Under 42.0(-110)

The total ties directly into the side. If Washington State covers, it likely happens because they dictate pace and keep James Madison from pulling the game into the high-scoring range. WSU’s competitive outings typically land in the low-40s. We’ve already seen James Madison get pulled into grind-it-out games, such as the rock fight with Georgia State that finished 14-7. If this becomes a possession-by-possession battle—which is the exact script WSU needs to be a problem for the Dukes —then the under 42 makes sense.

Matching the side and total gives a clear correlated angle: a tight, controlled, lower-tempo game that keeps the Cougars within reach and keeps the scoreboard constrained. These two plays can be combined at certain outfits as a correlated parlay and that would be recommended. Under is the move here.

Washington State vs James Madison prediction: Under 42 (-110) available at time of publishing. Playable to the number.

2:00 PM ET
Sat Nov 22
SECN+
Eastern Illinois Panthers
Alabama Crimson Tide
Eastern Illinois
Alabama
Point Spread Pick
TBD(-110)

Alabama finds itself in an unusual spot this week. Just seven days ago, the Tide were the most heavily-backed side on the college football board as a six-point home favorite against Oklahoma. Not only did they fail to cover—they lost outright, 23–21. That result dramatically changes the market’s perception heading into this matchup with Eastern Illinois. Suddenly, bettors will be hesitant to lay a big number with Alabama, and as a result, we’re getting the Tide cheaper than we would’ve had they handled their business last week.

This becomes an ideal bounce-back situation. With Auburn looming and playoff hopes now extremely fragile, Kalen DeBoer has every incentive to sharpen his team and eliminate the sloppiness that cost them against the Sooners. Alabama rarely stacks poor performances back-to-back, and this is exactly the type of opponent they can use to reset their rhythm, establish physical dominance, and get their confidence in order before the Iron Bowl. Eastern Illinois simply doesn’t have the personnel to keep Alabama uncomfortable for four quarters, and emotionally, the Tide should be fully locked in. Last week’s loss creates urgency, and a focused Alabama team laying a discounted number is a spot worth playing. This is a classic “take it out on the opponent” setting.

Eastern Illinois vs Alabama prediction: Alabama minus the points. Point spread to be determined.

3:30 PM ET
Sat Nov 22
ACCN
Duke Blue Devils
North Carolina Tar Heels
Duke
North Carolina
Money Line Pick
North Carolina Win(+210)

There’s an emotional contrast between these two teams that shapes this matchup far more than the box scores do. Duke has been quietly crafting a narrative—maybe they could slip into Charlotte and perhaps inadverently derail the ACC’s playoff hopes, while doing so. Then came last week. Virginia didn’t just beat them; the Cavaliers effectively extinguished the Blue Devils’ entire dream scenario. This is a quintessential letdown spot.

North Carolina arrives from the opposite direction—backed into a corner, but still dangerous. The Bill Belichick hire was supposed to stabilize the program and elevate the Tar Heels, yet the season has unraveled into a frustrating 4–6. They lack a signature win, momentum has been elusive, and bowl eligibility now hangs by a thread. That’s precisely why this game looms so large. In many ways, this is their bowl game. A rivalry setting, a chance to salvage pride, and a must-win scenario to keep bowl hopes alive all collide here. Duke is laying a modest number despite facing a losing team on the road, suggesting oddsmakers aren’t convinced the Blue Devils will deliver their best version after last week’s emotional drain. And Duke is exactly the type of team that can play down to an opponent’s level when the stakes suddenly disappear. That makes the upside of the moneyline worth pursuing.

Duke vs North Carolina prediction: North Carolina +210 (Money Line) available at time of publishing. Playable to the number.

Vote on who will win!

3:30 PM ET
Sat Nov 22
ESPN+
East Carolina Pirates- NCAAF
UTSA Roadrunners
East Carolina
UTSA
Money Line Pick
Texas San Antonio Win(+120)

While there are plenty of games that should captivate college football fans across the nation on Saturday, one of the more under the radar games that should have your attention is a big time contest in the AAC, where the East Carolina Pirates will visit the UTSA Roadrunners in a compelling clash that should produce plenty of fireworks. This is one of the better spots of the Week 13 slate, and I intend to take advantage of it by backing the Roadrunners to win as short underdogs at home.

On one side, East Carolina is in the midst of a very good run of form and the Pirates are coming off one of their biggest wins in years against Memphis in a game that thrust them back into the AAC title race and potentially even an outside shot at the College Football Playoff if a couple of dominoes fall in the Sun Belt and Mountain West. East Carolina’s offense has steadily improved as the season has gone on, as quarterback Katin Houser has now thrown for nearly 3,000 yards while tossing 15 touchdowns to just 5 interceptions. However, this is a brutal road trip for a Pirates team that has struggled away from home against quality competition this season, and has had trouble with UTSA in the Alamodome in years past. Given the enormity of last week’s win, don’t be surprised if East Carolina comes out a bit slow in what could be a flat spot for Blake Harrell’s team. 

As for the hosts, UTSA has been an up-and-down bunch all season long, but the Roadrunners are likely a bit better than their record given how a few of their results look in hindsight. Historically, Jeff Traylor has been an excellent head coach against the spread in November and his team certainly looks like they’ve turned a corner offensively in recent weeks, with Owen McCown and company rolling through the likes of Tulane and Charlotte at home. Where UTSA has gotten into trouble has been against psychical and fast teams on the road (USF and North Texas come to mind), but that’s not the situation that they’ll see in this one. The Roadrunners pass defense is still an issue but they should be able to slow down the East Carolina ground attack and keep the Pirates behind the chains at points in this contest. And because they play at an extremely fast pace, East Carolina has not shown that it can consistently grind out close wins, particularly away from home. Given the fact that I expect this one to be a close contest from start to finish, there’s some inherent value on the home underdog on Saturday. 

East Carolina vs UTSA prediction: UTSA ML (+120) available at time of publishing. Playable to +110.

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3:30 PM ET
Sat Nov 22
ESPN
Kentucky Wildcats
Vanderbilt Commodores
Kentucky
Vanderbilt
Point Spread Pick
Vanderbilt -9.5(-110)

The Vanderbilt Commodores needed a week off after playing LSU, Missouri, Texas, and Auburn all in a row – each of those contests being decided by 1 score. At 8-2, the Commodores still have an outside chance at a College Football Playoff berth, but they must win both of their remaining games to have a shot – starting with a home date against Kentucky on Saturday. The Wildcats have surprisingly won 3 games in a row, including a win at Auburn that sent Hugh Freeze packing and a 38-7 domination of Florida at home in Lexington. 

Despite its win at Auburn, Kentucky hasn’t been very good on the road. In fact, the Wildcats have scored just 37 points in 3 true road games this year, which makes it hard to trust them in this matchup. Vanderbilt’s offense remains one of the most potent in the sport, sitting 4th in yards per play and third-down conversion rate on the season, as well as top-20 in PPA per play and points per quality drive since Week 8 despite playing a strong assortment of defenses in that span. 

Moreover, the Commodores have one of the strongest red-zone offenses in the country, especially when playing at home. Not only do they score on over 96% of red zone trips at home, but they have the 2nd-highest red-zone touchdown rate in the country – converting 37 of their 47 total red-zone trips into touchdowns. Kentucky is nowhere close to this level of red-zone production, converting fewer than 67% of road red-zone trips into any sort of points.

Kentucky has covered in 4 of its last 5 games, but the Wildcats have seen just 1 above-average offense in that span – the Tennesse Volunteers. Coincidentally, Kentucky did not cover in that game. In fact, the Wildcats surrendered 56 points in that one. Meanwhile, Vanderbilt has been an ATS ATM this year at 7-2-1, including 3 straight covers as a home favorite. With everything to play for, look for Vanderbilt to benefit from extra rest and preparation and win this one by double digits – setting a perfect scene for an in-state showdown against Tennessee in the final week of the regular season to decide its postseason fate.

Kentucky vs Vanderbilt prediction: Vanderbilt Commodores -9.5 (-110) at the time of publishing. Playable to -10. 

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4:15 PM ET
Sat Nov 22
SEC Network
Coastal Carolina Chanticleers
South Carolina Gamecocks
Coastal Carolina
South Carolina
Point Spread Pick
South Carolina -23.5(-115)

It’s been a rough year for the South Carolina Gamecocks, who have lost 5 straight and 7 of their last 8 after Saturday’s cataclysmic meltdown in College Station. South Carolina held a 30-3 lead at halftime over No. 3 Texas A&M, but forgot to come out of the locker room after the intermission. The Gamecocks never scored another point and eventually lost the game 31-30. 

Objectively, the Gamecocks have had a brutal schedule, as 6 of their last 7 opponents were all ranked at the time of kick-off. Going one step further, each of their last 4 opponents are squarely in the College Football Playoff picture among the top-12 teams in the country. However, that won’t be the case this week, as the Gamecocks will benefit from the classic late-season SEC buy-game when they host the Coastal Carolina Chanticleers on Saturday (even as an SEC fan, I hope these go away with the new 9-game conference schedule) .

Some will argue that this will be a flat spot for South Carolina off the heartbreak at Texas A&M, especially considering the Gamecocks won’t make a bowl and have their rival Clemson on deck. However, I disagree with that sentiment and would argue the Gamecocks will use this as an opportunity to unleash frustration on an inferior opponent. It’s certainly a massive number to lay with a team that has not instilled much trust in bettors alike, but the talent gap in this matchup is massive – and there is certainly nothing to write home about this Coastal Carolina defense. The ‘Chants are outside the top 100 in yards per play allowed this year, and more recently, they are 75th in points allowed per quality drive and 98th in PPA per play since Week 8. Look for the Gamecocks to finally have a complete performance in this one. 

Coastal Carolina vs South Carolina prediction: South Carolina Gamecocks -23.5 (-115) at the time of publishing. Playable to -24.

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7:00 PM ET
Sat Nov 22
ESPN
Pittsburgh Panthers
Georgia Tech Yellow Jackets
Pittsburgh
Georgia Tech
Money Line Pick
Georgia Tech Win(-128)

Georgia Tech’s ACC Championship hopes are in the balance this weekend when the 9-1 Yellow Jackets host the 7-3 Pitt Panthers in Atlanta. The Jackets barely – and I mean barely – survived on the road at Boston College last week. They needed 628 total yards and a 19-point 4th quarter to win the game 36-34, as a first-half fumble and missed field goal suppressed Georgia Tech’s scoring before the intermission. 

As for Pitt, the Panthers managed to keep it close against Notre Dame for all of about 6 minutes before the wheels fell off when Mason Heintschel threw a pick 6 to put the Irish up 14 – a lead from which they never looked back. Coach Pat Narduzzi won’t be mad though, right? Like he said, the Notre Dame game didn’t matter, even if the Panthers lost by 100. 

Georgia Tech’s defense is extremely worrisome. The Yellow Jackets are outside the top 70 in scoring and outside the top 100 in total defense, which leaves them exposed every single week. Look no further than last week, when the Jackets surrendered more than 30 points and 500 yards to a Boston College offense that had not surpassed 24 points since Week 2. However, I’m still siding with Tech in this one, mostly because of QB Haynes King.

King has been one of the most reliable QBs in the country this year. He has just 2 interceptions, and you could argue they weren’t his fault considering he has 0 turnover-worthy plays according to PFF. King also sits top-10 in completion percentage and has been sacked just 8 times this year – mostly due to his dynamism as a runner. The GT signal-caller leads the team with over 800 rushing yards, has ripped off 25 10+ yard runs, and leads the country in non-RB rushing touchdowns this season.

As a team, Tech averages less than 1 giveaway per game against FBS opponents, which is tied for 12th nationally. Meanwhile, Pitt ranks 114th, averaging nearly 2 giveaways per game. Narduzzi made the switch from Eli Holstein to Heintschel in an attempt to find stability at the QB position, but Heintschel has been just as careless with the ball as his predecessor – posting 6 interceptions and 13 turnover-worthy plays in 6 starts. Five of those interceptions and 7 of those turnover-worthy plays came on the road. 

Being the veteran home team with the more trustworthy QB, I like the Yellow Jackets to get the win in their final ACC game and punch their ticket to the conference championship in Charlotte – but I’m wary of laying points with them after their defensive showing last week. Hopefully they were just looking ahead to this game? 

Pitt vs Georgia Tech prediction: Georgia Tech Yellow Jackets ML (-128) available at the time of publishing. Playable to -150.

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Game Totals Pick
Over 61.5(-115)

It’s hard to like anything other than points in a Georgia Tech game at this point. While the Yellow Jackets are very run heavy, they create big plays at a top-20 rate and have been fairly effective at getting to and putting up points in the red zone – though their red-zone touchdown rate could be a bit better. The same could be said for the Pitt Panthers, who are 5th in red-zone trips but 106th in touchdown rate once crossing the opposing 20-yard line. Like Tech, the Panthers are top-40 in plays of at least 20 yards, which of course lends right into their propensity to find the red zone. 

For as efficient as Pitt has been defensively at times this season, the Panthers really struggle with their backs against the wall. Of the 26 red zone trips allowed, opponents have punched it into the end zone 18 times against the Panthers, which makes me think the Yellow Jackets will have success finishing drives with touchdowns so long as they can consistently get deep into Pitt territory. For what it’s worth, every capable offense the Panthers have played dropped at least 30 on them. On the other side, Georgia Tech’s defensive issues are household knowledge at this point. The Yellow Jackets, more likely than not, are going to give up a few scores here. I’m expecting a shootout. 

Pitt vs Georgia Tech prediction: Over 61.5 (-115) at the time of publishing. Playable to 62.5.

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Vote on who will win!

7:30 PM ET
Sat Nov 22
ESPNU
North Texas Mean Green
Rice Owls
North Texas
Rice
Game Totals Pick
Over 55.0(-110)

The North Texas Mean Green head from Denton to Houston to battle the Rice Owls in Houston in an intra-Texas American Conference battle. UNT is looking to keep it possible, but faint, hopes alive for spot in the College Football Playoff, too. The Mean Green have been one of the most potent offenses in the nation, too, going for 489.6 total yards and 307.3 passing yards per game, both ranking sixth in the country. It also has 182.3 rushing yards per game, 40th in the country, while ranking No. 1 overall with 45.3 PPG. Defensively, North Texas does struggle to stop the run, allowing 202.7 yards per game, and that’s been an Achilles heel.

For Rice, it cashed the Under in a 24-17 win over UAB last time out, but the Over has cashed in three of the past four games, with the defense allowing 27 or more points in four of the past five outings. That’s ominous with North Texas looming on the horizon. The Owls really struggle offensively, although it has posted 211.1 yards per game, ranking 18th in the country, and that’s bad news for UNT’s struggling rushing defense. But, Rice allows 27.9 PPG, ranking 89th in the country, and that means North Texas should come close to its season average in points. If so, the Over should be a slam-dunk play in the Space City.

Over 55.5 (-110) at time of publishing. Playable to 57.5.

Vote on who will win!

7:30 PM ET
Sat Nov 22
ABC
Tennessee Volunteers
Florida Gators
Tennessee
Florida
Game Totals Pick
Under 57.0(-110)

The Under is directly tied to the Gators’ winning formula. Florida cannot afford a shootout. Their path is built on defense, controlled possessions, and forcing Tennessee into long drives. If they get the early lead and lean into their pass rush and run defense, this game becomes a grind. Florida winning correlates strongly with a game in the 40’s or low 50’s — not one pushing toward 60.

If Florida wins, it won’t be a track meet. They’ll rely on their defensive front to disrupt Tennessee, shorten possessions, and keep this game on their terms. They will also be relying on the Florida faithful to be disruptive in The Swamp. If Tennessee is able to turn this into a shootout, Florida is in trouble as they likely can’t hold serve. When they came close to beating Georgia, it was a lower-scoring affair. When they beat Texas, the game was defined by field position and optimizing points. We are rolling with the Gators to win and thus the Under is conducive to back here, as well.

Tennessee vs Florida prediction: Under 57 (-110) available at time of publishing. Playable to the number.

Money Line Pick
Florida Win(+165)

Everything about this matchup points to Florida being live. When a ranked Tennessee team travels into a hostile environment and is still only laying a short line to a 3–7 opponent, that tells you the market isn’t buying the Vols. And they shouldn’t. Tennessee has been wildly inconsistent and has repeatedly shown defensive vulnerability, giving up 33 to Oklahoma, 34 to Kentucky, 37 to Alabama, 31 to Arkansas, and 34 to Mississippi State. That kind of performance profile is the exact opposite of what you want when you’re laying road chalk.

Florida, meanwhile, has had a disappointing season in the standings, but they’ve been a different animal at home. The Gators already beat Texas in Gainesville, sit at 3–1 in the Swamp, and easily could be 4–0 if not for letting the USF game slip away late. At home, this is a tough, physical defense with a pass rush that can create chaos. They’ve also won seven of the last ten vs. Tennessee, and rivalry familiarity matters in a matchup where motivation tilts heavily toward the underdog: this is Florida’s de facto bowl game. A loss eliminates them from bowl contention entirely; a win keeps hope alive. Tennessee has nothing truly tangible on the line — no playoff path, no major stakes — and when a ranked team goes on the road in that kind of scenario, lack of urgency becomes a real factor. If the Vols start slow or let Florida dictate the tempo early, they are absolutely vulnerable to an upset. We’re backing UF to pull it off.

Tennessee vs Florida prediction: Florida +165 (Money Line) available at time of publishing. Playable at number.

Vote on who will win!

7:45 PM ET
Sat Nov 22
SECN
Western Kentucky Hilltoppers
LSU Tigers
Western Kentucky
LSU
Point Spread Pick
Western Kentucky +22.5(-110)

This is all about LSU’s mentality and motivation, or lack thereof. The Tigers have completely unraveled this season, and the program feels like it’s stuck in neutral. They still don’t know who their next head coach will be, players are already thinking about the offseason, and the team is essentially going through the motions at this point. That is not the kind of mindset you want laying more than three touchdowns.

Western Kentucky, meanwhile, comes in at 8–2 with real momentum and something to play for. The Hilltoppers see this game as an opportunity—these chances don’t come around often for a Group of Five team. They get to walk into Tiger Stadium against a brand-name SEC opponent that clearly isn’t invested in finishing the season strong. Western Kentucky has every reason to treat this as their statement game before their finale against Jacksonville State. When you put a focused, hungry 8–2 team against a checked-out roster with no direction, this many points becomes hard to ignore. LSU may still win on raw talent, but covering this kind of number requires intensity, attention to detail, and motivation—none of which LSU has shown. Western Kentucky should compete from start to finish.

Western Kentucky vs LSU prediction: Western Kentucky +22.5 (-110) available at time of publishing. Playable to +22.

10:30 PM ET
Sat Nov 22
FS1
San Jose State Spartans
San Diego State Aztecs
San Jose State
San Diego State
Point Spread PickBest Bet
San Diego State Win -11.5(-110)

The San Jose State Spartans hit the road for Snapdragon Stadium to battle the first-place San Diego State Aztecs, who can clinch a spot in the Mountain West Conference championship game with a win. Don’t expect San Diego State to take its foot off the gas and suffered a letdown. San Diego State bounced back nicely in the rain last week against Boise State, winning 17-7, a good win after a debacle in the islands, when it lost 38-6 at Hawaii. The Aztecs are still 7-1 straight up (SU) in the past eight games, and they’re also 7-1 against the spread (ATS) in the span, with the only non-cover in the islands. The Under is 4-0 in the past four games, too, as the defense has been on point for San Diego State. It has allowed 10 or fewer points in four of the past five games, and it has three shutout wins, while allowing 10 or fewer points on seven occasions.

The Spartans are no longer eligible for a bowl after losing their seventh game of the season at Nevada last week, 55-10. It has allowed 26 or more points in nine consecutive games, and San Jose State has dropped four of the past five games, while going 1-4 ATS, if you’re looking for a same-game parlay (SGP). But, San Jose State has scored just 13.0 PPG in the past two games, and against San Diego State, it won’t get much better. Look for a rout for the Aztecs, and go with the Under, too.

San Diego State -11.5 (-110) at time of publishing. Playable to -13.5.

10:30 PM ET
Sat Nov 22
CBSSN
Utah State Aggies
Fresno State Bulldogs
Utah State
Fresno State
Game Totals Pick
Under 51.0(-110)

The Utah State Aggies head to The Valley to battle the Fresno State Bulldogs for a key Mountain West Conference game on Saturday night. Utah State is reeling after coming up short in an upset bid at UNLV. It had several chances to win, and attain bowl eligibility, but Utah State had tremendous difficulties in the kicking game, helping it come up short. Utah State also blew a chance at a shot in the Mountain West Conference championship game, too. It needs a win at Fresno, or home to Boise State next Saturday, if it hopes to qualify for a bowl game. Utah State is winless in five games on the road this season, but it has covered three times.

Fresno State is very much in the mix for a conference title spot, especially thanks to a huge win at Boise State a couple of weeks ago. It is a game back of San Diego State for the top spot, while tied with four other teams in a logjam for second place at 4-2 in the league. Fresno State has won and covered the past two games, while the Under has cashed in three in a row, and five of the past six games. The Bulldogs have leaned on defense, allowing 23 or fewer points in six of the past seven games. The Aggies have cashed Under in three of the past four games, too. We’ll go low on the total in this important game.

Under 51.5 (-110) at time of publishing. Playable to 51.

Vote on who will win!

10:30 PM ET
Sat Nov 22
NBC
Washington Huskies
UCLA Bruins
Washington
UCLA
Point Spread PickBest Bet
Washington -10.0(-115)

Following a 49-13 win over Purdue, the 7-3 Washington Huskies will head to southern California to play the 3-7 UCLA Bruins. Meanwhile, the Bruins come into this game after being beat down by the Ohio State Buckeyes in Columbus. It was the 3rd straight loss for the Bruins, who were without starting QB Nico Iamaleava in the contest. Iamaleava participated in drills on Tuesday, so he could return from concussion on Saturday. However, regardless of his status, I like the Huskies in this battle of former Pac-12 foes. 

Washington certainly hasn’t fared well on the road this year, but not all road games are created equal in the Big Ten nowadays. The Huskies’ worst road performances were all in the central and eastern time zones, but they won’t leave the west coast for this one – which has to be a relief. While the Huskies haven’t been the most reliable ATS as a favorite either, I power rate them as 14-point favorites in this matchup. 

When you look at the numbers, it makes sense. The Bruins haven’t been good on either side of the ball of late. In fact, they are outside the top 100 in PPA per play and points per quality drive on both offense and defense. Compare that to Washington, who is top-35 offensively and top-20 defensively in the aforementioned metrics. Moreover, Washington has reached the red zone 14 more times than UCLA this year and boasts the 3rd-best red-zone touchdown rate nationally – punching it into the end zone on 33 of 42 trips across the opposing 20-yard line. That smells like trouble for Bruins, who rank 133rd in red-zone touchdowns allowed (33) and 135th in opposing red-zone touchdown rate (78.57%). Look for the Huskies to name their score and cruise to a win and cover.

Washington vs UCLA prediction: Washington Huskies -10 (-115) available at the time of publishing. Playable to -12.5.  

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College Football Picks This Week

With so many conferences and hundreds of matches played every weekend, the biggest test with any college football picks is unearthing those hidden gems. Here at Pickswise, that is exactly what we do. By focusing on the Power conferences and the Top-25 teams, along with a select number of other matches, our experts can focus on the key games and leave no stone unturned in our research. Pickswise is the home of free NCAAF picks, and we break down all of today’s college football action, with each pick coming with accompanying analysis, including all of the key stats, trends, and reasons for our pick.

Be sure to check back each week during the season for all of our top college football picks today.

Expert College Football Picks Against The Spread (ATS)

The most popular college football pick is against the spread (ATS). Against the spread betting isn’t about picking a winner of the football game, it’s about picking the team who will cover the spread.

Let’s say you bet your money that Team A covers the spread (wins by a certain amount of points), Michigan State -6.5 for example. Or that Team B will cover the spread (keep the game closer than oddsmakers expect), Ohio State +6.5. If Michigan State beat Ohio State 30-27, then Ohio State covers the spread, and underdog backers are cashing tickets with +6.5 on Ohio State.

Against-the-spread betting is extremely popular in football and that’s one of the main reasons why it’s one of the most popular college football picks on our site.

NCAA Football Today – Today’s NCAAF Picks

At Pickswise we cover all of the Power NCAA football today, with full game previews, picks, and betting analysis brought to you by our college football experts. A typical college football season runs from August to December and is preceded by the College Football Bowl Season and College Football Playoff, culminating in The College Football Playoff National Championship game in January.

When Do You Post Your College Football Picks

We post our college football picks for this weekend a couple of days before the scheduled match. We post our picks early enough so that you can digest the information, do your own research into the match, and make sure you get the best lines and odds for that particular pick. Like anything in sport, some things are unpredictable, and on occasion, we may choose to delay posting a pick if there is something like a key injury or likely conditions that could have an impact on the outcome of the match, or our pick itself. Check back leading up to the weekend every week throughout the season to see what NCAAF Picks we have for today.

Free Expert NCAAF Picks

All of our NCAAF picks are absolutely free, all season long. We have a team of expert NCAAF handicappers on hand to preview the very best of the Power conference or Top-25 ranked match, every week, all season long. Each of these previews comes with our experts’ NCAAF pick on the three main markets (Money Line, Spreads & Totals) with a full breakdown of why they like a particular side, as well as a confidence rating for each individual NCAAF pick. You can find every NCAAF pick throughout the season right here on the NCAAF Picks page, or check out our NCAAF Parlays for even more insight into betting better on NCAA Football this week.