Appalachian State Mountaineers

Appalachian State Mountaineers vs Charlotte 49ers Prediction, Odds and Picks for Friday, 08/29/25

Bank of America StadiumESPNU
Appalachian State
0-0
Appalachian State
Fri Aug 29
Charlotte
0-0
Charlotte

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Charlotte 49ers

Appalachian State vs Charlotte Pickswise Expert Predictions

Appalachian State Mountaineers
Game Totals Pick
Under 50.0(-110)

The Appalachian State Mountaineers and the Charlotte 49ers will start the season with a fun, neutral-site matchup on Friday night from Bank of America Stadium, the home of the Carolina Panthers, just down the highway from Charlotte’s campus. Both of these teams will be running fresh systems on both sides of the ball, as both head coaches and all of their coordinators are completely new at their respective programs this season. Tim Albin left his post at Ohio University after leading the Bobcats to their first MAC championship since the 1960s, while Dowell Loggains was previously the offensive coordinator at South Carolina and has never been a head coach.

In addition to the overhaul on both staffs, there is ample change throughout the roster, as App State and Charlotte are both outside the top 115 in returning production. In fact, neither team will have more than 43% returning production on either side of the ball. Close to 50 combined transfers will be on the 2-deep of these two rosters. Needless to say, it may take a few drives to a few quarters for these offenses to look somewhat cohesive. 

Both of these coaches love to deploy smash-mouth, pro-style offenses that are heavily predicated on the run. That should remain constant on Friday, and the clock should be running for a vast majority of this game because of it. Given the amount of new faces at both programs, in addition to the expectation that this will be a game heavily centered around the run, I like the Under most in this battle of G5 teams from North Carolina.

Appalachian State vs Charlotte prediction: Under 50.5 (-110) available at Fanatics at the time of publishing. Playable to 49.

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Charlotte 49ers
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Sam Avellone

Long-time suffering Browns fan born and raised in the greater Cleveland, Ohio area who now resides in SEC country. University of South Carolina alum. Sports handicapper for close to 10 years with a primary focus on NCAAB while enjoying NFL, PGA, NCAAF, NBA, and Soccer. For Sam Avellone media enquiries, please email contact@pickswise.com.
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