Arkansas Razorbacks vs LSU Tigers Prediction, Odds and Picks for Saturday, 11/15/25

The Arkansas Razorbacks have dropped 7 straight games while LSU is on a 1-4 stretch in their last 5. It’s a matchup of two SEC programs spiraling downhill featuring mid-season head coach firings. LSU managed just 9 points in the Tigers’ first game without Brian Kelly on the sideline, and the offense has been a problem altogether this season. The Tigers rank 134th in FBS in points per quality drive and rank 125th in rushing yards per game (101.0). 

While the 2025 season has gone about as poorly as any Arkansas fan could have imagined, the Razorbacks’ offense is much better than the 2-7 record shows for. Arkansas ranks top-15 in both passing success rate and rushing success rate. Furthermore, Arkansas ranks 9th in quality drive rate and has been excellent at finishing those quality drives, ranking 7th in red zone offense. The LSU offense isn’t built to pull away with a big lead, especially against a high-octane offense like the Razorbacks possess. I’ll take Arkansas to cover on the road.

Arkansas vs LSU prediction: Arkansas +6 (-110) available at time of publishing. Playable down to +5.5 (-110).