BYU Cougars vs Cincinnati Bearcats Prediction, Odds and Picks for Today, 11/22/25

The key battle on the Big 12 schedule Saturday features the BYU Cougars at the Cincinnati Bearcats. These teams have eyes on the Big 12 championship game, but that road goes through this specific matchup for both of them. BYU has only a single loss, and that was to Texas Tech. Cincinnati has 2 conference losses, first to Utah and then last week to Arizona. The Bearcats have to win, and they would still need help; BYU controls their own destiny at this point. Both the numbers and the eye test say that BYU is the better football team, and that is how I am going to play this one. Give me BYU -2.5.

The Bearcat schedule was soft for the first half of the year, but they have been exposed the last 2 weeks. First, Utah absolutely bullied them and pushed them around on both sides of the ball, controlling the line of scrimmage. Last week, Arizona surprised them with the better offensive attack. I think the hot start for Cincinnati has caused us to think too highly of the Bearcats at this point. BYU is a bully team. The Cougars are big, strong, and prefer to push people around. They are most similar to Utah, who clobbered the Bearcats, and the only team they haven’t been able to bully this season is the Red Raiders. I expect BYU to impose its will and play their style, and they should hand Cincinnati its third straight loss.

BYU vs Cincinnati Prediction: BYU Cougars -2.5 (-110) available at the time of publishing. Playable at that number.

If you’re looking for a new sportsbook, check out Bet365, the world’s #1 sportsbook. They have an amazing sign-up offer where you can INSTANTLY receive $200 in bonus bets from a $5 wager, regardless of whether that bet wins or loses! There’s no catch, it’s really that simple. Join Bet365 right now ⏰ in time to fade or follow our experts’ BYU vs Cincinnati predictions.