California Golden Bears vs Stanford Cardinal Prediction, Odds and Picks for Today, 11/22/25

The California Golden Bears will travel to take on the Stanford Cardinal in an ACC matchup this Saturday night. California has a record of 6-4 and it is 3-3 in conference games. The Golden Bears are coming off a big 29-26 overtime win against Louisville in their last game. Quarterback Jaron-Keawe Sagapolutele had arguably his best game in his young collegiate career, throwing for 323 yards and 2 touchdowns against an excellent defense. Sagapolutele is a true freshman but showed his potential, especially on his game-winning throw in overtime on 4th-and-goal. Stanford has a record of 3-7 and a conference mark of 2-5. The Cardinal are currently on a 3-game losing streak, including a 20-15 loss in their last game against North Carolina. Freshman quarterback Elijah Brown threw for 284 yards, 1 touchdown and 1 interception in the loss. Both teams are coming off a bye this last weekend, so they should be ready to go.

This is the “Band is on the Field” rivalry, so each team certainly has this game circled. California has won the last 4 meetings between these 2 teams, including 2 double-digit wins at Stanford. In a battle of what will be freshman quarterbacks, I’m leaning towards Sagapolutele and California in this game. As a freshman, Sagapolutele is currently eighth in college football in passing attempts with 364 attempts. He has completed more than 60% of those throws and has accumulated 2518 yards passing. That all goes to show that California loves to throw the football, and head coach Justin Wilcox trusts his freshman to air it out. I think the Golden Bears have a good opportunity to test a struggling Cardinal secondary Saturday night. Stanford currently ranks 134th in passing yards allowed per game at a total of 284.5 yards. Elijah Brown will likely be making his second start of his career with more left to prove, while Sagapolutele has shown his development toward consistency as the season has progressed. Give me California to build off a big win against Louisville.

Cal vs Stanford prediction: Cal -3 (-105) available at time of publishing. Playable at that number.

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