East Carolina Pirates vs Tulane Green Wave Prediction, Odds and Picks for Tomorrow, 10/09/25

Following a mutual Week 6 bye, the East Carolina Pirates travel to New Orleans to take on the Tulane Green Wave. Both of these teams are tied at 1-0 in the American Athletic Conference, but Tulane’s overall record is 1 game better than East Carolina’s 3-2 mark. Oddly enough, it is ECU that is 4-1 when you consider the ATS metrics, while Tulane is 3-2.

By the numbers, Tulane has played a harder strength of schedule than ECU by nearly 50 spots in ESPN and Sagarin’s rankings, but I don’t see it that way. Duke and Northwestern aren’t much better than NC State, if at all, while Coastal and Army are in a similar tier as South Alabama and Tulsa. The biggest difference is ECU’s win over FCS Campbell, as Tulane hasn’t played an FCS opponent. It all ultimately evens out, as both teams were decisively defeated by the best opponents on their schedule to this point when ECU lost at home to BYU and Tulane lost at Ole Miss. For what it’s worth, the BYU-ECU game felt closer than the score indicates, while it never felt like Tulane had a chance against Ole Miss. Not really an apples-to-apples comparison, but interesting to note considering BYU is better than Ole Miss in multiple advanced defensive metrics like yards per play, PPA per play, havoc generated, and standard down PPA.

My power ratings suggest that Tulane should be giving closer to a field goal in this game rather than a touchdown, which stands out even more to me when considering the Pirates are 6-1 ATS as conference road dogs of at least 4 points since the start of the 2021 season – Blake Harrell’s first full season as ECU’s defensive coordinator. Now the head coach, Harrell’s squad is top 50 nationally in every advanced defensive metric I evaluate weekly, including 11th in havoc generated, 16th in points allowed per quality drive, 36th in opposing PPA per play and 37th in standard downs PPA. Look for ECU’s defense to be the primary catalyst in the Pirates keeping this game close on the road. If QB Katin Houser is able to limit turnovers, the Pirates may even have a chance to win this one outright. Give me the points with ECU.

East Carolina vs Tulane prediction: East Carolina Pirates +7 (-115) at the time of publishing. Playable to +6. 

Check out Bet365, the world’s #1 sportsbook. They have an amazing sign-up offer where you can INSTANTLY receive $200 in bonus bets from a $5 wager, regardless of whether that bet wins or loses! There’s no catch, it’s really that simple. Join Bet365 right now ⏰ in time to fade or follow our experts’ East Carolina vs Tulane predictions.