Indiana Hoosiers vs Maryland Terrapins Prediction, Odds and Picks for Saturday, 11/01/25

The Indiana Hoosiers head to College Park to take on the Maryland Terrapins on Saturday afternoon. The undefeated Hoosiers have now climbed all the way to #2 in the nation, and with Penn St falling apart, there seems to be nothing that would stand in their way of running the table. Don’t get me wrong, Maryland is a respectable football team; but they should get bulldozed on Saturday. I don’t know where you stand, but I am done doubting the Hoosiers, and I am pretty much on board for them to win by whatever margin you want to give me. I’ll take Indiana -22.

The Hoosiers were the Cinderella story of college football last year, and this team is even better. Curt Cignetti has attracted more talent to the program, and this group is bigger, stronger, and deeper, and Cignetti still has that Rodney Dangerfield attitude about him nonetheless. This is one of my favorite teams in the country against the number, because you know they won’t stop trying to score just because the game gets lopsided. It is like they have to prove something every possession. Maryland is a fun team, and they have an exciting young QB with a talented arm, but they are going to be overwhelmed in this spot. I’ll take the Hoosiers to roll on the road.

Indiana vs Maryland Prediction: Indiana -22 (-110) available at the time of publishing. Playable to -23.5.