Kansas State Wildcats vs Utah Utes Prediction, Odds and Picks for Saturday, 11/22/25

The Utah Utes are rolling right now with their sights set on a potential trip to the Big 12 title game, while Kansas State is fighting for their bowl game eligibility sitting at 5-5 overall. Regardless of each squad’s motivation factor entering this matchup, this is quite a hefty point spread sitting at -17.5 in Utah’s favor at the time of writing. While the Utes have won their last three by an average margin of 34.6 points per game, they’ve also faced off against what are likely the three worst defenses in the Big 12.

The Wildcats’ defensive unit isn’t world beaters, but they’ve made some big plays throughout the 2025 campaign and rank a respectable 54th in net points per drive and 47th in defensive success rate. Offensively, the Wildcats have posted at least 34 points in half of their games this season and are slightly above average ranking 60th in net points per drive. With all things considered, I’ll take Kansas State to cover on the road.

Kansas State vs Utah prediction: Kansas State +17.5 (-110) available at time of publishing. Playable at that number or better.