Miami Hurricanes vs SMU Mustangs Prediction, Odds and Picks for Today, 11/01/25

The Miami Hurricanes have proven they’re far from bulletproof. After tossing 4 interceptions in a costly loss to Louisville — a defeat that came as 13-point home favorites — the Canes now face another tricky matchup against a sneaky SMU squad. On paper, this looks like another opportunity to clobber for Miami, after all they scored 42 unanswered against Stanford last week. However, bettors should beware: the Mustangs are far more dangerous than their recent loss to Wake Forest suggests.

SMU may have fallen off the national radar, but this is still a team with firepower and pride. They rolled through much of last season and are eager to prove that their success wasn’t a 1-year wonder. With the game in Dallas, the atmosphere will be electric, and SMU will be amped to showcase its talent on a bigger stage.

Miami’s offense remains explosive, but turnovers and inconsistency have been recurring issues for QB Carson Beck. Laying nearly 2 touchdowns against a motivated, well-coached team like SMU feels like too tall an order. The Hurricanes could very well win, but the spread gives plenty of room for the Mustangs to cover — and possibly more.

SMU on the money line might tempt the bold, but the smart play here is to grab the points and ride with the Ponies.

Miami vs. SMU prediction: SMU Mustangs +12.5 (-110) available at  time of publishing. Playable to +12.

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