Michigan Wolverines vs Maryland Terrapins Prediction, Odds and Picks for Saturday, 11/22/25

The Maryland Terrapins have lost six straight entering Saturday’s home contest against a top-20 Michigan Wolverines squad. While all hope might seem lost, the Terrapins have their backs against the wall if they hope to make a bowl game this season. Half of Maryland’s losses have come in one-possession games as the defense isn’t all too bad — ranking 43rd in net points per drive allowed — but their recent schedule has seen some high-powered offensive units like Indiana and Illinois. Michigan ranks 91st in plays per second this season and has a top-20 rushing play percentage in FBS, meaning the Wolverines lean on methodical drives while feeding the run game. In other words, the offense isn’t built to pull away via explosive plays.

Michigan has failed to cover as double-digit favorites in three straight games, escaping with narrow wins over the last two weeks over Purdue and Northwestern. The recent struggles are largely due to some turnover issues from QB Bryce Underwood which could continue in this matchup as the Terrapins have the 12th-best turnover margin in FBS. With all things considered, I’ll take Maryland to cover at home.

Michigan vs Maryland prediction: Maryland +13.5 (-110) available at time of publishing. Playable at that number or better.