New Mexico Lobos vs UNLV Rebels Prediction, Odds and Picks for Today, 11/01/25

The UNLV Rebels are 0-2 against the spread as home favorites this season, welcoming in a New Mexico Lobos squad that has put together some entertaining results in 2025. The Lobos offense has proven to be a capable unit, ranking 24th in quality drive rate and 36th in points per quality drive. On the contrary, the UNLV defense has struggled to stall drives and ranks 123rd in points per quality drive allowed.

The Rebels have primarily struggled against the run, ranking 113th in EPA/rush defensively – which likely won’t bode well against a New Mexico team that likes to run the football. Offensively, we know the UNLV offense is capable of lighting up the scoreboard, ranking 17th in points per game (37.1), but the defense is incredibly unreliable and the Lobos are certainly capable of keeping this one close. I’ll take the Lobos to cover on the road.

New Mexico vs UNLV prediction: New Mexico Lobos +4 (-110) available at time of publishing. Playable down to +3.5 (-110).

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