Notre Dame Fighting Irish

Notre Dame Fighting Irish vs Pittsburgh Panthers Prediction, Odds and Picks for Today, 11/15/25

Acrisure StadiumABC
Notre Dame
7-2
Notre Dame
Today
Pittsburgh
7-2
Pittsburgh
Pittsburgh Panthers
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Notre Dame vs Pittsburgh Pickswise Expert Predictions

Point Spread Pick
Notre Dame -11.5(-110)

This is less about backing Notre Dame and more about fading Pittsburgh. The Panthers have been one of the hottest teams in the country, winning 5 straight and covering all 5 in the process. That streak has vaulted them into the Top 25 and put them squarely in the College Football Playoff discussion. The talking heads are all saying the same thing — that the road to the ACC and possibly the playoff runs through Pittsburgh.

The logic is easy to buy into. Pitt faces Notre Dame this week, Georgia Tech next week, and then closes the season against Miami. If the Panthers run the table and win the ACC, they’re in the playoff. The market is leaning into that narrative, but the number tells a different story. Despite the hype, despite both teams being ranked, Notre Dame is still laying double-digits. That’s not a mistake — it’s a message. The Fighting Irish just demolished Navy 49-10, but the market still refuses to believe they can dominate a ranked opponent like Pittsburgh. The oddsmakers disagree. When a ranked team catching points looks “too good to be true,” it usually is. The Panthers have become a public underdog, and that’s not a role we’re eager to buy into. The side says Notre Dame.

Game Totals Pick
Under 55.5(-115)
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Napier Montgomery

College football handicapper for Pickswise, specializing in college football, soccer and college basketball. Much prefer betting on the smaller/forgotten games than the big matchups, where the lines are a lot more vulnerable. PhD in Victorian Literature, putting my skills of the written word to the test with betting analysis.
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