Oklahoma Sooners vs Temple Owls Prediction, Odds and Picks for Today, 09/13/25

The Temple Owls rank top-20 in both total defense and total offense through two weeks of football and host the Oklahoma Sooners for what will serve essentially as the Owls’ Super Bowl this season. I expect Temple to be up for this matchup, but the Owls’ recent success has come against UMass and Howard, quite the stark contrast in competition level when matching up with Oklahoma, who has already battled a tough Michigan squad. While I don’t expect Temple to necessarily light things up, scoring multiple touchdowns is certainly a feasible task as the Sooners’ front seven has been a slight weak spot. The rushing defense surrendered 146 yards on the ground against Michigan, and allowed FCS Illinois State to rush for 4.5 yards per carry. Furthermore, the Sooners D has generated only 3 sacks through 2 games.

The Temple offense has moved the ball well, ranking 15th in 20+ yard plays across FBS in 2025. I expect the Owls to put up some points, but the Sooners offense should run rampant on this Temple defense yet to face a Power 5 opponent. QB John Mateer appears to be a legitimate Heisman contender and the pure talent in skill positions surrounding him will be a tall task for Temple. With all things considered, I’m backing both offenses in this spot and will take the over.

Oklahoma vs Temple prediction: Over 51.5 (-110) available at time of publishing. Playable at that number or better.

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