Oregon State Beavers vs Oregon Ducks Prediction, Odds and Picks for Today, 09/20/25

The Oregon State Beavers are off to an 0-3 start, limping into a rivalry matchup against the college football giants – the Oregon Ducks. The rivalry is officially dubbed “The Civil War,” though I don’t expect this to be much of a battle, let alone a war. The Beavers have struggled with turnovers, and their defense is giving up 38.3 points per game. While crazy things have happened historically in rivalry matchups, the underlying numbers suggest Oregon can certainly run away with this one.

Oregon State ranks outside of the top 100 in a variety of statistical categories including EPA margin, defensive success rate, and net field position. Furthermore, the Beavers rank 132nd in EPA/rush on both offense and defense, along with the 115th-best mark in EPA/dropback. Oregon, on the other hand, ranks top-25 in each of the aforementioned categories. The gap of talent is clear, and the Ducks’ defense should give Oregon State QB Maalik Murphy fits, ranking 4th in defensive havoc. I struggle to see any route for Oregon State to keep up with the Ducks; I’ll take Oregon to cover at home.

Oregon State vs Oregon prediction: Oregon -35 (-110) available at time of publishing. Playable at that number or better.

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