Penn State Nittany Lions vs Clemson Tigers Prediction, Odds and Picks for Today, 12/27/25

The Penn State Nittany Lions and the Clemson Tigers at Yankee Stadium? While it may seem like something out of a movie, it’s just the Pinstripe Bowl. In the beginning of the regular season, if you told us these two would be squaring off in the postseason, we would have thought it would have been in the College Football Playoff. Instead, two of the most storied programs in college football meet in the Bronx before New Year’s Day. The question going in is which team can handle that better? The signs point to the Tigers.

We can point out this number opened with Clemson spotting a field goal plus the hook to PSU. That type of price typically lends to a favorite number because it makes the field goal plus the half point attractive to take with the underdog. So far, the market has bitten down, and the line has moved to a field goal accordingly. However, that’s not the only reason why we like the Tigers here. Let’s talk about coaching: Terry Smith vs. Dabo Swinney. Who are you taking? Dabo, of course. Swinney will find a way to craft a narrative to get his team fired up for this opportunity even if its season went off the rails. Penn State may have a lot more local support in New York, but none of that actually matters against a team like Clemson, who is built for stages even like this one. Tigers roll.

Penn State vs Clemson prediction: Clemson Tigers -3 (-110) available at time of publishing. Playable at the number.

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