Texas Tech Red Raiders vs Arizona State Sun Devils Prediction, Odds and Picks for Today, 10/18/25

One of the biggest games of the season in the Big 12 takes place in the desert this week, as the Texas Tech Red Raiders face the Arizona State Sun Devils. Texas Tech comes into the contest at 6-0 and rapidly climbing the national rankings as voters realize this team is not a pretender. The defending conference champ Sun Devils, though, find themselves in an early must-win spot; if they take a 2nd conference loss, it will be hard to climb back into that conference title game from there. The biggest issue in this game is injuries, especially when it comes to the starting QBs, and that makes this game especially hard to handicap. I am, for now, taking the Red Raiders at -7.5.

It looks like Sam Leavitt will suit up for the Sun Devils after missing last week’s game against Utah. ASU was whooped soundly in his absence. Even with Leavitt though, this is not last year’s Sun Devil team. The previous 2 games saw ASU narrowly survive against TCU and Baylor, and Texas Tech is far better than either of those squads. To me, too much of this offense is just about forcing the ball to star WR Jordyn Tyson, and defenses are catching on to it. On the other side, Behren Morton is listed as questionable, but my sense is he is on the doubtful side. The Raiders are better equipped to play with a backup QB than is ASU though, so they should be okay. Arizona State is a strong rush defense, but their passing defense is much more vulnerable, and they have some injuries in the secondary on top of that. This is a spot where Texas Tech can show that they have talent and depth across the board, and I think they win; winning by more than a touchdown is a tougher bet, but I’ll go with it. Tons of early money is flooding the ASU side too, and I generally prefer to avoid that.

Texas Tech vs Arizona State Prediction: Texas Tech -7.5 (-110) available at the time of publishing. Playable at that number.

You can bet on our Texas Tech vs Arizona State pick at DraftKings Sportsbook, which has thousands of betting options available and a great new customer offer where you can get $200 in bonus bets instantly AND $200 off NFL Sunday Ticket! Click here 👈🏼 to sign up for a DraftKings account now.