Tulsa Golden Hurricane vs East Carolina Pirates Prediction, Odds and Picks for Today, 10/16/25

The Tulsa Golden Hurricane and East Carolina Pirates clash in what oddsmakers have projected to be a lopsided affair in favor of the hosts. Ever since upsetting Oklahoma State as 10-point underdogs, Tulsa has failed to cover the spread as multi-score underdogs in back-to-back games. It’s been a mess for the Golden Hurricane; Tulsa ranks 118th in EPA/dropback, 124th in EPA/rush and 110th in points per quality drive. It’s been a struggle to move the football, and I don’t expect that to change against a solid East Carolina defense.

The Pirates rank 16th in defensive success rate and 42nd in total yards per game allowed. ECU has primarily excelled at stalling drives, ranking 27th in turnovers gained, 5th in red zone defense and 25th in 3rd/4th down success rate defensively. While the defense hasn’t been much better, East Carolina is averaging just 23 points per game against FBS opponents and hasn’t exactly lit up the scoreboard. I expect East Carolina to build an early lead, lean on the run game and chew this one out. I’ll take the under.

Tulsa vs East Carolina prediction: Under 54.5 (-110) available at time of publishing. Playable at that number or better.

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