Utah Utes vs Kansas Jayhawks Prediction, Odds and Picks for Friday, 11/28/25

The final week of the regular season gets going for the Big 12 on Friday afternoon as the Utah Utes take on the Kansas Jayhawks. Both teams have lots at stake here. For Kansas, a win would mean bowl eligibility. For the Utes, there is still an outside chance at both the Big 12 Championship game (if BYU somehow loses to UCF), or the playoffs (if lots of things go wrong for multiple other teams). The fact that Utah plays first but does not control its own destiny means that they need to win, and win impressively. This is a lot of points on the road, but I am taking Utah -12.5 on Friday.

It is going to be a cold afternoon in Lawrence when this game kicks off, and that is likely to favor the running games and the defenses. Both run defenses are poor, ranking outside the top 100 in yards allowed per game, but the eye test says the Utah defense is much more likely to stiffen up in this spot. The Utah offense should have no trouble shredding the Kansas defense, as pretty much every opponent has all season. Aside from a win against Oklahoma State sandwiched in the middle, Kansas has lost 4 of its last 5 games, and they have been pushed around badly in most of those. Utah should be able to bully Kansas in the trenches, and I suspect if we get late in the game and Kansas realizes they can’t win, but Utah is still trying to hang points to arbitrarily enhance their postseason chances, we might see Utah pull away late.

Utah vs Kansas Prediction: Utah -12.5 (-110) available at the time of publishing. Playable at that number.