West Virginia Mountaineers vs Arizona State Sun Devils Prediction, Odds and Picks for Saturday, 11/15/25

The West Virginia Mountaineers will travel this Saturday to take on the Arizona State Sun Devils in a Big 12 matchup. West Virginia has a record of 4-6 and a conference record of 2-5. They have won two straight games, including a 29-22 win over Colorado last weekend. The Mountaineers won the game behind freshman quarterback Scotty Fox Jr. Fox threw for 202 and 1 touchdown. West Virginia has now won two out of the three starts by Fox. Fox also led a win against Houston, and his one loss was 23-17 against TCU. Arizona State has a record of 6-3 and a conference record of 4-2. The Sun Devils are coming off a 24-19 win against the Iowa State Cyclones. Quarterback Sam Leavitt missed the game with injury, but Jeff Sims stepped in and threw for 177 yards and 1 touchdown. Sims won the game mostly with his legs, running for 228 yards and 2 touchdowns. The mark set a quarterback rushing record for Arizona State’s school history. The Sun Devils will need another good performance from Sims with Leavitt out for the remainder of the season. 

This will be an intriguing matchup of quarterbacks that did not start the season under center for these schools, but have both taken control of the offense in exciting fashion. Fox is much younger and more inexperienced than Sims. Fox is a true freshman while Sims is in his sixth season of college football. There should be a good amount of ground game in this matchup. In their two wins over Houston and Colorado, West Virginia ran the football efficiently and consistently. Head coach Rich Rodriguez has always favored the running game. West Virginia currently runs the football 57% of the time and they rank 27th in the FBS with 4.5 yards per carry. Arizona State will need to rely on Sims legs again with receiver Jordyn Tyson out with an injury. This game will come down to whoever can tackle better on defense. Sims should be able to find success against a defense that has struggled in the past against dual-threat quarterbacks. Earlier this season, West Virginia gave up 38 points to BYU in a loss, and 48 in a loss to Utah. Both of those teams run a high number of designed quarterback runs and found a lot of success against West Virginia. I expect Arizona State to find similar success.

Arizona State -11.5 is available at the time of publishing. Playable at that number.