Wisconsin Badgers vs Alabama Crimson Tide Prediction, Odds and Picks for Today, 09/13/25

The Wisconsin Badgers and Alabama Crimson Tide face off for the second meeting of the home-and-home series after a dominant Alabama win in 2024. Last time out, the matchup went just about as expected. However, both Wisconsin and Alabama have looked like two completely different teams in their respective season-opening games, and we don’t really know which version of either squad will show up for this one. The only unit that has been consistent on their side is the Badgers’ defense. Wisconsin ranks 3rd in total defense and 7th in sacks per game (4.0). Furthermore, the Badgers rank 2nd in fewest penalties and 10th in overall time of possession meaning the Crimson Tide are unlikely to catch many breaks and will have to rely on big plays if Wisconsin’s offense finds success.

Stylistically, the way the Badgers play football, in theory, should make it difficult for Alabama to pull away. As we saw in Week 1 against Florida State, a few poor decisions can snowball into disaster for this Crimson Tide squad. I expect Wisconsin to lean on the run game, as QB Billy Edwards Jr.’s status is still up in the air at the time of writing, and the run game is what crushed Bama against the Seminoles. I expect this to be a slow-paced dog fight, and I’ve got the Badgers looking to make a statement keeping this thing within 3 touchdowns.

Wisconsin vs Alabama prediction: Wisconsin +20.5 (-110) available at time of publishing. Playable at that number or better.

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The Alabama Crimson Tide offense looked like a well-oiled machine in a 73-0 win in Week 2, though it was against a far inferior ULM opponent. This time around, Bama faces the best defensive unit it’s seen to date as the Wisconsin Badgers rank top-3 in total defense, 7th in sacks per game (4.0) and 4th in rushing defense. Alabama really struggled moving the ball in the run game against Florida State, and I expect that to be the case against the Badgers’ elite front seven. This is a Wisconsin team that has done a fantastic job of limiting mistakes, ranking 2nd in fewest penalties while also ranking 10th in overall time of possession. Combine that with the Crimson Tide’s relatively troublesome run game, and Bama will likely have to rely on big plays through the air against one of the best secondary units in the Big Ten.

While I expect the Wisconsin defense to present some issues for the Bama offense, the Badgers offense isn’t exactly reliable in this matchup. QB Billy Edwards Jr’s status is still up in the air at the time of writing, and although the run game has been efficient, going up against the Alabama front seven is a much taller task than facing Miami (OH) or MTSU. Despite dominating time of possession through two games, Wisconsin ranks 127th in FBS in plays per second. The tale of the tape calls for this game to be an incredibly slow-paced dog fight, and I’ll take the under.

Wisconsin vs Alabama prediction: Under 46.5 (-110) available at time of publishing. Playable at that number or better.