MLS Best Bets for July 22: Top Picks, Predictions & Odds for Wednesday's Matches
MLS is back! The World Cup is officially over after Spain beat Argentina in last Sunday's World Cup Final, and while we had an appetizer of games last Thursday and Friday, the MLS fully returns from its summer break with a full 15-game slate on Wednesday, July 22. We have tons of hot matchups, including an FS1 doubleheader with Charlotte FC vs Atlanta United at 8:15 pm ET and LAFC vs Real Salt Lake at 10:30 pm ET. In addition to those games, we also have Inter Miami vs Chicago Fire, Columbus Crew vs NYCFC, Philadelphia Union vs New York Red Bulls and Nashville SC vs CF Montreal. You can find out our expert MLS picks for all 15 games on Wednesday night, but for now, let's break down our 3 MLS best bets.
MLS best bet today: Charlotte FC ML over Atlanta United (-105)
Odds available at Caesars Sportsbook at time of publishing. Playable to -130.
Atlanta United have lost 5 of their 7 away MLS matches this season. The Five Stripes have scored only 3 goals on their travels, and another defeat should await them against a solid Charlotte FC team that won both of its last 2 games before the break for the World Cup.
Get stats, trends and more for our expert's 5-star Charlotte FC vs Atlanta United best bet
MLS best bet: Nashville SC ML over CF Montreal (-200)
Odds generally available at time of publishing. Playable to -220.
Nashville SC are setting a fast pace at the top of the Eastern Conference and can make it 5 wins from 5 by easing to a home win over struggling CF Montreal. BJ Callaghan's team can register a victory and a clean sheet against their Canadian visitors, who have lost 6 of 8 MLS road matches.
Read the full analysis of our Nashville SC vs CF Montreal best bet
MLS best bet: San Jose Earthquakes ML over Orlando City SC (-180)
Odds available at Caesars Sportsbook at time of publishing. Playable to -215.
San Jose Earthquakes have won 10 of their 15 MLS matches this season. They signed off for the break with a 3-1 hammering of the Portland Timbers in Oregon, and the Earthquakes can return to action with a home win over Orlando City SC.
Don't miss our full San Jose Earthquakes vs Orlando City prediction for Wednesday's MLS matchup
MLS predictions for Wednesday, July 22
Want even more MLS predictions? Check out our expert picks for all 15 games on Wednesday below!
- Inter Miami vs Chicago Fire prediction
- FC Cincinnati vs Vancouver Whitecaps prediction
- New England Revolution vs Toronto FC prediction
- Columbus Crew vs New York City FC prediction
- Philadelphia Union vs New York Red Bulls prediction
- Charlotte FC vs Atlanta United prediction
- Houston Dynamo vs DC United prediction
- Nashville SC vs CF Montreal prediction
- Sporting Kansas City vs Minnesota United prediction
- Colorado Rapids vs San Diego FC prediction
- Austin FC vs Seattle Sounders prediction
- LAFC vs Real Salt Lake prediction
- San Jose Earthquakes vs Orlando City prediction
- LA Galaxy vs St. Louis City prediction
- Portland Timbers vs FC Dallas prediction
