2022 NFL schedule release: Breaking down every primetime game

Los Angeles Chargers quarterback Justin Herbert (10) throws a pass against the Kansas City Chiefs in the second half at SoFi Stadium.
Photo of Andrew Ortenberg

Andrew Ortenberg


Show Bio

I'm an NFL handicapper here at Pickswise who was raised in a household full of sports fanatics. Since I unfortunately never had LeBron James' jumping ability I wasn't able to make it to the NBA, and chose writing about sports as the next best thing. An avid sports bettor myself, I'm excited to get to write about the industry as it gets set to take off across the country. Buckle up. For Andrew Ortenberg media enquiries, please email contact@pickswise.com.
Read more about Andrew Ortenberg

The 2022 NFL schedule is out, and we’re inching closer to the start of training camps. We now know when all the marquee matchups will be during the regular season, and there’s a lot to look forward to. With schedules out oddsmakers are starting to post numbers, and I recently took a look at the opening betting lines for every Week 1 game.

Today we’ll be breaking down all the primetime games in 2022. The NFL understandably saves its best games for the standalone slots that get the most eyeballs, and there are a ton of great primetime matchups this year. Let’s dive in, and we’ll group them by day of the week:

Thursday Night Football

Week 1 – Bills (-1) at Rams (NBC)

Week 2 – Chargers at Chiefs (Amazon)

Week 3 – Steelers at Browns (Amazon)

Week 4 – Dolphins at Bengals (Amazon)

Week 5 – Colts at Broncos (Amazon)

Week 6 – Commanders at Bears (Amazon)

Week 7 – Saints at Cardinals (Amazon)

Week 8 – Ravens at Buccaneers (Amazon)

Week 9 – Eagles at Texans (Amazon)

Week 10 – Falcons at Panthers (Amazon)

Week 11 – Titans at Packers (Amazon)

Week 12 – Patriots at Vikings (Thanksgiving, NBC)

Week 13 – Bills at Patriots (Amazon)

Week 14 – Raiders at Rams (Amazon)

Week 15 – 49ers at Seahawks (Amazon)

Week 16 – Jaguars at Jets (Amazon)

Week 17 – Cowboys at Titans (Amazon)

TNF recap: There are some great Thursday Night Football games this year. TNF is often where the lesser primetime games get placed and where lower-profile teams get a chance to shine, but there are still some highlights. The season-opening showdown between the Bills and Rams is going to be a good one.

No disrespect to Commanders/Bears, Falcons/Panthers or Jaguars/Jets, but those are going to be some of the least anticipated primetime matchups of the season. Chargers/Chiefs is another highlight, but personally I’m most looking forward to Ravens/Buccaneers in Week 8. I can’t wait to see Lamar Jackson and Tom Brady go at it again.

Sunday Night Football

Week 1 – Buccaneers at Cowboys (NBC)

Week 2 – Bears at Packers (NBC)

Week 3 – 49ers at Broncos (NBC)

Week 4 – Chiefs at Buccaneers (NBC)

Week 5 – Bengals at Ravens (NBC)

Week 6- Cowboys at Eagles (NBC)

Week 7 – Steelers at Dolphins (NBC)

Week 8 – Packers at Bills (NBC)

Week 9 – Titans at Chiefs (NBC)

Week 10 – Chargers at 49ers (NBC)

Week 11 – Bengals at Steelers (NBC)

Week 12 – Patriots at Vikings (NBC)

Week 13 – Colts at Cowboys (NBC)

Week 14 – Chiefs at Broncos (NBC)

Week 15 – Patriots at Raiders (NBC)

Week 16 – Buccaneers at Cardinals (NBC)

Week 17 – Rams at Chargers (NBC)

SNF recap: What a slate of games for NBC. Al Michaels left for Amazon this offseason, so it’ll be Mike Tirico calling games opposite Cris Collinsworth for Sunday Night Football. They’ll start off with a bang with Cowboys/Bucs, which is a rematch from Week 1 last year. Steelers/Dolphins is really the only matchup on this entire SNF schedule that feels a bit underwhelming.

The first handful of weeks are absolutely stacked, and I’m also super excited for Rams/Chargers to have another battle for Los Angeles in Week 17. We’ll only see that once every four years. Speaking of things we only see every 4 years, the Bills will play the Packers, which means we get a rare Josh Allen vs Aaron Rodgers meeting.

Monday Night Football

Week 1 – Broncos at Seahawks (ESPN)

Week 2 – Titans at Bills (ESPN), Vikings at Eagles (NBC)

Week 3 – Cowboys at Giants (ESPN)

Week 4 – Rams at 49ers (ESPN)

Week 5 – Raiders at Chiefs (ESPN)

Week 6 – Broncos at Chargers (ESPN)

Week 7 – Bears at Patriots (ESPN)

Week 8 – Bengals at Browns (ESPN)

Week 9 – Ravens at Saints (ESPN)

Week 10 – Commanders at Eagles (ESPN)

Week 11 – 49ers at Cardinals (ESPN)

Week 12 – Steelers at Colts (ESPN)

Week 13 – Saints at Buccaneers (ESPN)

Week 14 – Patriots at Cardinals (ESPN)

Week 15 – Rams at Packers (ESPN)

Week 16 – Chargers at Colts (ESPN)

Week 17 – Bills at Bengals (ESPN)

MNF recap: If you’re watching primetime NFL games this season, get ready to see a lot of Russell Wilson. The league is understandably pushing his first handful of games with the Broncos hard. He’ll be on MNF in Week 1, and then again in Week 6. They’re also on Thursday Night Football in Week 5.

The first half of the MNF slate isn’t great, but it’s backloaded with a bunch of cool matchups down the stretch. Fortunately, Monday Night Football doubleheaders are back, as we’ll get a double-feature in Week 2 with Titans/Bills and then Vikings/Eagles.

Pickswise is the home of free expert NFL Picks and NFL Odds. Be sure to check out all of our season previews and NFL Futures Bets leading up to the 2022 NFL season.

By signing up you agree to our terms and privacy policy