NFL Odds - Best Odds and NFL betting lines this week

Welcome to the NFL Odds section where we bring the best NFL Odds this week from the Top Online Sportsbooks. You’ll find all things NFL Odds here throughout the season from Weekly NFL Betting odds including Money Line, Against the Spread and Totals, as well as selected NFL futures odds, such as the current NFL Playoff Odds. Be sure to also check out all of our experts’ NFL Best Bets and NFL Picks for this week’s NFL plays.

Looking for Odds on the Super Bowl? Check out the Pickswise Super HUB for all of our Super Bowl Predictions, including our Super Bowl Prop Bets, along with the latest Super Bowl Odds.


NFL Odds – Best Odds and NFL betting lines this week

NFL Odds

Find all of your NFL odds and NFL betting lines for the entire  NFL season. We break down the most popular NFL odds, including Moneyline, Against the Spread, Over/Unders, Live Odds, Prop Bets, and Futures. With shopping the odds increasingly important with the continued expansion of online sports betting, we also detail how to make the most of this week’s NFL odds and betting lines.

New to betting? Fear not, everything you need to know around NFL odds, including how to read NFL odds, how to understand NFL odds, and Vegas odds are right here, provided by the NFL betting experts at Pickswise.  

NFL Odds Moneyline

NFL Moneyline betting is the simplest way to wager on an NFL game. With NFL Moneyline betting you are simply picking which team will win the game outright. With that, the Moneyline odds are simple, you’ll have set odds for either team to win the match, and if the game results in a tie, the bet is a push and your stake is returned.

NFL Moneyline odds will be displayed in the following format. The Moneyline odds favorite will be given a negative number, -250 for example, this shows the amount you must wager to win $100 profit. The Moneyline odds underdog will be the team with a positive number, +350 for example, this indicates the amount you’ll win for a $100 wager.

NFL Against The Spread betting lines

The NFL Against the Spread Betting lines is unquestionably the most popular form of NFL odds amongst NFL bettors and experts. Unique to the sport, the NFL betting lines against the spread are often discussed widely by sports pundits and experts throughout the game week, in the lead up to the matches. NFL Betting lines against the spread are also widely used in the NFL expert picks throughout the season.

So what are the NFL against the spread betting lines? Well, it’s dissimilar to the Moneyline odds in that you’re not picking the outright winner of the match, but instead who will cover the spread as set by the sportsbooks. Similarly to the Moneyline, you’ll have a favorite and an underdog, but instead of these being reflected in the NFL odds, they’ll be reflected in the spread, with the favorite conceding points such as -7, and the underdog receiving points, such as +7.

In similar fashion to the Moneyline Odds, if the match finishes a tie, with the Against the Spread NFL betting line taken into account the result will be a push and your stake returned. For example, If you wager on Green Bay -5 and they win by 5 points, it will be a push, if they win by 6, your ticket will cash.

NFL Odds Over/Under

NFL Odds over/unders is the most popular NFL odds market in which you aren’t betting on one side or the other. Some bettors prefer to not wager on one team, but rather on the match itself, and the NFL Odds over/unders allows you to do just that, as you’re waging on whether the match points total will go over or under the line, as set by the sportsbooks.

The NFL odds in the over/under markets remain pretty much the same, with either side of the line typically around -110, but instead, it is the betting line that will differ from match to match.

There is lots to consider in making a pick in the over/unders markets, with team news, weather, schemes, and form all to be considered for deciding to go over or under the totals betting line.

Lines can vary greatly depending on the teams, the location, the weather, and much more. It is not unusual to see one match’s NFL betting line for the totals to be set at 38 points the same week as another match is set for 52, so each match provides a unique challenge.

NFL Live Odds

NFL Live odds are a great, exciting way of wagering on an NFL game once the event has started. There are many situations where bettors will look at live odds, be it you’ve missed the pre-game markets, you want to hedge a bet if your pre-game selection is doing well, or you’d rather get a feel for the game before getting involved.

NFL live odds are dynamic in-play odds offered in-line with the events as they take place, reacting, and reflecting the on-field action.

Most of the main pre-game NFL odds markets are offered as NFL Live Odds, such as Moneyline, Totals, Spreads and also some selected Prop Bet markets such as Next Touchdown Scorer and Anytime Touchdown Scorer 

NFL Odds Prop Bets

NFL Odds for Prop Bets are typically split into Team Props and Player Props, with NFL Player Prop particularly popular due to their close propensity to Daily Fantasy Sports contests and their focus on individual player matchups. 

Unquestionably the most popular NFL odds in the prop bet markets are on player touchdowns, with odds on the First, Last and Anytime touchdown scorers offered by the majority of online sportsbooks for every NFL game across the season.

Shopping the betting lines is always important when placing your NFL wagers, with an extra point in your favor against the spread sometimes the difference between winning and losing, and it’s no different when shopping the odds, particularly with player prop bets. You can often see a player +500 to score first with another sportsbook offering +700, which is a sizeable difference.

NFL Odds & NFL Betting lines this week

NFL odds and NFL Betting lines this week are set almost right after the previous week’s matches have concluded. Sportsbooks take the most recent performances into consideration when setting the lines, and will look to go live soon after each game week.

Typically you see movement in the odds and lines early, so it can pay to bet early if the line moves in your favor, but you also run the risk of being on the wrong side of the line come gameday.

NFL Futures Odds

NFL Futures Odds allow bettors to place wagers on bets that will conclude further down the line and not on an individual match. These markets include the likes of the Super Bowl odds, Conference Titles, Divisional winners, Playoffs, and Awards. Placing a futures bet is a great way to have a prolonged interest throughout the season, be it a team-based bet such as a conference title, or a player-based bet such as the MVP betting.

NFL Playoff Odds

The 2020 NFL regular season is set to conclude on January 3rd, 2021, and for the first time in NFL history, 7 teams from each conference are set to make the NFL playoffs.

A popular futures wager, for a team to reach the playoffs, is likely to be even more popular this coming season with the additional spots in each conference.

Betting a team to reach the playoffs offers a bit more safety than betting a team to win their division, as Wild Card teams will also see your ticket cash in this market.

NFL Division Odds

Divisional games are some of the most important and competitive games each year, and winning your division is the most important part of regular season football.

With this, comes some great wagering opportunities with the NFL Division odds, particularly in the more competitive divisions.

Heading into the 2020 NFL these are the current NFL Division Odds.


The most talked-about and popular of the NFL awards odds is the NFL MVP odds. It is widely discussed throughout the season, particularly towards the end of the NFL regular season.

The MVP race is typically a wide-open affair to start the season, with luck and injuries playing a big part in the award winner. Lawrence Taylor was the last non-quarterback or running back to win the league MVP award back in 1986 so it often pays to not stray far from these two skill positions, which is usually reflected in the pre-season NFL MVP Odds.

These are the current Top-15 players with the Best NFL MVP Odds.

NFL Rookie of the Year odds

College Football has a huge following across the US, and with it, events such as the NFL Draft are a huge deal in the sporting calendar, watching the next generation of NFL talent realize their dream of making the league.

Following this, there is considerable interest in players making the switch from college to the NFL and wagering the NFL Rookie of the Year odds. There are two Rookie of the Year awards, and thus, two sets of Rookie of the Year odds, one for the Offensive Rookie of the Year and one for the Defensive Rookie of the Year.

NFL Odds FAQ's

When you read NFL odds with the majority of online sportsbooks, the layout will be fairly similar. You will find the game information, such as teams and the kickoff time, as well as the NFL odds for the main three markets, being Moneyline, Spread, and Totals.

Here is an example of what to expect.
The top team is always the road team and the bottom team, the home side.

The point spread shows how many points the favorite, -10  has to win by to cover the spread, and how many points the underdog with the +10 has to stay within to cover.

O 54.5 is betting the total match points will go over the spread, 54.5 so 55 or more points, and the U 54.5 is the opposite, that the under will hit in the match with 54 or fewer total points.

The Moneyline odds favorite will be given a negative number, -500 in the example above, this shows the amount you must wager to win $100 profit, in this case, $500.
The underdog will be the team with a positive number, +375 for example, this indicates the amount you’ll win for a $100 wager, so your $100 wager will return $375 profit. 

Vegas NFL odds work the exact same way as sportsbook odds, as explained above. Historically Vegas odd would be released much earlier than anywhere else, and while that can still be the case, with the changing legislation around online sports betting its definitely less pertinent today.

One thing that is still used with Vegas NFL odds, and discussed in the lead up to game day, is the Vegas NFL odds opening lines. These are the first NFL betting lines released by the Vegas sportsbooks and casinos once the books open for the following week’s NFL games. This is a useful tool in monitoring line movements throughout the week and particularly discussed with regards to the point spreads which can move a few points across the week.

NFL odds of +200 and -200 are indicators of which team is favorite, and which is the underdog, but also how to calculate your returns on that wager, should it win.

The favorite will be listed with the – symbol and the preceding number shows how much you must stake in order to win a profit of $100. In the example of -200, a $200 stake will return $100 profit, $300 total.

The Underdog will be listed with the + symbol, and the preceding number shows how much you will win in profit from a $100 wager. In the example of +200, a $100 wager would see you win $200 profit for a total of $300.

When the NFL Betting lines come out will vary from sportsbook to sportsbook, but the majority will post their lines right after this week’s games, some as early as Sunday evening.

Some matches the following week may remain without betting lines if teams are playing in the Sunday Night Football game or the Monday Night Football game, with the NFL betting lines for those teams’ next games posted after this week’s match has concluded.