College football betting guide: Expert Week 5 CFB picks, predictions, odds & best bets

Ohio State Buckeyes players Ohio State Buckeyes wide receiver Bryson Rodgers (86), wide receiver Brandon Inniss (11) and cornerback Jermaine Mathews Jr. (24) celebrate after beating Notre Dame Fighting Irish 17-14 at Notre Dame Stadium.
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Lead MLB Writer for Pickswise. A Bostonian with a love for stats and baseball. Using knowledge and passion to find the right bet in MLB, NBA, NFL, and more. A lover of bold sports takes and sweat-free plus-odds picks. For Keith Schmelter media enquiries, please email

Welcome to the Pickswise college football Week 5 betting guide. All of our experts and betting analysts have done the research so that you have everything you need to bet better and hopefully beat your bookie this week! This is your one-stop shop for all the information for your NCAAF bets this weekend. 

College football Week 5 picks 

NCAAF Week 5 betting picks and predictions 

College football Week 5 big-game predictions 

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