Four-pick cross-sport parlay for Thursday (+851): MLB, Europa League, College Football and NFL picks

Cincinnati Bengals quarterback Joe Burrow (9) drops back to hand off to running back Joe Mixon (28) in the second quarter of the NFL Week 3 game between the Pittsburgh Steelers and the Cincinnati Bengals at Heinz Field in Pittsburgh on Sunday, Sept. 26, 2021. The Bengals led 14-7 at halftime. Cincinnati Bengals At Pittsburgh Steelers
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Matthew Lowrimore


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Matthew has been with Pickswise for a while now, covering a wide variety of sports. His main passions are college football and UFC, and those are the sports he has covered the most. Matthew uses a variety of methods to handicap games, including stats, trends, injuries, and situational factors. His goal is to consistently give out winners and will put in the research to try and achieve this. For Matt Lowrimore media enquiries, please email
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We have put together a 4-pick cross-sport parlay that will take you right through Thursday night; it includes action from the NFL, Europa League, College Football and MLB.

One pick is taken from each sport and a winning ticket gives us a nice payout with odds at +851 with DraftKings; that’s more than 8/1! Let’s break down each of these plays.

Europa League: West Ham United -1.5 (-175) vs Rapid Vienna, 3pm ET

West Ham somewhat defied expectations to win their first ever Europa League group stage game last time, beating Dinamo Zagreb 2-0 away from home, and back at the London Stadium, they can secure another win against Rapid Vienna. The Austrians had to battle through three qualifying rounds to make the group stage and lost their opener against Genk. They should be vulnerable to West Ham’s superior roster.

Be sure to check out our full game preview for this matchup.

MLB: Tampa Bay Rays vs Houston Astros ML (-160), 7:10pm ET

Houston has not quite clinched the AL West since Seattle just keeps winning to keep it close. The Astros are expected to start Lance McCullers Jr., who has had a very good season for Houston this year and looks to close it on a high note. He led the team in wins and strikeouts and is a great candidate to be on the mound in Houston’s first playoff game. It is natural for the Rays to let up a bit in this spot while Houston still needs another win to lock things up in the AL West. The Astros are at home and have an advantage on the mound, so it is hard to get away from backing the Astros in this matchup. Take Houston.

Be sure to check out our full game preview for this matchup. You can also read the rest of our MLB picks and predictions, as well as our prop betsparlays, and MLB Best Bets.

College Football: Virginia Cavaliers +5.5 (-110) vs Miami Hurricanes, 7:30pm ET

Both teams have experienced some early struggles this season, and both enter with records of 2-2. It is worth noting that Virginia quarterback, Brennan Armstrong, leads the nation with 426.3 passing yards per game. He also has 13 touchdowns to just 3 interceptions. The Canes on the other hand, are surrendering the second-most passing yards per game in the ACC (245.8).

These teams are used to playing close games against one another. The last 3 meetings have been decided by just 15 total points. Miami is just 1-6 ATS in their last 7 home games going back to last season. In addition, Virginia is 6-2 ATS in their last 8 meetings with Miami. Take the points with Virginia.

Be sure to check out our full game preview for this matchup.

NFL: Jacksonville Jaguars vs Cincinnati Bengals -7.5 (-105), 8:20pm ET

Cincinnati has got off to a solid start with eye-catching wins over the Vikings and Steelers, thanks largely to the rapport of reunited LSU alumni Joe Burrow and Ja’Marr Chase. Rookie receiver Chase has already hooked up with his quarterback to score 4 touchdowns in 3 games, and they are expected to flourish under the lights. As a whole, the Bengals offense is averaging 8.5 passing yards per attempt (tied for 8th-best in the league), and get the chance to feast on a Jaguars defense that has allowed the 3rd-most passing yards per attempt.

What really makes laying more than a touchdown appealing is how stagnant Jacksonville has been on offense. Things have been disastrous for rookie quarterback Trevor Lawrence so fa. He has already thrown 7 interceptions including a pick-6 last week against the Cardinals. Expect Jacksonville to struggle to keep up with Cincinnati’s scoring power, and for the Bengals to pull away.

Be sure to check out our full game preview for this matchup.

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