Premier League Predictions: EPL Picks & Best Bets for This Weekend - Arsenal look to hold their nerve against Newcastle

Arsenal's Kai Havertz celebrating with team-mates. When the final reckoning comes, Arsenal will have high hopes of finishing on top.
Soccer handicapper for Pickswise.
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Manchester City returned to the top of the Premier League for the first time since the opening week of the season with Wednesday’s 1-0 win over Burnley, overtaking long-time leaders Arsenal. The Gunners will have a chance to reclaim top spot when they host struggling Newcastle this weekend, while the Citizens are in FA Cup semi-final action against Southampton.

As the end of the EPL calendar draws closer, the stakes are raised even higher. As such, I’ve picked out my EPL best bets for this weekend’s action. You can also check out our expert soccer picks for all the big EPL matchups throughout the season. 

EPL best bet: Everton ML over West Ham (+195)

Odds courtesy of DraftKings Sportsbook at the time of publishing.

Everton continue their fight for a European spot when manager David Moyes returns to his former club West Ham on Saturday. The Toffees entered the weekend 2 points adrift of 7th place, while relegation-threatened West Ham have a 2-point advantage over Tottenham in 18th. The Hammers have only lost once in their last 5 games, and will be hoping to at least avoid defeat as they battle to beat the drop. 

Everton lost 2-1 at home to Liverpool in the Merseyside derby last weekend, but their away form has been strong . In fact, they have won 4 and lost only 1 of their last 7 road matches, and they look the bet to claim 3 points.

EPL best bet: Tottenham ML over Wolves (-135)

Odds courtesy of DraftKings Sportsbook at the time of publishing.

Tottenham Hotspur are in trouble. They head into the weekend 2 points adrift of safety and are without a Premier League win since December. However, there was certainly room for optimism in last weekend’s 2-2 draw against Brighton, as Roberto De Zerbi’s men played with grit and determination while Xavi Simons produced a moment of brilliance for Spurs’ 2nd goal. A similar effort gives Tottenham a chance against relegated Wolves.

The Championship beckons for Wolves, who have conceded 7 goals in losing their last 2 Premier League matches. Their form has dwindled under Rob Edwards and Spurs can take advantage.

Read our full Wolves vs Tottenham prediction

EPL best bet: Liverpool ML over Crystal Palace and Over 2.5 (-111)

Odds courtesy of FanDuel Sportsbook at the time of publishing.

Liverpool took a huge step towards securing Champions League qualification with last week’s Merseyside derby win and can cement their top-5 status when Crystal Palace head to Anfield. With Alexander Isak returning to fitness and Mohamed Salah back in the goals, it’s worth backing Liverpool to find the net on multiple occasions. The Reds have scored 11 goals in their last 4 domestic home matches.

Palace will have 1 eye on their Europa Conference League semi-final against Shakhtar Donetsk on Thursday and with nothing to play for domestically, manager Oliver Glasner is likely to rotate his squad.

Get our soccer predictions for all the weekend’s big EPL games, plus MLS and the FA Cup semifinals!

EPL best bet: Arsenal ML & Both Teams to Score (+176)

Odds courtesy of DraftKings Sportsbook at the time of publishing.

The pressure is mounting on Arsenal and Mikel Arteta after their significant lead at the top of the Premier League disappeared following Manchester City’s win at Burnley. Expect the atmosphere at the Emirates to be nervy this weekend, with Arsenal in desperate need of a win to quiet the outside noise. 

Fortunately, visitors Newcastle have struggled for form lately, with consecutive defeats against Bournemouth, Crystal Palace and Sunderland seeing them slip to 14th in the Premier League. A home win seems likely and will give Arsenal a big lift heading into the final 4 games of the league season, but the Gunners have kept just 2 clean sheets in 6 league matches, and it would be no surprise if Newcastle manage to find the net in defeat.

Read our full Arsenal vs Newcastle prediction

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