MLB Wednesday parlay at mega +747 odds today 5/22: Dodgers bounce back at home

Los Angeles Dodgers first baseman Freddie Freeman (5) advances to first after a walk in the third inning against the San Diego Padres during game three of the NLDS for the 2022 MLB Playoffs at Petco Park.
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Caleb Wilfinger


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Deputy Editor for Pickswise with years of experience handicapping and giving out winning picks. Lover of all US sports and Southampton FC. For Caleb Wilfinger media enquiries, please email
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The MLB season rolls on today with 13 games on the docket as a number of teams play during the day, while a couple of pivotal series in both leagues wrap up later this evening. Still, with most of the league in action on Wednesday, there is plenty to attack and craft an MLB mega parlay. Let’s dive into today’s MLB parlay picks, with games getting underway with the Mets taking on the Guardians at 1:10 pm ET and concluding with the Dodgers facing off against the Diamondbacks at 10:10 pm ET.

You can also check out all of our MLB picks for today’s action.

Dodgers -1.5 (-148)

Braves -1.5 (+120)

Yankees -1.5 (+130)

MLB parlay odds: +747

For this MLB parlay, I am going with a bet on the Dodgers, Braves and Yankees to all win by multiple runs. Let’s break down each of the 3 legs.

Los Angeles Dodgers -1.5 over Arizona Diamondbacks (-148)

To start off our MLB parlay I’m going with the Los Angeles Dodgers on the run line. Los Angeles stumbled on Tuesday, dropping the middle game of this series 7-3 behind a lackluster offensive performance. However, this is a lopsided looking pitching matchup on paper, one that the Dodgers should take full advantage of. Tyler Glasnow has been brilliant for Los Angeles this season, except for an underwhelming start in his last turn, throwing only 5 innings with 4 runs allowed. However, that’s not all that bad given his sparkling track record this season. We’ve certainly seen worse, and one such example would be any of several of the starts by Ryne Nelson, the Diamondbacks starter on Wednesday. Nelson’s season-long metrics are poor (7.06 ERA) and he recently got shelled by the Tigers to the tune of 8 runs in 5.0 innings. The right-hander could be the perfect tonic for a Dodgers offense that could use a bounce-back effort in this one.

Atlanta Braves -1.5 over Chicago Cubs (+120) 

For the second leg in our MLB parlay I’m going with the Atlanta Braves on the run line. This would have been an outstanding pitching matchup a season ago, but Cubs starter Justin Steele (0-1, 5.46 FIP) has yet to find his groove since returning from the injured list — allowing 11 runs on 12 hits in his past 2 outings. Seeing a struggling starter in Steele could be exactly what a rather disappointing Braves offense needs to regain form in this NL clash. Opposing Steele will be Max Fried (3-2, 3.95 FIP), who is having another typically strong season and who’s elite command against Cubs hitters (1.6 percent walk rate over 62 career plate appearances) bodes well for his chances of posting a quality start. Let’s back the Braves to start strong and win this game by at least 2 runs.

New York Yankees -1.5 over Seattle Mariners (+130) 

To close out this MLB parlay I have the New York Yankees on the run line. While Mariners starter Bryce Miller (3.08 ERA, 0.99 WHIP) has some respectable numbers this season, his underlying metrics (4.23 xERA) suggest he is due for some slight regression, and he has been on a downward trajectory of late — surrendering 10 runs over his last 17.1 innings pitched. Miller will face a daunting task in trying to slow down this Yankees lineup that has yet to lose 3 straight games all season and posts an incredible 121 wRC+ — 2nd in MLB behind only the Dodgers. Furthermore, New York has featured the best offense against right-handed pitching in 2024 (127 wRC+ vs RHP), so Miller could be in some trouble here. On the other side, Nestor Cortes has been terrific in Yankee Stadium, posting a 1.27 ERA and .168 BAA in home starts this season. Let’s get to the window with the Bronx Bombers in this one.

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