MNF NFL Betting Guide: Denver Broncos vs Buffalo Bills picks, predictions, odds & best bets

Russell Wilson and the Denver Broncos meet Josh Allen and the Buffalo Bills in NFL Week 10 Monday Night Football.
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Andrew Wilsher


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Managing Editor of Pickswise. Born and raised in jolly old London, England, with an undying love for the NFL, NBA, soccer and horse racing. A big-time sports bettor who loves futures markets and backing underdogs. Long-suffering New York Jets fan. For Andrew Wilsher media enquiries, please email

NFL Week 10 concludes with Monday Night Football between the Denver Broncos and Buffalo Bills. After a rough start to the season, the Broncos are finally starting to look like the team people expected them to be, especially after beating the Chiefs and holding them to just 9 points last time. Now, they turn their attention to the Bills, who have struggled to meet their lofty expectations thus far as they sit with a 5-4 record. Can Josh Allen and company get things back on track, or will they fall to .500 on the season? Our NFL experts are 84-60-4 on their spread picks this season for +45.4 units, and in this MNF betting guide, we have our best bets, prop picks an even a Same Game Parlay at +1078 odds! Let’s dive in.

NFL MNF Broncos vs Bills Picks 

Broncos vs Bills best player prop bets 

Broncos vs Bills Same Game Parlay 

NFL Week 11 Predictions

With our NFL handicappers on fire this season and up +45.7 units on their NFL picks and up +21.7 units on their NFL best bets, make sure you check out our predictions for every game in Week 11! On top of that, you can also read our NFL Week 11 opening lines analysis, which includes an early bet to make right now!

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