Wise n' Shine: NFL picks and MLB predictions for Thursday, September 15

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Caleb Wilfinger


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Deputy Editor for Pickswise with years of experience handicapping and giving out winning picks. Lover of all US sports and Southampton FC. For Caleb Wilfinger media enquiries, please email contact@pickswise.com.
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Good morning, Pickswise Nation! We’ve got a smaller MLB slate today, but Week 2 of the NFL season is here with an excellent game in the AFC West for Thursday Night Football. Let’s get straight to making your next bet better!

About Last Night

Rock-solid day on MLB totals for Pickswise
The Pickswise MLB team was in-form for Wednesday’s 15-game MLB slate, as our handicappers went 10-4-1 with our over/under total picks. In other baseball news, the Yankees won again while the Mets lost another game to the Cubs. However, the NL East standings didn’t change much, as the Braves lost to the Giants. The Dodgers also lost to the Diamondbacks in a day filled with upsets, but our handicappers were on the right side of that one after picking Arizona to win.

Today’s Slate

Thursday Night Football promises a thriller
Week 2 kicks off in Kansas City, where the Chiefs are 4-point favorites over the Los Angeles Chargers. This could prove to be a pivotal AFC West showdown as both teams are expected to be contending for the division, as well as playoff positioning down the road. Be sure to check out the NFL analysis tab for all of our experts’ thoughts on this game, plus every NFL Week 2 matchup.

Smaller MLB slate today
It’s a smaller MLB slate today, with action getting underway in the afternoon. The White Sox and Guardians get us going at 1:10 pm ET and the Rays and Blue Jays get started on ESPN+ at 3:35 pm ET. Mets vs Pirates is being shown on FOX at 7:20 pm ET, while the A’s battle the Astros at the same time.  Be sure to check out all of today’s MLB predictions.

Best Bet of the Day

NFL: LA Chargers vs Kansas City Chiefs: 1st half under 27
8:15 pm ET, Amazon Prime

While this is a scary proposition considering these two teams and QBs, this total seems a bit inflated. It seemed too high even with Keenan Allen in the lineup, but a 1st half under looks even better with Allen out of the lineup. The Chargers defense is much improved from a season ago and it showed in their victory over the Raiders on Sunday. Los Angeles pressured Derek Carr at a 30% rate, which clearly flustered the Las Vegas quarterback and forced him into mistakes. An under in the 1st half also shields you from late-game fireworks. In 3 games of this Herbert vs Mahomes matchup, each game has gone under in the first half with 17, 24 and 20 total points scored respectively. Make sure you check out our full Chargers vs Chiefs predictions.


You won’t want to miss today’s edition of our daily sports betting show Let’s Bet It! at 10:00 am ET on our YouTube channel at youtube.com/c/Pickswise.

Lauren Jbara and Jared Smith are your hosts today, and they’ll be joined by Pickswise prop analyst Bobby Stanley, also known as “Prop Holiday” to preview the Thursday Night Football matchup. The team will also give their best bets for today’s MLB games, 3 key games on the college football card this Saturday and their Plays of the Day.

You can also access the show through Spotify and Apple Podcasts (search for Let’s Bet It Presented By Pickswise).

You can also check out the latest episode of Pickswise Playbook, our weekly NFL betting show, where Lauren Jbara, Jared Smith and ex-NFL safety Tank Williams break down the entire Week 2 slate and give their best bets.

Best sportsbook promo codes

With the football season getting started, it’s a great time to take advantage of sportsbook offers. Be sure to check out the best sportsbook sign-up bonuses for football.


Thursday Night Football is here and we’ve got plenty of information to make your next bet better. Start with Clevta’s Chargers vs Chiefs picks, then our TNF same game parlay and best prop bets from Bobby “Prop Holliday” Stanley. Be sure to read all about our amazing NFL Week 1 picks after we went 13-3 on spread picks and 4-0 on Best Bets!

With the early games today, you’ll want to get straight on to reading our Thursday MLB mega parlay and today’s YRFI/NRFI best bets.

Diane Knox Balas has the Fortinet Chamionship best bets for this week’s golf and her predictions for this weekend’s LIV Golf event in Chicago are also available.

Be sure to head over to the Analysis tab for even more great sports betting content as it arrives throughout the day.

Stat of the Day

All 3 meetings between Justin Herbert and Patrick Mahomes have gone under the total in the first half.

Pickswise is the home of free sports picks, news, and best bets. Check out our expert NBA picks, MLB picks, NHL picks and Soccer picks for the latest game picks.

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