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Green Bay Packers
Oct 254:25 PMFord Field, Detroit
Detroit Lions
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Green Bay Packers vs Detroit Lions Prediction, Odds and NFL Picks for Sunday, 10/25/26

Parlay
1:00 PM
San Francisco 49ers @ Atlanta FalconsMoneyline - San Francisco 49ers

To start our Sunday NFL parlay, I like the 49ers to remain undefeated when they hit the road to face the Falcons. San Fran is 6-0 and has already proved it can travel, highlighted by its big victory over the Rams in Australia. As for Atlanta, they had a brief renaissance before crashing back down to Earth and is now 2-4. The Falcons are 0-3 at home this season and that winles start should continue.

1:00 PM
Indianapolis Colts @ Minnesota VikingsMoneyline - Minnesota Vikings

Next, I'm backing another undefeated team to win with the Vikings prevailing against the Colts. Indianapolis has been on a torrid run lately, and facing Minnesota off its bye won't make things any easier. The VIkings' defense has once again been tremendous under Brian Flores, and after the Colts struggled against another blitz-heavy team in the Commanders, I expect Minnesota to have the measure of Indy in this one.

4:25 PM
Green Bay Packers @ Detroit LionsMoneyline - Green Bay Packers

I'm rounding off our NFL parlay by taking the Packers as a road underdog against the Lions. Green Bay has won three straight, allowing only 34 total points in that run, and should stymie the Lions and Jared Goff enough to get the victory at Ford Field. Detroit's defense has been a turnstile, allowing nearly 30 points per game, and given Jordan Love's historical success against the Lions (he had six touchdowns and zero interceptions last season), Green Bay looks great value and a strong addition to our parlay.

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