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Los Angeles Rams
Oct 254:25 PMAllegiant Stadium, Las Vegas
Las Vegas Raiders
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Los Angeles Rams vs Las Vegas Raiders Prediction, Odds and NFL Picks for Sunday, 10/25/26

Los Angeles Rams
Las Vegas Raiders
Los Angeles RamsLas Vegas Raiders
NFLSun, Oct 254:25 PM

Both the Los Angeles Rams (2-4) and Las Vegas Raiders (3-3) will be desperate for a win when they square off in Las Vegas on Sunday afternoon. The Rams have dropped two in a row and three of their last four games, while the Raiders are in the midst of a three-game losing streak. Relative to expectations, things are much more dire for Los Angeles. It was favored to win the Super Bowl when this season began; six weeks later, it has to be worried about simply making the playoffs. Head coach Sean McVay’s squad fell to lowly Arizona 18-16 at home last weekend. Puka Nacua is back, but the offense is still struggling and now fellow wide receiver Davante Adams (hamstring) is on injured reserve and will miss at least four weeks (probably more). The defense is missing Myles Garrett (on IR with a knee problem) and Trent McDuffie (out with a groin issue). As such, my Rams vs Raiders prediction is for the home team to cover.

Regardless of their current skid, the Raiders have overachieved so far in 2026. Veteran quarterback Kirk Cousins is quietly playing very good football, while the defense can send Maxx Crosby, Quay Walker and Nakobe Dean to get after Rams 38-year-old QB Matthew Stafford. Moreover, it's not like Las Vegas' losing streak has been a shameful one. Two of the recent setbacks have come by three points against both Kansas City and Buffalo. In six games this year, the Raiders have lost by more than a field goal just once. I’m not saying they are going to win outright, but 5.5 points may be more than enough to cover.

Los Angeles Rams vs Las Vegas Raiders prediction: Raiders +5.5 (-115) available at time of publishing. Playable to +4.5.

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