49ers vs Rams Anytime TD Scorers: Best Picks and Predictions
The first-ever regular-season game to be played in Australia will be on Thursday Night Football in Week 1, with NFC West rivals, the 49ers and Rams, going head-to-head. Both teams come in revamped, with the Rams as Super Bowl favorites and the 49ers likely to have Mike Evans and George Kittle healthy enough to play. Let's dive into our 49ers vs Rams anytime touchdown scorer best bets, while you can also check all our NFL picks for every game in Week 1 and throughout the entire 2026 season!
Check out our full 49ers vs Rams prediction for expert picks on the side and total
49ers vs Rams anytime touchdown scorer best bet: Blake Corum (+150)
Odds available at DraftKings Sportsbook at time of publishing.
Look away, Kyren Williams bettors and fantasy owners, as I'm predicting Blake Corum will again be a vulture of Williams' workload, especially in the red zone. Corum had 25 rush attempts inside the top 20-yard line last season, resulting in five touchdowns. He adds to the long list of lethal weapons at MVP Matthew Stafford's disposal, headlined by Puka Nacua, whose status is still in question for Week 1, due to off-field allegations. The Rams' 26.5 implied team total will likely be the highest of any team, so backing one of their weapons at +150 is an easy button to click.
Find out Prop Holliday's best 49ers vs Rams player prop bet, targeting a play at +525 odds!
49ers vs Rams anytime touchdown scorer best bet: Deebo Samuel (+350)
Odds available at FanDuel Sportsbook at time of publishing.
Deebo Samuel returns to the 49ers after a year in Washington, where he was targeted 99 times, scoring five times through the air and once on the ground. He's now back with Kyle Shanahan, who is one of the best play-callers in football and elite at getting his best players the ball in space. Shanahan should have plenty of ammo to throw at the Rams, including Samuel. Though he'll be behind Christian McCaffrey, George Kittle, and Mike Evans, and potentially rookie De'Zhaun Stribling in terms of workload, Deebo offers first-class playmaking ability.
Go big on TNF with our expert's 49ers vs Rams Same Game Parlay for tonight at +410
NFL Week 1 Picks
Check out our expert NFL predictions for the Week 1 matchups below:
