College Football Picks

Get free college football picks for the best action throughout 2025-26 season, including college football picks against the spread, straight-up, money line picks, and total picks (over/under). Our data-devouring experts find you the best betting trends and NCAAF picks this week.

Read More
Filter Picks
Filter Picks
Bet Type
Experts
Confidence Rating
7:30 PM ET
Today
ESPN
Oregon Ducks
Indiana Hoosiers
Oregon
Indiana
Point Spread Pick
Oregon +4.5(-118)

The 2nd round of the College Football Playoff is behind us, and there are now just 4 teams remaining in the pursuit of a National Championship. Back on New Year’s Day, the 5th-seeded Oregon Ducks defeated Texas Tech to advance to this semifinal round, while the top-seeded Indiana Hoosiers rolled through Alabama in impressive fashion just a few hours later. Which of these teams will come out on top in the Peach Bowl on Friday and advance to the National Championship game? It’s almost time to find out. 

You could convincingly make the case that these are the 2 best teams in the country at the moment, and while it’s hard to ignore what we’ve seen from the Hoosiers over their last few contests, the basic market fundamentals clearly point to Oregon as the side in this game at the current number. For starters, it’s clear that a wager on Indiana in this game is buying the Hoosiers at the peak of their market value, while the Ducks are still being priced like a lesser team than they were a few months ago, which I just don’t believe is the case. After all, Oregon was a 7-point favorite against Indiana at Autzen Stadium back on October 11, which would roughly make this a line move of over 8 points since the first meeting between these teams. While Indiana deserves to be priced as the best team in the field, I’ve certainly upgraded Oregon following its dominant showing against Texas Tech, a team that is significantly better than an Alabama team that essentially quit after Indiana took an early double-digit lead in the Rose Bowl.

There’s no doubt that the Ducks played their worst game of the season by some distance in that first meeting, and they still were tied midway through the 4th quarter. Now, Dan Lanning’s group appears to be playing its best football of the season on defense, and the offense can hone in on making the necessary schematic adjustments to fix what went wrong in the previous meeting. It certainly won’t be easy against Heisman Trophy-winning quarterback Fernando Mendoza and the Hoosiers’ extremely balanced offense (2nd in success rate, 2nd in EPA per play, 3rd in points per drive) and the Indiana defense has also been a top-5 unit in the sport over the course of the season. However, given the fact that Oregon’s offense just had to face the best defensive front in the nation, I’m expecting a much better effort from the Ducks on the ground in this one, which was something they were able to do successfully for a decent chunk of the first meeting against Curt Cignetti’s defense.

Will Stein’s offense should also finally be getting Evan Stewart back for this game, which makes this the healthiest that Oregon’s deep group of pass-catchers (Dakorien Moore, Kenyon Sadiq, Malik Benson, Gary Bryant Jr., etc.) has been all season. With that in mind, as long as Dante Moore is able to play to his strengths and avoid making some of the mistakes he made in the first meeting, the Ducks should be able to grind out scoring drives and potentially even strike for some explosive plays downfield. Look for Oregon to empty the tank and pull out all the stops schematically on both sides of the ball in a game that could come down to the final possession.  

Oregon vs Indiana prediction: Oregon +4.5 (-118) available at time of publishing. Playable to 3.5.

You can bet on our Oregon vs Indiana pick with BetMGM, where right now new users can activate your new BetMGM account ⚡ and receive $150 in bonus bets INSTANTLY if your first $10+ wager is a winner!

Game Totals Pick
Over 46.5(-110)

At first glance, I thought I was going to be targeting the under in this game, much like I did for both teams in their quarterfinal matchups. However, I’m actually more inclined to look at the over in this game now that the total has come down a bit from the opening number. While both defenses are among the best in the nation, these offenses should be able to implement some schematic adjustments from the first game and improve on their respective performances. While neither offense played all that well back in that October meeting, the game still finished with 50 total points, and that was with each side squandering a few scoring chances. Now, the Ducks will get to showcase their speed on a fast track against an Indiana defense that loves to play its safeties deep, giving the opponent plenty of room to move the ball with the short and intermediate passing game — a mainstay in Will Stein’s offense.

On the other side, the Hoosiers offense was able to generate consistent success on the ground in the previous matchup, and that should continue into this game given how well Indiana’s offense line has played all year. The Oregon secondary is excellent, but this is the best wide receiver duo the Ducks have played, so it’s reasonable to assume that they’ll give up a few big plays here and there as well. Let’s roll with the over now that we’re under a key number.

Oregon vs Indiana pick: Over 46.5 (-110) available at time of publishing. Playable at that number.

If you’re looking for a new sportsbook for the football season, we recommend checking out Fanatics Sportsbook. New users can get $250 in FanCash INSTANTLY when they make their first $50 wager! Join Fanatics Sportsbook, where you can bet on our Oregon vs Indiana predictions.

Same Game Parlay
Money Line
Oregon Win
Anytime Touchdown Scorer
E. Sarratt (IND) to score a TD

Oregon Ducks ML over Indiana Hoosiers (+150)

There’s no doubt that the Ducks played their worst game of the season by some distance in that first meeting, but they should be able to hone in on making the necessary schematic adjustments to fix what went wrong in the previous meeting. It certainly won’t be easy against Fernando Mendoza and the Hoosiers’ extremely balanced offense (2nd in success rate, 3rd in points per drive), and the Indiana defense has also been a top-5 unit in the sport over the course of the season. However, given the fact that Oregon’s offense just had to face the best defensive front in the nation, I’m expecting a much better effort from the Ducks on the ground in this one, which was something they were able to do successfully for a decent chunk of the first meeting against Curt Cignetti’s defense.

Will Stein’s offense should also finally be getting Evan Stewart back for this game, which makes this the healthiest that Oregon’s deep group of pass-catchers has been all season. With that in mind, as long as Dante Moore is able to play to his strengths and avoid making some of the crucial mistakes he made in the first meeting, the Ducks should be able to grind out scoring drives and potentially even strike for some explosive plays downfield against an Indiana secondary that can be had via the deep ball. Ultimately, I’m anticipating that Oregon will empty the tank and pull out all the stops schematically on both sides of the ball, so I’ll back the Ducks on the money line in this spot.

Elijah Sarratt (IND) anytime touchdown scorer (+110)

I have been riding the Elijah Sarratt anytime touchdown scorer train for most of the season, and I’m certainly not hopping off now. Sarratt is one of the best receivers in the nation and he’s done nothing but light up defenses in both conference play and the College Football Playoff. Sarratt has racked up 13 touchdowns on the season, and he’s tallied at least 1 touchdown reception in each of his last 8 games played.

While Sarratt is expected to be shadowed by Oregon’s excellent true freshman cornerback Brandon Finney, he put up 8 receptions and 121 receiving yards and a touchdown in the first meeting between these teams, and at least half of that came against Finney. Let’s roll with the top Hoosiers receiver to record another touchdown.

College Football Picks This Week

With so many conferences and hundreds of matches played every weekend, the biggest test with any college football picks is unearthing those hidden gems. Here at Pickswise, that is exactly what we do. By focusing on the Power conferences and the Top-25 teams, along with a select number of other matches, our experts can focus on the key games and leave no stone unturned in our research. Pickswise is the home of free NCAAF picks, and we break down all of today’s college football action, with each pick coming with accompanying analysis, including all of the key stats, trends, and reasons for our pick.

Be sure to check back each week during the season for all of our top college football picks today.

Expert College Football Picks Against The Spread (ATS)

The most popular college football pick is against the spread (ATS). Against the spread betting isn’t about picking a winner of the football game, it’s about picking the team who will cover the spread.

Let’s say you bet your money that Team A covers the spread (wins by a certain amount of points), Michigan State -6.5 for example. Or that Team B will cover the spread (keep the game closer than oddsmakers expect), Ohio State +6.5. If Michigan State beat Ohio State 30-27, then Ohio State covers the spread, and underdog backers are cashing tickets with +6.5 on Ohio State.

Against-the-spread betting is extremely popular in football and that’s one of the main reasons why it’s one of the most popular college football picks on our site.

NCAA Football Today – Today’s NCAAF Picks

At Pickswise we cover all of the Power NCAA football today, with full game previews, picks, and betting analysis brought to you by our college football experts. A typical college football season runs from August to December and is preceded by the College Football Bowl Season and College Football Playoff, culminating in The College Football Playoff National Championship game in January.

When Do You Post Your College Football Picks

We post our college football picks for this weekend a couple of days before the scheduled match. We post our picks early enough so that you can digest the information, do your own research into the match, and make sure you get the best lines and odds for that particular pick. Like anything in sport, some things are unpredictable, and on occasion, we may choose to delay posting a pick if there is something like a key injury or likely conditions that could have an impact on the outcome of the match, or our pick itself. Check back leading up to the weekend every week throughout the season to see what NCAAF Picks we have for today.

Free Expert NCAAF Picks

All of our NCAAF picks are absolutely free, all season long. We have a team of expert NCAAF handicappers on hand to preview the very best of the Power conference or Top-25 ranked match, every week, all season long. Each of these previews comes with our experts’ NCAAF pick on the three main markets (Money Line, Spreads & Totals) with a full breakdown of why they like a particular side, as well as a confidence rating for each individual NCAAF pick. You can find every NCAAF pick throughout the season right here on the NCAAF Picks page, or check out our NCAAF Parlays for even more insight into betting better on NCAA Football this week.