College Basketball Picks

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College basketball picks for the 2025/26 season. Get college basketball expert picks against the spread and totals for the best matchups throughout college basketball every day. We also have you covered for the best action throughout March Madness 2026. Check out our College Basketball Best Bets for our top plays on today’s games.

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7:30 PM ET
Tomorrow
TBS
Iowa Hawkeyes
Nebraska Cornhuskers - NCAAB
Iowa
Nebraska
Money Line Pick
Iowa Win(+105)

It wasn’t easy for either team to advance to the Sweet 16, but now the #9 seed Iowa Hawkeyes and the #4 seed Nebraska Cornhuskers are set to face off — with the winner advancing to the Elite Eight. Iowa pulled off a huge upset over the #1 seed Florida Gators in a thrilling matchup. Alvaro Folgueiras knocked down a 3-pointer with 4 seconds left to give the Hawkeyes a 73-72 lead that ultimately sealed the deal. Iowa shot 51% from the floor and did a great job limiting Florida on the glass, which played a key role in the upset. As for Nebraska, it held on against Vanderbilt — with Braden Frager converting a layup with just 2 seconds remaining to secure a 74-72 victory.

The Hawkeyes will need Bennett Stirtz to figure things out in this matchup against Nebraska. Stirtz struggled against Florida, scoring just 13 points while going 0-for-9 from 3 and 5-of-16 from the field. These are 2 Big Ten opponents that are familiar with one another. During the regular season, Iowa defeated Nebraska 57-52 on February 17; Nebraska got revenge on March 8 with an 84-75 overtime win. Both teams rank among the best defensively in their conference, with Nebraska allowing 65.8 points per game and Iowa close behind at 66. The Cornhuskers do hold a slight rebounding edge (37 to 32), but Iowa has been more efficient offensively — shooting 48.9% from the field compared to Nebraska’s 46.6%. This game could go either way, but based on recent form, Iowa looks like the more complete team. The Hawkeyes showed resilience and composure in their win over Florida and are peaking at the right time. Give me Iowa to win a close one and punch its ticket to the Elite Eight.  

Iowa vs Nebraska prediction: Iowa ML (+105) available at time of publishing. Playable at that number.

Vote on who will win!

9:45 PM ET
Tomorrow
CBS
Arkansas Razorbacks
Arizona Wildcats - NCAAB
Arkansas
Arizona
Point Spread PickBest Bet
Arizona -7.5(-115)

The West Region features the #1 Arizona Wildcats vs the #4 Arkansas Razorbacks. Arizona pulled away from Utah State to get here, while Arkansas had to battle the whole way to put away a feisty High Point squad. This line originally opened at -9.5, and that would be the largest tournament deficit John Calipari has ever faced. Since then, it has pushed back down to -7.5 — and that is taking us into hammer territory. I think Vegas had this right in the first place — and this is a spot where we can bet a #1 seed while fading the public, which is backing the Hogs at a 70% clip at the time of this writing. Give me Arizona.

Arkansas plays super fast and has one of the best guards in the country in Darius Acuff Jr. What people fail to recognize with Arizona, however, is that it boasts a top-3 defense according to both KenPom and Torvik. The Hogs will still score, but the Arizona defense is a championship-level difference-maker. Arkansas attacks the rim a ton, but Arizona ranks #2 in the country at defending the rim. That’s a matchup problem for Arkansas. The Wildcats make very few mistakes and they have talent in waves. Eventually, I suspect it will overwhelm Arkansas. I am hammering this at -7.5 and playing it out to the original line of -9.5.

Arkansas vs Arizona prediction: Arizona -7.5 (-115) available at time of publishing. Playable to -9.5.

7:10 PM ET
Fri Mar 27
CBS
St. John's Red Storm - NCAAB
Duke Blue Devils
St. John's
Duke
Point Spread Pick
St. John's +6.5(-110)

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The St. John’s Red Storm and Duke Blue Devils meet in the Sweet 16 of the NCAA Men’s Basketball Tournament, setting up a compelling clash between experience and elite talent. St. John’s enters at 30-6, riding momentum after a dramatic win over the Kansas Jayhawks to reach this stage, and they’ve now won 21 of their last 22 games. The Red Storm average 81.1 points per game while allowing 69.4, with their defensive identity driving success. They generate over 7.8 steals per game and rank among the stronger teams nationally in turnover margin, consistently creating extra possessions. Forward Zuby Ejiofor leads the team with 16.3 points and 7.2 rebounds per game, anchoring a physical frontcourt that can disrupt opposing offenses. Perhaps the biggest factor is head coach Rick Pitino, who owns a remarkable 12-1 record in Sweet 16 games, highlighting his ability to prepare teams for this stage and maximize execution in high pressure tournament settings.

Duke enters at 34-2 and has been one of the most efficient teams in the country on both ends, averaging 81.9 points per game while allowing just 63.1, one of the best defensive marks nationally. The Blue Devils shoot 49% from the field and dominate the glass with 40.4 rebounds per game, led by freshman standout Cameron Boozer, who averages 22.5 points and 10.2 rebounds. Duke’s ability to control the boards—particularly on the offensive glass—creates consistent second chance opportunities and puts pressure on opposing defenses. While Duke’s talent and efficiency make them the rightful favorite, this matchup presents a tougher test than the spread suggests. St. John’s defensive pressure, ability to force turnovers, and experienced leadership give them a strong foundation to compete throughout the full 40 minutes. If the Red Storm can limit second-chance points and control tempo, they have the tools to keep this game close deep into the second half despite Duke’s firepower.

St. John’s vs Duke Prediction: St. John’s +6.5 (-110) available at time of publishing. Playable to +5.5.

7:35 PM ET
Fri Mar 27
TBS
Alabama Crimson Tide
Michigan Wolverines - NCAAB
Alabama
Michigan
Point Spread Pick
Michigan Win -10.0(-115)

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This isn’t the Rose Bowl, but this is a game tailor made for the Wolverines in the Sweet 16. The Tide live and die by their offense and shooting the three. Michigan however, can beat you in more ways than one. The Maize and Blue can play with pace, they score in the interior, they have perimeter capacity, and they can slow it down and defend well. The Wolverines have all the makings of a national champion, they are efficient, physical, and downhill. That’s bad news for Alabama who has only one trick up its sleeve.

The Tide rolled past Hofstra and a tired Texas Tech, but this is an entirely different assignment. The Wolverines can slow Bama down, they can minimize their three-point operations to less attempts and less success, and they can take advantage of Alabama’s vulnerabilites to defend. Not only is this a contest where Michigan should win it, they can do so emphatically. It’s alluring to back the hot offensive team with points, such a wager is one that is a commodity come tourney time, but it’s nothing to hang a hat on. Against a balanced and disruptive entity like the Wolverines, Alabama can hit a wall and be run over at the same time. Michigan moves onto the Elite Eight with style.

Alabama vs Michigan prediction: Michigan -10 (-115) available at time of publishing. Playable to the number.

The Home Of Free College Basketball Expert Picks For The 2025/26 Season

College basketball picks for the 2025/26 season. Our experts crunch the numbers, betting trends, injury reports, and much more to produce the best free college basketball picks and every day throughout the season and into March Madness itself. 

Unlike many places, here at Pickswise, we have you covered all season long, whether it’s non-conference play, conference play, championship week, or March Madness, our NCAA basketball picks have you covered. Our College Basketball picks include a pick against the spread as well as on the points totals market, and both come with expert analysis and the key stats and trends. Check out our free college basketball picks today, and get all the latest College Basketball Odds

Free College Basketball Picks Explained

With 353 Division I college basketball teams there are plenty of opportunities to find good value college basketball picks. With so many games played each day it is impossible for sportsbooks to get the lines correct for every single match. As sports bettors, this gives us a great opportunity to research the games, and find those edges to better serve our chances of long-term wagering success. That’s precisely what we do here at Pickswise. Our dedicated college basketball team covers every morsel of NCAAB action, leaving no stone unturned in the search for the best value picks for the top CBB action, and NCAA Basketball Futures, all of which are accompanied with full analysis, for free, only here at Pickswise. 

Free College Basketball Picks Against The Spread (ATS)

One of the more popular college basketball wagers is betting against the spread (ATS). Against the spread betting isn’t just picking a winner of the basketball game, it’s about picking the team who will win by a set margin, known as covering the spread.

Let’s say you bet your money that Team A covers the spread (wins by a certain amount of points), Duke -6.5 for example. Or that Team B will cover the spread (keep the game closer than oddsmakers expect), Kentucky +6.5. If Duke beat Kentucky 64-60, then Kentucky would cover the spread, and underdog backers will cash their tickets on Kentucky +6.5 points.

The disparity is a big thing in many college basketball matchups and as such Moneyline betting will often see small odds about a favorite. Betting against the spread is very common, for this reason. It allows bettors to wager on the big favorites, who are expected to win,  at better odds, but also the opportunity to bet the underdog. These are the main reasons why college basketball against the spread betting is so popular, but it is also  one of our most popular college basketball picks on Pickswise. This is because knowing when an underdog might keep a game close or when potentially evenly matched teams might have blowout is very hard to predict without all the research, expertise, analysis and data our team has at its disposal. 

Free College Basketball Totals Picks (Over/Under)

The other main NCAAB wager is the totals which are simply betting over or under a set number of points in a game. This market is seen to be one of the easier markets to beat the book if you can get to grips with some of the most important statistics which contribute to how many points will be scored in a ball game.

Some of the most important factors to consider when handicapping totals in basketball are the number of possessions per team in a game and the pace of play. Our experts at Pickswise consider these key angles as well as matchups, injuries, and betting trends to determine which side of the line has the best chance of hitting, and we have a strong record of getting this right.

CBB Picks

All of our CBB picks are posted right here on the college basketball picks page, all season long. Our experts post their top CBB picks, along with a detailed analysis including the key stats and matchups ahead of that game. Our CBB picks include a pick on the money line, spread, and totals for every match we cover, check them out today. we also have reliable College Basketball Predictions daily throughout the season.

College Basketball Parlay Picks

With so many games available to bet on there’s always great potential for College Basketball Parlays. You could make it a multi-game pick combining different money line or against the spread bets or you might want to get creative with other bet types within a single game parlay. Remember when you parlay you need all included bets to win to cash your wager, but with all those odds multiplied it can be very lucrative.

The statistical method for NCAA Basketball Picks

Just like pro sport teams, the college basketball teams that have success often take a very statistical approach to their decision making, so why wouldn’t you do the same for your bets on them?

At Pickswise we don’t believe in chance bets, our expert team comb through all the data, do all the analysis and provide all their research so you can have confidence in our College basketball picks.

Andrew Wilsher, Pickswise Managing Editor

More Than Just College Basketball Picks

At Pickswise we don’t just cover College Basketball Picks, collegiate sports fans will be pleased to know we also have free weekly expert College Football Picks too.

We also have expert handicappers for each of the professional sports in North America including our NFL Picks, MLB Picks, NBA Picks, and NHL Picks. Check out all of our sports betting picks today.