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College basketball picks for the 2025/26 season. Get college basketball expert picks against the spread and totals for the best matchups throughout college basketball every day. We also have you covered for the best action throughout March Madness 2026. Check out our College Basketball Best Bets for our top plays on today’s games.

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6:40 PM ET
Today
truTV
Prairie View A&M Panthers
Lehigh Mountain Hawks - NCAAB
Prairie View A&M
Lehigh
Point Spread Pick
Lehigh -2.5(-115)

Teams that score and play with tempo are fun to watch. They also get a lot of love from the betting market. That’s Prairie View A&M in this situation. The Panthers also have been on a sick heater against the spread — 10 straight covers and an incredible march through the SWAC to land PVAM in the First Four. Where were the Panthers 2 weeks ago? Sitting at 11-17 staring down the barrel of a bottom-tier seed in the conference tournament before they did the unthinkable.

That narrative will curry a lot of market favor. The market is investing in the story as much as the allure of a fast-paced offensive team that can run it up and down the floor. But this isn’t the SWAC; this is the Big Dance, and tempo teams don’t exactly fare well. Enter Lehigh. The Mountain Hawks quietly orchestrated their own uncanny run to the First Four on the heels of solid defense that carried them through the Patriot League Tournament. Unlike the Panthers, the Hawks play slow and let the game come to them. This is exactly the sort of side that A&M doesn’t want to see in a play-in game to make the main bracket. But here we are. The Mountain Hawks will turn this into a grind and a knuckle-dragging rock fight that will throw the Panthers out of rhythm. This is the perfect spot to back Lehigh. Let’s lay the points.

Prairie View A&M vs Lehigh prediction: Lehigh -2.5 (-115) available at time of publishing. Playable to -3.

9:10 PM ET
Today
truTV
Miami (OH) Redhawks - NCAAB
SMU Mustangs - NCAAB
Miami Ohio
SMU
Point Spread Pick
Miami Ohio +7.0(-120)

Miami Ohio couldn’t have asked for a better regular season, finishing a perfect 31-0 while leading the MAC in scoring. However, that momentum came to a halt after a quarterfinal exit against UMass in the MAC Tournament. Now the RedHawks will look to put that behind them and prove their undefeated regular season wasn’t a fluke as they prepare to face SMU in the First Four matchup. The Mustangs didn’t close out the season the way they had hoped, dropping 5 of their last 6 games — which includes an opening-round loss in the ACC Tournament to Louisville 62-58. The Mustangs also struggled away from home, going just 5-10 on the road and at neutral sites this season. That said, both teams bring high-powered offenses into this matchup. Miami Ohio averaged 90.7 points per game in conference play and SMU put up 84.2 in the ACC. 

Miami Ohio does a great job moving the ball and creating open looks, but the level of competition is a concern, as they didn’t face a Quad 1 opponent this season. SMU also plays at a fast pace and can score in bunches while also bringing a physical presence inside. That interior strength could be a major factor in this matchup, especially after Miami Ohio was dominated in the paint by UMass (54-30) and out-rebounded 41 to 24 in their tournament loss. Even with SMU’s advantage inside, its struggles away from home and its defensive issues can’t be ignored. With Dayton just about an hour from Miami Ohio’s campus, the RedHawks should have plenty of fan support in this matchup. This game sets up to be a fast-paced, high-scoring battle, with SMU looking to control the paint. However, I expect the RedHawks to generate open looks from the perimeter and knock down shots from deep, which should allow them to keep this game close. 

Miami Ohio vs SMU prediction: Miami Ohio +7 (-120) available at time of publishing. Playable at that number.

12:15 PM ET
Tomorrow
CBS
TCU Horned Frogs
Ohio State Buckeyes
TCU
Ohio State
Point Spread Pick
Ohio State -2.5(-115)

#9 seed TCU will open the NCAA Tournament against the #8 seed Ohio State in what should be an exciting matchup. The Horned Frogs closed the season strong on both ends of the floor, winning six of their last seven games. Ohio State has also been playing well, winning four of its last five, including a near upset of Michigan in the Big Ten Tournament. Both teams bring plenty of talent, but the edge goes to Ohio State – and here’s why. 

Bruce Thornton is one of the top guards in the country, averaging 20.3 points and 5.1 rebounds per game. He’s a tough matchup for any defense, and he’s not alone. The Buckeyes also feature John Mobley Jr. (15.7 PPG), Devin Royal (13.7 PPG), and 7-foot center Christoph Tilly, who adds 11 points per game. The Horned Frogs have plenty of depth of their own, with four players averaging double digits, and they thrive on forcing turnovers with their defensive pressure. However, Ohio State holds a clear edge in efficiency. The Buckeyes are shooting  49.3% from the floor compared to TCU’s 44.8%, and they’re also more reliable at the free-throw line, hitting 77.5% compared to the Horned Frogs 70.8%, which could be critical late in the game. Defensively, both teams are strong with the Buckeyes holding opponents to 72.8 points per game compared to the Horned Frogs 72.1. While Thornton hasn’t played in an NCAA Tournament game, he has the playmaking ability and discipline to handle the pressure. The Buckeyes have strong perimeter defense and should be able to shut down their 3-point shooting, and also limit TCU’s success in the paint, with Christoph Tilly and Devin Royal protecting the interior and closing off driving lanes. Look for Ohio State to knock down critical free throws late and cover the small spread before advancing to the next round of the NCAA Tournament.  

TCU vs Ohio State prediction: Ohio State -2.5 (-115) available at time of publishing. Playable at that number.

12:40 PM ET
Tomorrow
truTV
Troy Trojans - NCAAB
Nebraska Cornhuskers - NCAAB
Troy
Nebraska
Point Spread PickBest Bet
Troy +13.0(-115)

The Troy Trojans and the Nebraska Cornhuskers will meet on Thursday for round one of the NCAA Tournament. It will be the second game to tip off in this year’s tournament, and we could see the first upset early in the big dance. Troy is a 13-point underdog in this game but will be a trendy upset pick in the round of 64. Nebraska started the season 20-0 but has finished the season going just 6-6. The Cornhuskers will look to win their first NCAA Tournament game in program history, but I expect that the Trojans will keep this one close.

My best bet of the game is Troy +13. 13 feels like too many points for a team that played well against high level opponents this year. Troy beat San Diego State earlier in the season and lost to USC in triple overtime. They beat tournament teams Akron and Furman as well, so will not be shocked by Nebraska’s talent. Nebraska’s offense has not been good recently, so I do not expect Nebraska to overpower Troy offensively. Since February 1st, the Cornhuskers offense is ranked #132 in adjusted offensively efficiency. Combine that with the slow pace of play expected in this one, I see Troy keeping it within the number.

Troy vs Nebraska prediction: Troy +13 (-110) available at time of publishing. Playable to 10.

1:30 PM ET
Tomorrow
TNT
South Florida Bulls- NCAAB
Louisville Cardinals - NCAAB
South Florida
Louisville
Point Spread PickBest Bet
South Florida +6.5(-120)

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After a long and eventful regular season and the beautiful chaos of Championship Week, the best time of year is finally here. March Madness has arrived and with it comes a plethora of games for us to dig into over the course of a couple of action-packed days. One of the first games on Thursday’s slate comes in the East Region between Louisville and South Florida in what should be a battle of teams that mirror each other a bit in certain areas. The Bulls are a side that I’ve enjoyed backing down the stretch and South Florida comes into this contest having won 11 straight games, with most of those victories coming by double digits. Conversely, Louisville is on the opposite end of the spectrum, having dropped 4 of its last 8 games after bowing out in the quarterfinals of the ACC tournament. There are some serious warning signs that suggest the Cardinals should be on upset alert, and this is a solid spot to take a shot on USF in a matchup where they should hold some crucial edges.

The Bulls are unlike some of the other popular mid-major picks that you’ll see in many brackets this time of year, and it’s largely due to the fact that their roster is littered with high-major transfers and veteran players who are not new to this sort of high-pressure situation. Bryan Hodgson’s team starts a trio of excellent seniors, including Izaiyah Nelson — the AAC Player of the Year. The Bulls typically employ a 7-man rotation, and 5 of those players are upperclassmen who have played dozens of games at this level. There won’t be an intimidation factor in this game, and given the fact that South Florida has been a top-35 team since February 1 per BartTorvik, the Bulls are certainly trending in a better direction compared to their opponent.

It all starts on defense, with South Florida sitting inside the top 40 in adjusted efficiency and 24th in two-point percentage defense on the year. On offense, the Bulls are a dominant unit in transition in league play, and we saw them use that comfort of playing at a very fast tempo to great advantage during the conference tournament. Furthermore, South Florida should be very competitive in the shot volume battle in this matchup, seeing as its ranked 6th in offensive rebounding percentage on the season, while Louisville sits at 168th over the last 2 months in that same statistic (BartTorvik). On the other side, Louisville has struggled away from home all season long, and the Cardinals’ are also at the mercy of a nagging lower-back injury that has caused Mikel Brown Jr. to miss 10 games this season. If Brown Jr. is unable to play or is limited in this game, the Louisville offense would certainly take a major hit. Even if Brown is a full-go, I like the matchup for South Florida and think the Bulls can spring the upset. With that in mind, I’ll back USF with the points on Thursday.

South Florida vs Louisville prediction: USF +6.5 (-120) available at time of publishing. Playable to +5.

1:50 PM ET
Tomorrow
TBS
High Point Panthers
Wisconsin Badgers
High Point
Wisconsin
Point Spread PickBest Bet
High Point +10.0(-115)

The anatomy of an upset. We’re going to break it down. The Badgers are a team that lead with offensive first, play with pace, and love to attack from the perimeter. When it all goes well, Wiscy can put up 100 points and look unstoppable. But if the shots don’t fall? Wisconsin can be in trouble. Particularly, when the opponent plays with pace and score like the Panthers can.

If you are filling out your bracket, High Point is worth being written down to spring the annual 5 vs. 12 upset. From a betting perspective, getting the Panthers with the points is one of the better plays you will encounter perhaps in any sport, this week. We don’t even need High Point to win to cash this ticket, but they can win. That’s the whole point. Wisconsin is tagged by many to be a dark horse in the West region. Analysts love the prospect of an Arkansas-Wisconsin smokeshow in the Round 32. The problem is that horse may never get out of the gate. But because High Point has gone to March Madness two years in a row and hasn’t won a game yet in school history, it seems unfathomable for such events to unfold. That’s how brackets are broken and how winning plays are uncovered. A Panthers victory would be inconceivable to many but the set-up is there, and all we need is the Panthers to compete in a game that I believe they will win outright.

High Point vs Wisconsin prediction: High Point +10 (-115) available at time of publishing. Playable at that number.

2:50 PM ET
Tomorrow
CBS
Siena Saints - NCAAB
Duke Blue Devils
Siena
Duke
Point Spread Pick
Siena Win +28.0(-115)

The Blue Devils are a commodity. The Saints? Not so much. Duke is a top seed in the bracket and one of the game’s titans. Siena? They snuck into March Madness by taking down Merrimack in the MAAC Championship to earn a #16 seed. Point out where Duke is on the map, and most fingers will land in Durham, North Carolina. Siena? Some may think that they are some small college from the West Coast. They are actually from Poughkeepsie, New York.

The point that I am trying to make is that Duke almost certainly commands a premium to back them here and as a result, they are undoubtedly overvalued. Yes, the Blue Devils will win and advance. But by this margin? That’s a mystery. Let’s not forget who the Saints are. A team looking to do the unthinkable, the biggest game in their university’s history. This is a scenario where even if Duke goes up big, the Saints are going to empty the tanks which makes them a tough fade at this price. Gerry McNamara has turned this program around in a short period of time and in case any forget who Siena’s skipper is, he was the man that led Syracuse on a crazy run 20 years ago in this very tournament.  We are not saying an upset is on the horizon, but against a motivated underdog, an overlay is certainly likely.

Siena vs Duke prediction: Siena +28 (-115) available at time of publishing. Playable at that number.

4:05 PM ET
Tomorrow
TNT
North Dakota State Bison - NCAAB
Michigan State Spartans
North Dakota State
Michigan State
Point Spread Pick
North Dakota State +16.5(-115)

Tom Izzo and Sparty go together with March Madness like peanut butter and jelly. You will hear the rhetoric and hyperbole all tournament long: Michigan State is a Final Four contender because of their pedigree and their coaching. That’s true, but as is the case with teams like the Spartans, you pay to play when you back them. That is assuredly the case here.

Michigan State is a good team. North Dakota State? They won the Summit League. That’s not going to move the needle. Situationally speaking, this is not a good look for the Bison to win. We are talking about a top-25 scoring offense against a top-25 scoring defense. In March, the latter means more. But the question isn’t whether the Spartans are on upset alert or not, it’s whether they can cover. That’s a more trying debate. Even if Sparty rolls NDSU, there is backdoor potential at the minimum laying this number. MSU can be cruising late and a few baskets in the final frames can take a 20-plus point lead to where the Bison sneak in under the number. Bottom line, don’t lay this kind of wood. You are paying to do so and the price almost certainly is too expensive.

North Dakota State vs Michigan State prediction: North Dakota State +16.5 (-115) available at time of publishing. Playable at that number.

6:50 PM ET
Tomorrow
TNT
VCU Rams - NCAAB
North Carolina Tar Heels - NCAAB
VCU
North Carolina
Point Spread Pick
VCU +2.5(-115)

One of the more intriguing first round matchups on Thursday features the VCU Rams vs the North Carolina Tar Heels. The Rams rolled through the A-10 tournament, and they ended the season on a 6-game winning streak. The Tar Heels come into the tournament vulnerable, with star freshman Caleb Wilson out for the year. If you are shopping for an upset for your bracket, this would be a good spot to look. For bettors, there is still value here too, and I look for VCU to keep this game close at +2.5.

The Heels obviously still have lots of talent without Wilson, no doubt about that. Seth Trimble especially will step up and carry the load. But there is more here. In particular, this is a dangerous matchup for Carolina. VCU is an elite 3-point shooting team, and when they aren’t shooting threes, they are good at getting themselves to the foul line. While UNC does not foul a lot, they do struggle to defend the arc. If there is one tried and true formula for a first round upset, that is it—the ability for underdogs to make 3s. It is also worth noting that VCU beat Virginia Tech by 18 and nearly upended NC State, so they can go toe to toe with ACC squads. And those games were in November; the Rams have only improved since then. I like VCU in this spot.

VCU vs North Carolina prediction: VCU +2.5 (-115) available at time of publishing. Playable at that number.

7:35 PM ET
Tomorrow
truTV
Texas A&M Aggies
Saint Mary's Gaels
Texas A&M
Saint Mary's
Point Spread Pick
Saint Mary's -3.0(-120)

One of the harder games on the slate is Thursday evening’s South regional matchup between the Texas A&M Aggies and the St. Mary’s Gaels. The game will be played in Oklahoma City, which is a definite advantage for the Aggies, but the matchup itself favors the Gaels. We also have a serious conflict of styles, as the Aggies are a go-fast team, while St. Mary’s has consistently been among the most deliberate teams in the nation for several years now. Whoever controls the pace probably controls this game. Typically, the slow team grinds down the game and frustrates the fast team, and that is what I am looking for here. Give me St. Mary’s -3.

Bucky Ball worked for a little while in College Station, but as the Aggies slumped down the stretch, it was an indication that teams were figuring out how to counter their style of play. The problem for the Aggies in this matchup is that the things they do well are also things that St. Mary’s is good at stopping. The Aggies want to take a ton of 3s; the Gaels are top 40 in the country at defending the arc. The Aggies want to go fast, but the Gaels control the pace. The Aggies attack the rim, but the Gaels protect the rim at an elite level. They also clean up as many rebounds as anyone in the country. I think this is a favorable spot for St. Mary’s, and I think the slumping Aggies are in trouble here. It is hard to take a slow-paced team to win by much of a margin though.

Texas A&M vs St. Mary’s prediction: St. Mary’s -3 (-110) available at time of publishing. Playable at that number.

9:25 PM ET
Tomorrow
TNT
Penn Quakers - NCAAB
Illinois Fighting Illini
Penn
Illinois
Point Spread Pick
Illinois Win -24.5(-115)

The #3 seed Illinois will take on #14 seed Penn in the first round of this NCAA Tournament, and while this South Region is filled with potential upset candidates, this matchup shouldn’t be one of them. Illinois enters as the clear favorite and should be in control from the opening tip. The Fighting Illini bring a major advantage in both size and depth, which will be difficult for Penn to handle for a full 40 minutes. A key player to watch is David Mirkovic, who presents a tough matchup with his versatility. He’s averaging 13.4 points and 7.8 rebounds per game, and his ability to stretch the floor makes him even more dangerous. Mirkovic is shooting 37.1% from beyond the arc this season, meaning Penn won’t be able to simply pack the paint to slow him down. 

Penn is coming off an impressive overtime win against Yale in the Ivy League Championship, and while that momentum gives them confidence heading into the NCAA Tournament, this is a much tougher matchup against Illinois. On the season, the Quakers are averaging 76.1 points per game while allowing 73.3, and they’ve also struggled from the free-throw line, converting just 69.3%. TJ Power is coming off a massive performance against Yale, pouring in 44 points, but it’s to envision a repeat against a Fighting Illini defense that’s allowing just 69.8 points per game. Penn is 0-2 against Quad 1 opponents, and 1-4 against Quad 2 teams this year. Illinois has the size, length, and defensive discipline to make scoring much more difficult, especially for a Penn team stepping up in competition. Freshman Keaton Wagler will be tough for Penn to defend as he can beat you inside or from deep. When Penn faced Villanova, they lost by 27 points, and we can expect a similar outcome in this matchup. Look for Illinois to come out firing in the first round and not letting up as the game goes on, making it a long day for Penn. 

Penn vs Illinois prediction: Illinois -24.5 (-115) available at time of publishing. Playable at that number.

9:45 PM ET
Tomorrow
CBS
Saint Louis Billikens - NCAAB
Georgia Bulldogs - NCAAB
St. Louis
Georgia
Point Spread PickBest Bet
Georgia -2.5(-120)

As Thursday starts to wind down, we look to the Saint Louis Billikens vs the Georgia Bulldogs in an 8-9 matchup from Buffalo, NY. These teams both like to fly up and down the court, both operating at a top-20 pace nationally. A few weeks ago, Saint Louis was looking like a sneaky bracket buster, but that was before they closed the season at 4-4 over the final month. The Bulldogs had their struggles in the middle of the conference season, grinding out the SEC gauntlet. Still, I don’t love what I have seen from the Billikens lately, and that has me taking the Bulldogs at -2.5.

Georgia plays fast, but there is more under the hood. In particular, they thrive on pressure defense, turnovers, and transition scoring. They have at top-25 2-pt% because of how often they attack in transition. Saint Louis has some turnover issues, and if they can’t keep the Dawgs out of transition, it will be a problem. The hope for the Billikens is that they make a lot of 3s, which they can certainly do. I just wonder if they can do that against a high-pressure defense. This will also be the first power conference opponent all season for the Billikens, and I think they may get exposed. Call me suspicious, and give me the Bulldogs to cover.

Saint Louis vs Georgia prediction: Georgia -2.5 (-110) available at time of publishing. Playable to -4.5.

10:10 PM ET
Tomorrow
truTV
Idaho Vandals - NCAAF
Houston Cougars - NCAAB
Idaho
Houston
Point Spread Pick
Houston -23.5(-115)

The Idaho Vandals and the Houston Cougars will face off on Thursday for round one of the NCAA Tournament. This game is a late tip off in Oklahoma City following the Saint Mary’s and Texas A&M game. I do not expect this one to be a very close one as Houston should be able to handle Idaho with not many issues. The Vandals finished the regular season just 17-14 but went on a four-game winning streak to win the Big Sky Conference Tournament. The Big Sky has not fared well in the big dance as they are just 3-10-1 against the spread since 2010. I expect Houston to add to that bad record and cover the spread here.

Houston -23.5 is my best bet of the game because I do not see Idaho having any success against Houston’s high-level defense. The Cougars have an elite defense every year under Kelvin Sampson, and this year is no different. According to KenPom, Houston’s defense is ranked #5 nationally in adjusted defensive efficiency, #17 in effective field goal percentage and #10 in two-point percentage. The Vandals offense is ranked just #176 in adjusted offensive efficiency, so I expect them to struggle to score. They shoot a bunch of threes but only shoot 34.5 percentage from beyond the arc and will likely not be able to score much inside here. Take Houston to cover.

Idaho vs Houston prediction: Houston -23.5 (-110) available at time of publishing. Playable to -25.

12:15 PM ET
Fri Mar 20
CBS
Santa Clara Broncos - NCAAB
Kentucky Wildcats
Santa Clara
Kentucky
Point Spread Pick
Santa Clara +3.5(-110)

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After a long and eventful regular season and the chaos of Championship Week, the best time of year is finally here. March Madness has arrived and with it comes a plethora of games for us to dig into over the course of a couple of action-packed days. The opening game on Friday’s slate features an intriguing matchup between the Santa Clara Broncos and Kentucky Wildcats in a battle between a couple of teams that are trending in opposite directions. While Kentucky is likely to be a popular choice in this game, there is certainly an opportunity for the WCC finalists to compete in this game, and potentially win outright against an overvalued SEC opponent.

Santa Clara is a team that I’ve been high on all season long, and the Broncos not only showed their prowess in WCC play, but they also played really well in the nonconference portion of theis schedule. In fact, Herb Sendek’s team knocked off the likes of Minnesota, Xavier, Nevada and McNeese State, while losing to St. Louis by just 1 point in a neutral site game. The Broncos consistently played up to their competition level this season, and if they had managed to upset St. Louis or Arizona State (a game they lost by just 3 points), they likely would be sitting on the #9 seed line, instead of a bubble team on the #10 seed line. Santa Clara boasts one of the best offenses at the mid-major level, with the Broncos ranking inside the top 15 in adjusted efficiency and top 40 in 2-point percentage (BartTorvik). This is a team that also generates offensive rebounds at an elite level (ranked 19th nationally) and should be able to thrive against a Kentucky defense that is outside the top 150 in rebounding rate and is an abysmal 233rd in free-throw rate allowed on the season.

On the other side, it’s fair to expect the Wildcats to have the majority of the crown for this one, seeing as the game is being played in St. Louis. However, this still doesn’t profile as a good matchup for Mark Pope’s team. For starters, Santa Clara’s pressure defense should be able to force the Kentucky offense into some turnovers, which is an issue the Wildcats have struggled with all season. If the pace of this game starts to increase, that also favors a Santa Clara team that likes to get out and run in order to generate early offense. I do have some concerns with the Broncos’ high foul-rate and Kentucky should be able to generate success against the Santa Clara interior defense. However, the Broncos do a pretty decent job of defending the 3-point line, and Kentucky has not shot the ball well from beyond the arc this season (167th in 3-point percentage). In a game that should come down to the final minutes, I’ll side with the underdog Broncos catching over a possession.

Santa Clara vs Kentucky prediction: Santa Clara +3.5 available at time of publishing. Playable to +3. 

12:40 PM ET
Fri Mar 20
truTV
Akron Zips
Texas Tech Red Raiders
Akron
Texas Tech
Point Spread Pick
Akron +8.5(-110)

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After a long and eventful regular season and the beautiful chaos of Championship Week, the best time of year is finally here. March Madness has arrived and with it comes a plethora of games for us to dig into over the course of a couple of action-packed days. One of the first games on Friday’s slate features a team that profiles as a March sleeper in the Akron Zips, and there is an opportunity for the champions of the MAC to make a splash against a Big 12 opponent.

Akron has been in this spot before, as this is the third straight year that John Groce’s side has made the Big Dance, and they should be able to learn from their previous experiences in this setting. Led by Tavari Johnson and Shammah Scott in the backcourt, the Zips have veteran leaders all over the floor and an offense that has the capability to do major damage both from the perimeter and in the paint. Akron boasts one of the most efficient mid-major offenses inside of 15 feet, and the Zips can also knock down outside shots at nearly a 40% clip. Furthermore, Akron should be able to create second-chance opportunities with its prowess on the glass, while Texas Tech has taken a massive hit in the rebounding department over the last month (288th in defensive rebounding rate). On the other side, it’s also worth mentioning that while Texas Tech has played admirably without the services of JT Toppin (out for the season with a torn ACL), the Red Raiders have now become incredibly reliant on their backcourt play and outside shooters. To their credit, Grant McCasland’s team has shot the lights out from beyond the arc in recent weeks, but that just signals to me that regression is certainly coming due for a team that is top 10 in both 3-point rate and 3-point percentage over the last month. If Texas Tech has a less than stellar day from deep, that creates a real opportunity for Akron to keep things very close and potentially spring the upset. 

Akron vs Texas Tech prediction: Akron +8.5 available at time of publishing. Playable to +7.5

2:50 PM ET
Fri Mar 20
CBS
Tennessee State - NCAAB
Iowa State Cyclones
Tigers
Iowa State
Point Spread Pick
Iowa State Win -24.5(-115)

#15 seed Tennessee State Tigers will get ready to take on the #2 seed Iowa State Cyclones on the second day of first-round matchups. Tennessee State comes out of the Ohio Valley Conference, where they dominated Morehead State in the championship game, shooting 49.3% from the floor. The Tigers have three players averaging double figures this season, led by Aaron Nkrumah with 17.6 points per game, and with Travis Harper II right behind him at 17.3. This backcourt is talented and capable of creating offense, but this matchup represents a major jump in competition. Earlier in the season, Tennessee State faced Tennessee and suffered a 29-point loss – something that could foreshadow what’s ahead here.  


On the other side, Iowa State has been one of the more dynamic offensive teams in the country. According to KenPom, they rank 21st in adjusted offensive efficiency, scoring 123.8 points per 100 possessions. Milan Momcilovic leads the Cyclones with 17.1 points per game and presents a matchup nightmare – he can score at the rim and stretch defenses, shooting an impressive 49.6% from beyond the arc. Defensively, Tennessee State has struggled, ranking near the bottom of their conference while allowing 73.3 points per game and opponents to shoot 44.4% from the field. Iowa State holds opponents to just 65.1 points per game on 42.6% shooting. The Cyclones also thrive on defensive pressure, forcing opponents into 15.3 turnovers per game. 

While Tennessee State does a solid job protecting the basketball, handling Iowa State’s aggressive defense will be a major challenge. In the end, the Cyclones simply have too much talent on both ends of the floor. While Tennessee State may have the slight rebounding advantage, I don’t expect that to make a big impact in this matchup. Look for Iowa State to control this game from start to finish and roll comfortably into the next round of the NCAA Tournament. 

Tennessee State vs Iowa State prediction: Iowa State -24.5 (-115) available at time of publishing. Playable at that number.

3:15 PM ET
Fri Mar 20
Tru TV
Hofstra Pride - NCAAB
Alabama Crimson Tide
Hofstra
Alabama
Game Totals Pick
Under 159.5(-115)

Friday’s Midwest regional in Tampa gives us the #4 Alabama Crimson Tide vs the #13 Hofstra Pride. Alabama made headlines this week as the team’s second leading scorer was arrested on drug charges and is likely to miss the tournament as a result. That has people sniffing around at this game for an upset. Hofstra closed the season hot, winning their final 7 games on the way to the Colonial title. I don’t know that I want to risk that upset pick, or maybe even the spread, but I do like this game total to stay under 159.5.

Anytime Alabama is involved, there is a threat the score goes to the moon. They play faster than anyone, and they take the first good shot they see. Hofstra is the opposite. They sit outside the top 300 in terms of tempo. They are, however, excellent beyond the arc, and that is the characteristic that is almost always present with the upset-seekers. So why the under? Alabama is missing a key scorer, and Hofstra likes to play slow. Hofstra can’t win a track meet. If they can protect the ball and shorten the number of possessions enough to stay in it early, it will almost certainly be a low-scoring game. And if they can’t compete? They will probably get blown out altogether. This should be an under.

Hofstra vs Alabama Prediction: Under 159.5 (-110) available at the time of publishing. Playable to 155.5.

Vote on who will win!

4:10 PM ET
Fri Mar 20
TNT
Utah State Aggies - NCAAB
Villanova Wildcats
Utah State
Villanova
Point Spread Pick
Utah State -1.5(-115)

Friday’s West regional action from San Diego includes the Utah State Aggies vs the Villanova Wildcats in an 8-vs-9 matchup. This matchup is intriguing because the teams are similar, and both have quietly put together outstanding seasons that most have not noticed. Villanova pretty well handled everyone not named UConn and St. John’s. Utah St smoothly ran through the Mountain West with just a couple of hiccups here or there. Honestly, I think Utah State is under-seeded, and I think they are just better, so I am taking the Aggies to cover -1.5.

Utah State is hyper efficient. They don’t turn the ball over, they don’t shoot a lot of threes, and they aren’t particularly flashy. What they do, however, is get into the paint and score. A lot. They have the 11th best 2-pt% in the nation, which also leads the way to the 14th best effective FG%. They are just smooth and efficient. Nova isn’t bad, but they don’t do a lot of outstanding things. They will likely need to get hot from outside to beat the Aggies, and I don’t like that they are playing on the other side of the country. A lot lines up will for the Aggies here.

Utah State vs Villanova Prediction: Utah State -1.5 (-110) available at the time of publishing. Playable at that number.

6:50 PM ET
Fri Mar 20
Iowa Hawkeyes
Clemson Tigers- NCAAB
Iowa
Clemson
Game Totals Pick
Under 129.0(-115)

The Iowa Hawkeyes and the Clemson Tigers will meet in Tampa Bay for the first round of the NCAA Tournament. The game will tip off at 6:30pm EST on Friday and should be one of the best games of the day. The eight vs nine matchup is usually a toss-up and the spread indicates that it will be a close finish. The winner of this one will likely play Florida in the round of 32 and have the opportunity to shock the world. Iowa is a short favorite as the nine seed in this one, but my best bet of the game is the under. The total is currently set at 129 points and that is the play here.

I am taking the under in this game because both teams play at a very slow pace and will look to slow the game down as much as possible. According to KenPom, Iowa is ranked #357 in adjusted tempo while Clemson is ranked #333. Neither team is ranked highly in points per game, so I do not expect points to be that many points to be scored. The total has finished under the number in 60 percentage of Clemson’s games this season and I expect that trend to continue here. Take the under.

*Under 129 available at time of publishing. Playable at 128*

Vote on who will win!

7:25 PM ET
Fri Mar 20
TBS
Point Spread Pick
UCLA -5.5(-115)

The UCF Knights and the UCLA Bruins will face off on Friday in Philadelphia for the first round of the NCAA Tournament. The game will tip off at 7:25pm EST in Xfinity Mobile Arena before UConn and Furman take the court afterwards. UCLA made it to the Big 10 semifinals last weekend and are playing like we expected in the preseason as of late. They struggled early in the season but have seemed to turn the corner recently, so I am backing them to cover this spread.

UCLA is -5.5 and that is my best bet of the game. I like UCLA to cover against UCF because I believe their offense will be too much for the UCF defense. According to KenPom, the Knights are ranked just #235 nationally in effective field goal percentage and #187 in three-point percentage. The Bruins offense is ranked #16 in three-point percentage and should have success from beyond the arc here. Guard play is important in March and UCLA has three great guards in Donovan Dent, Trent Perry and Skyy Clark. I am backing them to cover here and would not be surprised if they challenge UConn in the round of 32. Take UCLA to over in this one.

*UCLA -5.5 available at time of publishing. Playable at -6*

7:35 PM ET
Fri Mar 20
Tru TV
Queens University
Purdue Boilermakers
Royals
Purdue
Point Spread Pick
Purdue -25.5(-115)

#2 Purdue draws #15 Queens to open the West regional on Friday. You probably know about Purdue, who is perennially among the best teams in the nation. What about Queens? The Royals are fairly new to Division I, and this is actually their first year of tournament eligibility. They won the ASUN, but they are going to have all sorts of trouble with Purdue. Queens was smoked by every power conference opponent they played this season, and Purdue should do the same. This is a big number, but let’s take it at Purdue -25.5.

The biggest concern here is the Royals’ tragic defense, which ranks outside the top 300 nationally. That’s a problem. The Boilermakers are going to be able to score in just about any way they want, and they will also likely control the rebounding at a 3-1 rate. Queens likes to play fast and shoot a lot, but this is a disaster matchup for them as Purdue just doesn’t allow teams to get into that kind of offensive rhythm. There is no way Purdue takes down Michigan on Sunday and then struggles in the first round, right? Give me the Boilermakers to cover.

Queens vs Purdue Prediction: Purdue -25.5 (-110) available at the time of publishing. Playable at that number.

6:40 PM ET
Yesterday
truTV
UMBC Retrievers
Howard Bison - NCAAB
UMBC
Howard
Money Line Pick
Howard Win(+120)

The First Four can have as much drama as the Final Four, and the price in this contest reflects that. Let’s start with how both teams arrived here: via a heater. The Retrievers have won 12 straight dating back to January, when they lost against Vermont. Howard has rattled off 8 wins in its own right. The question begs: which team’s stock is higher? That would be UMBC.

Fabled for being the only team ever to orchestrate a 16-vs-1 upset in the first round, the trivia point is something that begets familiarity to the betting market in a spot like this one. The Retrievers have pedigree. Howard? It has been to the Big Dance 5 times but has never won a game. Based on these talking points alone, who do you think the market likes? UMBC, of course.

However, this is a quality opportunity for the Bison to get out of the First Four and win their first-ever tournament game. Both these teams have balance on both sides of the ball, but what is key in a game that is prognosticated to be settled by a basket is how each side handles key possessions. Edge: Howard. The Bison commit fewer turnovers and move the ball better overall — and as luck would have it, they are among the best in the country in creating turnovers and minimizing assists. In clutch time, that metric is big where every possession counts. Book the Bison.

UMBC vs Howard prediction: Howard ML (+120) available at time of publishing. Playable at that number.

Vote on who will win!

9:10 PM ET
Yesterday
truTV
Texas Longhorns
NC State Wolfpack - NCAAB
Texas
NC State
Point Spread Pick
Texas -1.0(-109)

The Texas Longhorns will take on the NC State Wolfpack in a First Four matchup on Tuesday night. It’s somewhat surprising to see Texas in the NCAA Tournament after dropping 5 of its las 6 games, but that’s neither here nor there. NC State hasn’t fared much better, also losing 5 of its last 6 — so both teams enter this matchup looking to regain momentum. Both teams have plenty of talent, but only one will be moving on to take on the #6 seed BYU in the first round.  

For Texas, the key will be establishing a physical presence inside — crashing the boards and forcing NC State into tough, physical possessions. This Texas team is bigger, stronger and has a significant rebounding advantage heading into this matchup with Dailyn Swain (7.6 rpg) and Matas Vokietaitis (6.8 rpg). NC State will lean on Ven-Allen Lubin to anchor its rebounding effort, but Texas physicality inside should limit second-chance opportunities for the Wolfpack. Offensively, both teams were nearly identical — with Texas averaging 83.8 points per game and NC State close behind at 83.7. Defensively, the Longhorns struggled this season — allowing 76.8 ppg. However, the Wolfpack haven’t been much better — giving up 76.5. This game will likely come down to which team can dominate inside, and that’s where Texas has the clear advantage. With their ability to control the boards and shut down the driving lanes, the Longhorns should be able to take control of this matchup as the game goes on. Texas is also shooting 75.2% from the free-throw line, so if it establishes a physical presence in the paint, expect UT to get to the line and create separation late in the game. 

Texas vs NC State prediction: Texas -1 (-109) available at time of publishing. Playable at that number.

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College basketball picks for the 2025/26 season. Our experts crunch the numbers, betting trends, injury reports, and much more to produce the best free college basketball picks and every day throughout the season and into March Madness itself. 

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The disparity is a big thing in many college basketball matchups and as such Moneyline betting will often see small odds about a favorite. Betting against the spread is very common, for this reason. It allows bettors to wager on the big favorites, who are expected to win,  at better odds, but also the opportunity to bet the underdog. These are the main reasons why college basketball against the spread betting is so popular, but it is also  one of our most popular college basketball picks on Pickswise. This is because knowing when an underdog might keep a game close or when potentially evenly matched teams might have blowout is very hard to predict without all the research, expertise, analysis and data our team has at its disposal. 

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At Pickswise we don’t believe in chance bets, our expert team comb through all the data, do all the analysis and provide all their research so you can have confidence in our College basketball picks.

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