USA vs Ecuador Prediction, Odds and Picks for Tomorrow, 10/10/25

The USMNT have struggled for consistency for much of the year, but they signed off their September international friendly schedule with a 2-0 victory over Japan and can follow up by defeating Ecuador at Q2 Stadium in Austin, Texas. Stars and Stripes head coach Mauricio Pochettino has chosen an experienced squad featuring 12 players with at least 20 caps. He has been mixing up his team selections but may be tempted to keep faith with the bulk of the players responsible for beating Japan, including Alejandro Zendejas and Folarin Balogun, who got on the scoresheet.

Ecuador are a well-organized opposition, who finished 2nd in South American World Cup qualifying, having lost just 2 of 18 games. But El Tri have travelled to Texas without talismanic midfielder Moises Caicedo and they may struggle to avoid defeat.

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