Arizona State Sun Devils vs Santa Clara Broncos Prediction, Odds and Picks for Saturday, 12/13/25

The Santa Clara Broncos and Arizona State Sun Devils meet at Lee’s Family Forum in Henderson, Nevada on a neutral floor. The Broncos are looking to bounce back following a 98-71 loss at New Mexico as a 1-point underdog, and Santa Clara has dropped two of the past four games, while going 1-2-1 against the spread (ATS) in the span. The Over has cashed in 3 in a row, too, if you’re interested in a Same Game Parlay (SGP). The Broncos’ defense has struggled, allowing 71 or more points in four consecutive outings — including 98 points last time out against UNM.

The Sun Devils dropped Northern Arizona last time out in a 73-48 victory, covering as a 16-point favorite. The Sun Devils, runners-up at the Maui Invitational, have won 6 of the past 7 games, while covering 5 of the past 6 outings. Arizona State is 7-2 ATS in the past 9 games, too. On a neutral floor, Sparky has won and covered in 3 of 4 games, too. Arizona State is a strong play in Henderson against a Santa Clara team not playing very good basketball lately. I’m backing the battle-tested Sun Devils to get the job done outright.

Arizona State vs Santa Clara prediction: Arizona State ML (+125) available at time of publishing. Playable to +110.

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